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The map label for this gene is appB [H]

Identifier: 159185280

GI number: 159185280

Start: 2565056

End: 2566054

Strand: Direct

Name: appB [H]

Synonym: Atu2588

Alternate gene names: 159185280

Gene position: 2565056-2566054 (Clockwise)

Preceding gene: 159185279

Following gene: 15889846

Centisome position: 90.27

GC content: 56.76

Gene sequence:

>999_bases
ATGCTGCGGTATATAATCAAGCGCATCCTCGTCATGATCCCCACGCTGATCCTGATCTCGATGCTGGTCTTCACCATCAT
CGAACTGCCGCCGGGCGATTATTTCGAAAGCTACGTCGCCGAGCTGCGCGCGATGGGCGAGACGGCAAACCTTGCCGAAA
TCGAGGAATTGCGCACCCGTTACGGTTTCGATCAGCCGGCACCGATCCGCTATTTCCGCTGGGCGACCGGCATGCTGGTC
GGCGATTTCGGTTATTCCTTCGAATATCAGCTGCCGGTCAGCGATGTGGTGGGAGACCGCCTCTGGCTGACGGTTCTGGT
CTCCTTCGTCACCATCATCGTCACCTGGATTCTTGCCTTTCCAATCGGCATCTATTCCGCCACGCATAAATACAGCTGGG
GCGATTACGGGCTCACCTTCCTCGGCCTGCTCGGCATCGCCATTCCCAACTTCATGCTGGCACTGATCCTGATGTATTTC
GCCAATATCTGGTTCGGCATCTCCATCGGCCATCTGATGGACCGGGAATATCTGAACCAGGCGATGAGCTGGGCGAAGTT
CAAATCGATCCTCGAACATATCTGGATCCCCGTCCTCATCATCGGAACGGCAGGCACTGCCGGCATGATCCGCCGCCTGC
GCGCCAATCTGCTGGACGAGTTGCAGAAACAATATGTGGTGACAGCCCGCGCCAAGGGGCTGCACCCCTTTAAGGTGCTG
ATCAAATATCCGCTGCGCATGGCGCTGAATTTCTTCATTTCGGATATCGGCTCGATCCTGCCCGCCATCATCTCAGGCGC
TGAAATCACCGCCGTCGTTCTGTCGCTCGAAACCACTGGCCCCATGCTCATCCGGGCTTTGCAAAGCCAGGATATGTATC
TTGCCGGCTCGTTCCTGATGTTCCTGGCTTTCCTGACGGTGATCGGCGTTCTGGTGTCGGATATCGCCCTTGCCATACTC
GACCCGCGCATCCGCTTCGGAGGTGGTAACGTCAAATGA

Upstream 100 bases:

>100_bases
ATGCGAAATGTGCCGGACAAGGCGCTTTTCGGTTATGAGCCCACATCCTATCTCGGCGTCTATATGCCGGATGCCTTCTG
GTATGACGGAGACGCCTGAT

Downstream 100 bases:

>100_bases
CTTCATCCATTCCGAAATCAGGCGAAGCGCTGCCCCATTACGTCTCGACGGCACCCTTCGACCCGTCGCTCATCGAACCC
AACACCTCTGGAATGGCGGC

Product: ABC transporter, membrane spanning protein (oligopeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLRYIIKRILVMIPTLILISMLVFTIIELPPGDYFESYVAELRAMGETANLAEIEELRTRYGFDQPAPIRYFRWATGMLV
GDFGYSFEYQLPVSDVVGDRLWLTVLVSFVTIIVTWILAFPIGIYSATHKYSWGDYGLTFLGLLGIAIPNFMLALILMYF
ANIWFGISIGHLMDREYLNQAMSWAKFKSILEHIWIPVLIIGTAGTAGMIRRLRANLLDELQKQYVVTARAKGLHPFKVL
IKYPLRMALNFFISDIGSILPAIISGAEITAVVLSLETTGPMLIRALQSQDMYLAGSFLMFLAFLTVIGVLVSDIALAIL
DPRIRFGGGNVK

Sequences:

>Translated_332_residues
MLRYIIKRILVMIPTLILISMLVFTIIELPPGDYFESYVAELRAMGETANLAEIEELRTRYGFDQPAPIRYFRWATGMLV
GDFGYSFEYQLPVSDVVGDRLWLTVLVSFVTIIVTWILAFPIGIYSATHKYSWGDYGLTFLGLLGIAIPNFMLALILMYF
ANIWFGISIGHLMDREYLNQAMSWAKFKSILEHIWIPVLIIGTAGTAGMIRRLRANLLDELQKQYVVTARAKGLHPFKVL
IKYPLRMALNFFISDIGSILPAIISGAEITAVVLSLETTGPMLIRALQSQDMYLAGSFLMFLAFLTVIGVLVSDIALAIL
DPRIRFGGGNVK
>Mature_332_residues
MLRYIIKRILVMIPTLILISMLVFTIIELPPGDYFESYVAELRAMGETANLAEIEELRTRYGFDQPAPIRYFRWATGMLV
GDFGYSFEYQLPVSDVVGDRLWLTVLVSFVTIIVTWILAFPIGIYSATHKYSWGDYGLTFLGLLGIAIPNFMLALILMYF
ANIWFGISIGHLMDREYLNQAMSWAKFKSILEHIWIPVLIIGTAGTAGMIRRLRANLLDELQKQYVVTARAKGLHPFKVL
IKYPLRMALNFFISDIGSILPAIISGAEITAVVLSLETTGPMLIRALQSQDMYLAGSFLMFLAFLTVIGVLVSDIALAIL
DPRIRFGGGNVK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=326, Percent_Identity=29.1411042944785, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=26.6862170087977, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789888, Length=333, Percent_Identity=28.2282282282282, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788504, Length=369, Percent_Identity=28.7262872628726, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787497, Length=329, Percent_Identity=25.8358662613982, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=27.6073619631902, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=25.9398496240602, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37324; Mature: 37324

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYIIKRILVMIPTLILISMLVFTIIELPPGDYFESYVAELRAMGETANLAEIEELRTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
YGFDQPAPIRYFRWATGMLVGDFGYSFEYQLPVSDVVGDRLWLTVLVSFVTIIVTWILAF
CCCCCCCCHHHHHHHHHCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIGIYSATHKYSWGDYGLTFLGLLGIAIPNFMLALILMYFANIWFGISIGHLMDREYLNQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMSWAKFKSILEHIWIPVLIIGTAGTAGMIRRLRANLLDELQKQYVVTARAKGLHPFKVL
HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IKYPLRMALNFFISDIGSILPAIISGAEITAVVLSLETTGPMLIRALQSQDMYLAGSFLM
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCHHHHHHHHCCCHHHHHHHHH
FLAFLTVIGVLVSDIALAILDPRIRFGGGNVK
HHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure
MLRYIIKRILVMIPTLILISMLVFTIIELPPGDYFESYVAELRAMGETANLAEIEELRTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
YGFDQPAPIRYFRWATGMLVGDFGYSFEYQLPVSDVVGDRLWLTVLVSFVTIIVTWILAF
CCCCCCCCHHHHHHHHHCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIGIYSATHKYSWGDYGLTFLGLLGIAIPNFMLALILMYFANIWFGISIGHLMDREYLNQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMSWAKFKSILEHIWIPVLIIGTAGTAGMIRRLRANLLDELQKQYVVTARAKGLHPFKVL
HHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IKYPLRMALNFFISDIGSILPAIISGAEITAVVLSLETTGPMLIRALQSQDMYLAGSFLM
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCHHHHHHHHCCCHHHHHHHHH
FLAFLTVIGVLVSDIALAILDPRIRFGGGNVK
HHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]