| Definition | Staphylococcus aureus subsp. aureus COL chromosome, complete genome. |
|---|---|
| Accession | NC_002951 |
| Length | 2,809,422 |
Click here to switch to the map view.
The map label for this gene is kdpD [H]
Identifier: 57650752
GI number: 57650752
Start: 2133722
End: 2136379
Strand: Direct
Name: kdpD [H]
Synonym: SACOL2070
Alternate gene names: 57650752
Gene position: 2133722-2136379 (Clockwise)
Preceding gene: 57650733
Following gene: 57650753
Centisome position: 75.95
GC content: 31.9
Gene sequence:
>2658_bases ATGTCAAACACTGAATCGCTAAACATAGGAAAAAAGCGTGGATCTTTAACAATTTACATCGGTTACAGTCCAGGTGTTGG TAAAACATTTGAGATGCTTTCAAATGCCATTGAACTATTTCAAAGTAACGTTGATATTAAAATAGGATATATTGAACCGC ATCAGCGTGATGAAACAAATGCATTAGCTGAACAATTACCTAAAATCACAACCAATTTTACTAAACATGGTAGTCATCAT TTTCAATATTTAGATGTCGACCGCATAATCGAAGAATCGCCGACAATAGTACTTATCGATGAGTTAGCACATACGAATAT TTCTAGAGATCGTCATGAGAAACGATATATGGATATTGAAGAAATTTTAAATCATGGTATCGATGTTCATACCACTTTGA ACATTCAACATATTGAAAGTTTAAGTAGTCAAATTGAACTGATGACCGGTGTACATGTTAAAGAACGTGTACCCGACTAT TTCATAATGAGCGCCGATGTATTAGAAGTCGTAGATATCTCACCTGAACAATTAATTAAACGCTTAAAAGCTGGCAAGGT ATATAAAAAGGATAGGCTAGATGTAGCATTTAGTAATTTCTTTACGTATGCCCACCTAAGCGAACTGCGTACATTGACGT TAAGAACAGTTGCCGACTTGATGAGTGATAAAGAAAAAGTCCGACACAACCATAAAACGTCACTCAAACCTCATATTGCT GTGGCAATTAGTGGGAGCATTTATAATGAAGCAGTAATTAAAGAGGCATTCCATATTGCTCAAAAAGAACATGCGAAGTT CACTGCTATTTATATAGATGTATTCGAAAAAAACAGGCAATATAAAGATAGTCAAAAGCAAGTGCATCAACATCTCATGC TTGCAAAATCATTAGGAGCAAAAGTAAAAGTAGTTTATAGCCAAACCGTTGCATTAGGATTAGACGAATGGTGTAAAAAT CAAGATGTAACCAAATTAATTATCGGACAACATATTAGAAATAAGTGGCGAGACTTTTTCAATACACCTTTAATTGACCA TTTAATGTCCTTTGAACATAGCTATAAAATCGAAATCGTTCCAATCAAACAAATACCTGTTGAATTGAAAATGAACAAAT CACCCTATCGTCCTAAAGGCAAACGTTTCGCCATAGATATGTTAAAAATGATTTTGATTCAAATAATTTGTGTAATGATG GGACTGTGGATTTATCAACTTGATAAGCATGAGTCTAGTACGATTATTTTAATGATTTTTCTCATCGGCATCATTTTATT ATCCATTTGGACGCGGTCCTTCATCATTGGCTTTTTAGCAGCAATTATTAACGTATTTGTTTTTAATTATTTTTTTACGG AACCTAGATATACATTTGAAGTATATCGCTTTGACTATCCTATTACATTTATCGTTAGCATTTTAACAAGTATTTTAACG AGTGCTTTATTAAAACAAATTAAATTCCAATACTCCATTACTAAAAAGCAACTTTATCGTACAGATTTATTATTTCAATT TAATGATTCGATTAAACAAACTTATACAGTTGAAAACTTACTAATAAATGCTGGATACCAAATTAATCAATTATTGCAAC AATCAATTACTATATACGTTATCAATCAATCGAAAGTAATTAAAACAATACCATTGCAAAACCATATCGATAATACGACT CAACAGCATGAACAAGCATTAAGCTGGGTAATTAAAAATGAAAGACAAGCTGGTGCAACAACAGATACATTTCCAGGCAT TAATAAATGGTTGATACCAATTGGCACATCTCCGATTAAAGGCATTCTAGCCATTGATTACCAAAGTTCTCAAGTGATTA ATCCATATGATGCATCAATATTAGAATCAATGTTAAATGAACTTTCTCTCGCCGTTGAAAATGTGACGTTACTTAAACAA ACGAGAGAATCCATGTTACAGGCTGAACGTCAACTGACACATTCAAATTTTTTAAGATCAATTTCGCATGACATACGTAC ACCGTTAACAACAATTATGGGAAATTTAGATATTTTAGTATCACATAGTAAAGATATGTCTGTCATAGAAAAGGAACAAT TACTTGTACATAGTTTTCAAGAAAGTCAGTATTTATATCTATTAGTGACAAATATTTTATCATTAACAAAATTACAGTCA TCAAATGTTCAGATAAAATTGCAACCTTATCTCGTTAGTGAATTAGTAGAAGAAATCGATATGATTTTAGAACGTCGCCA TTTAAAAAAGCGTATAACTGTATCATCCTCAGTAAATTTACAGTTTATACACATTGACAGTAAGTTGATTTTACAAGCTT TATTCAATTTGATTGAAAATGCAGTTAAACACACTTCTACTGACACCAAAATCAATTTATCTATTCGTTATGCTAGCTAT GAACAAATCGAATTTGCCGTTATAGACGAAGGACCTGGAATTAGTTTAGAAGAACAACAAAAGATATTCGAGCCTTTTTA CACAGGATCAAATAAATATTTTAAAGATAACCAAAAAGAAAGCATGGGACTAGGCTTATATTTAGTACAGACTATCCTAC ACAAACATCAATCAAACTTACAATATAAACCGAACCAACCACACGGCAGTATATTCTATTTCAATATATATACAGACTTT AACGAAGGAGACGTATAA
Upstream 100 bases:
>100_bases AACTTAGTTATTAAGAAATCATTAAGATGTGTATGCAGAAATAAATTTTATAGCATTTAATTGTGAAGAATATTATGATA TTGCTATCGAGGTGAAGGTT
Downstream 100 bases:
>100_bases TGCAATCTAAAATATTGATAATTGAAGATGATCACGCAATCACACATTTACTTGATGTTGCATTAACTTTAGATTATTAC AATGTAACTACAGCCGACAA
Product: sensor histidine kinase KdpD
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 885; Mature: 884
Protein sequence:
>885_residues MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHH FQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKN QDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMM GLWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTT QQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQ TRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASY EQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDF NEGDV
Sequences:
>Translated_885_residues MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHH FQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKN QDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMM GLWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTT QQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQ TRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASY EQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDF NEGDV >Mature_884_residues SNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLPKITTNFTKHGSHHF QYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDYF IMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIAV AISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKNQ DVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMG LWIYQLDKHESSTIILMIFLIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILTS ALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTTQ QHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQT RESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQSS NVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASYE QIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDFN EGDV
Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]
COG id: COG2205
COG function: function code T; Osmosensitive K+ channel histidine kinase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
Organism=Escherichia coli, GI1786912, Length=882, Percent_Identity=26.1904761904762, Blast_Score=357, Evalue=2e-99, Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=29.4605809128631, Blast_Score=96, Evalue=1e-20, Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=28.5087719298246, Blast_Score=86, Evalue=1e-17, Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=1e-16, Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=24.7787610619469, Blast_Score=82, Evalue=2e-16, Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=4e-16, Organism=Escherichia coli, GI1788279, Length=261, Percent_Identity=27.2030651340996, Blast_Score=80, Evalue=8e-16, Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=25, Blast_Score=73, Evalue=1e-13, Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=23.0452674897119, Blast_Score=66, Evalue=8e-12, Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=22.4066390041494, Blast_Score=65, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR014729 - InterPro: IPR004358 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR003852 - InterPro: IPR006016 [H]
Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 102207; Mature: 102075
Theoretical pI: Translated: 7.79; Mature: 7.79
Prosite motif: PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETN CCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH ALAEQLPKITTNFTKHGSHHFQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIE HHHHHCCHHHHHHHHCCCCCEEEECHHHHHCCCCCEEEEECHHCCCCCHHHHHHHCCCHH EILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDYFIMSADVLEVVDISPEQLIK HHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCHHHHHCCCHHHHHH RLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGA EEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHCCC KVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIV EEEEEEHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEE PIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMGLWIYQLDKHESSTIILMIF EECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH LIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHH SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYV HHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHEECCCHHHHHHHCCCEEEE INQSKVIKTIPLQNHIDNTTQQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIK EECCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCC GILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQTRESMLQAERQLTHSNFLRS CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS HHHHHHCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIEN CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECHHHHHHHHHHHHHH AVKHTSTDTKINLSIRYASYEQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKE HHHCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH SMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDFNEGDV HCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCC >Mature Secondary Structure SNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETN CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH ALAEQLPKITTNFTKHGSHHFQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIE HHHHHCCHHHHHHHHCCCCCEEEECHHHHHCCCCCEEEEECHHCCCCCHHHHHHHCCCHH EILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDYFIMSADVLEVVDISPEQLIK HHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCHHHHHCCCHHHHHH RLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIA HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE VAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEKNRQYKDSQKQVHQHLMLAKSLGA EEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHCCC KVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKWRDFFNTPLIDHLMSFEHSYKIEIV EEEEEEHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEE PIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMGLWIYQLDKHESSTIILMIF EECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH LIGIILLSIWTRSFIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHH SALLKQIKFQYSITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYV HHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHEECCCHHHHHHHCCCEEEE INQSKVIKTIPLQNHIDNTTQQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIK EECCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCC GILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQTRESMLQAERQLTHSNFLRS CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH ISHDIRTPLTTIMGNLDILVSHSKDMSVIEKEQLLVHSFQESQYLYLLVTNILSLTKLQS HHHHHHCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC SNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVNLQFIHIDSKLILQALFNLIEN CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECHHHHHHHHHHHHHH AVKHTSTDTKINLSIRYASYEQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKE HHHCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH SMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIYTDFNEGDV HCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9226259; 11466286 [H]