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The map label for this gene is murAB

Identifier: 57652146

GI number: 57652146

Start: 2175902

End: 2177161

Strand: Reverse

Name: murAB

Synonym: SACOL2116

Alternate gene names: 57652146

Gene position: 2177161-2175902 (Counterclockwise)

Preceding gene: 57652147

Following gene: 57652145

Centisome position: 77.49

GC content: 34.92

Gene sequence:

>1260_bases
ATGGCTCAAGAGGTAATAAAAATAAGAGGTGGACGCACACTAAATGGGGAAGTTAATATCAGTGGCGCGAAAAACAGTGC
TGTAGCTATCATTCCTGCAACATTATTAGCTCAAGGACATGTGAAATTAGAAGGGTTACCGCAAATCTCTGATGTTAAAA
CTTTAGTGAGTTTATTAGAAGATTTAAATATTAAGGCATCACTAAATGGTACGGAATTAGAAGTTGATACAACTGAAATA
CAAAATGCTGCATTACCAAATAATAAAGTTGAATCATTACGTGCTTCATACTATATGATGGGTGCCATGTTAGGTAGATT
TAAAAAATGTGTGATTGGTTTACCGGGAGGATGTCCACTTGGGCCACGTCCAATTGATCAACATATTAAAGGATTTAAAG
CTTTAGGTGCTGAAATTGATGAATCAAGTACGACATCAATGAAAATCGAAGCTAAAGAGTTAAAAGGTGCACATATTTTT
CTAGATATGGTTAGCGTAGGTGCAACAATTAACATTATGCTAGCTGCAGTTTATGCAACAGGACAAACTGTAATTGAAAA
TGCTGCTAAAGAACCGGAAGTAGTTGATGTTGCTAACTTCTTAACAAGTATGGGAGCTAATATTAAGGGAGCGGGTACAT
CAACAATTAAAATCAATGGCGTCAAAGAATTACATGGTTCTGAGTATCAAGTTATACCTGATAGAATTGAAGCAGGCACA
TATATGTGTATCGCTGCAGCATGTGGAGAAAATGTTATATTAAATAATATTGTTCCGAAACATGTAGAAACATTAACTGC
TAAATTTAGTGAATTAGGTGTGAATGTTGATGTAAGAGACGAAAGAATTCGCATCAATAATAATGCGCCATATCAATTTG
TTGATATTAAAACACTAGTATATCCAGGTTTTGCTACTGATTTGCAACAGCCTATTACACCATTATTATTTATGGCAAAT
GGTCCTTCATTTGTAACTGATACGATTTATCCGGAGCGTTTTAAACATGTTGAAGAATTAAAGCGCATGGGTGCAAATAT
TGAAGTTGACGAAGGCACAGCAACGATAAAACCATCAACATTACATGGTGCTGAAGTTTATGCTAGCGATTTAAGAGCAG
GAGCTTGTTTAATTATTGCTGGTTTAATTGCTGAGGGTGTAACTACAATTTACAATGTTAAACATATTTATAGAGGTTAT
ACAGATATTGTAGAACACTTAAAAGCTTTAGGTGCAGATATTTGGACGGAAACTGTATAG

Upstream 100 bases:

>100_bases
TTAACGATTAAAATAAACTATTTTACAAATAAAGTAAAATTAATTTATAATGCTAATAATGCAAAAAATTAAAAAGTAAT
GGACAAAGGAGATAAATGAT

Downstream 100 bases:

>100_bases
ATTTATCTTGTTTTGTGGTATAATAATTATACTGATTAAAAAATGGTGTTCGTTTACATTCTAAATTTATTGATGAGAGG
TGAAGATGATGGAAGTATGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEI
QNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIF
LDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGT
YMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMAN
GPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGY
TDIVEHLKALGADIWTETV

Sequences:

>Translated_419_residues
MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEI
QNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIF
LDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGT
YMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMAN
GPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGY
TDIVEHLKALGADIWTETV
>Mature_418_residues
AQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQ
NAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFL
DMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTY
MCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANG
PSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYT
DIVEHLKALGADIWTETV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=412, Percent_Identity=42.4757281553398, Blast_Score=329, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_STAAB (Q2YUM9)

Other databases:

- EMBL:   AJ938182
- RefSeq:   YP_417466.1
- ProteinModelPortal:   Q2YUM9
- SMR:   Q2YUM9
- STRING:   Q2YUM9
- EnsemblBacteria:   EBSTAT00000011573
- GeneID:   3794127
- GenomeReviews:   AJ938182_GR
- KEGG:   sab:SAB2008c
- eggNOG:   COG0766
- GeneTree:   EBGT00050000024856
- HOGENOM:   HBG482701
- OMA:   MKKIVIN
- ProtClustDB:   PRK12830
- BioCyc:   SAUR273036:SAB2008C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45076; Mature: 44944

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLE
CCCCEEEECCCEEECCEEEECCCCCCEEEEEEHHHHHCCCEEECCCCCHHHHHHHHHHHH
DLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPL
CCCEEEECCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
GPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYAT
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCEEEEEHHHHCCHHEEEEEHHHHC
GQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGT
CHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHCCCCEEECCHHHCCCC
YMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLV
EEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCEEEEEEEEEE
YPGFATDLQQPITPLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPST
ECCCHHHHHCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHCCCCEEECCCCEEECCCC
LHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADIWTETV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
AQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLE
CCCEEEECCCEEECCEEEECCCCCCEEEEEEHHHHHCCCEEECCCCCHHHHHHHHHHHH
DLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPL
CCCEEEECCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
GPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYAT
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCEEEEEHHHHCCHHEEEEEHHHHC
GQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGT
CHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHCCCCEEECCHHHCCCC
YMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLV
EEEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCEEEEEEEEEE
YPGFATDLQQPITPLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPST
ECCCHHHHHCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHCCCCEEECCCCEEECCCC
LHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADIWTETV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA