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The map label for this gene is kdpE [H]

Identifier: 57650753

GI number: 57650753

Start: 2136379

End: 2137074

Strand: Direct

Name: kdpE [H]

Synonym: SACOL2071

Alternate gene names: 57650753

Gene position: 2136379-2137074 (Clockwise)

Preceding gene: 57650752

Following gene: 57650757

Centisome position: 76.04

GC content: 32.61

Gene sequence:

>696_bases
ATGCAATCTAAAATATTGATAATTGAAGATGATCACGCAATCACACATTTACTTGATGTTGCATTAACTTTAGATTATTA
CAATGTAACTACAGCCGACAATGCCACACAAGCACACTTTAAAATTCAAATTGATAAACCAGATGTCATTTTATTAGATT
TAGGTTTACCAGATAAAGATGGATTATGTTTGATTTCAGAAATCAGGCAACATACTGACATTCCTATCATTGTAATAAGT
GCAAGACAAGAAGAACAAACAATTATTCAAGCTTTAGATAACGGTGCGAATGACTATATGACTAAACCTTTTAATGTTGA
TGAGCTTCGGGCACGAATACGAGTCATCGAGAGAATCGCTAAGTCACATCAAGAAACTAACATTGTATTTACTAACGGTT
TGCTAAGCATCGACTTTGGCTCCAAATCTGTTGTTATTAATAATCAGGAGGTACATTTGACGCCAAATGAATTTAGCTTG
TTAGAACTATTGTCAAATCATAAAGGAAAAGTACTCACTTATGAGATGATATTAAAACGAATATATGGCTATGTTAATAA
GACTGAAATGCCTAGTTTAAGAGTGCATATGACATCATTAAGACAAAAACTTTCACAATGTCATGAGGACGCAAAAGATA
TTATTAAAACACATCCACGCATTGGTTATCAAATGTTGCAGTGGAAAGAGAAATAA

Upstream 100 bases:

>100_bases
TACACAAACATCAATCAAACTTACAATATAAACCGAACCAACCACACGGCAGTATATTCTATTTCAATATATATACAGAC
TTTAACGAAGGAGACGTATA

Downstream 100 bases:

>100_bases
TTAAATAAAAAAGATCGCTGCCATTAAACGAATGATTGGCAGTGATCTTTTTTATATTCAACTTATTATTTATCGCGCAC
TAGCGTCAGCAAAAAGCCCT

Product: DNA-binding response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKDGLCLISEIRQHTDIPIIVIS
ARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIAKSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSL
LELLSNHKGKVLTYEMILKRIYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK

Sequences:

>Translated_231_residues
MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKDGLCLISEIRQHTDIPIIVIS
ARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIAKSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSL
LELLSNHKGKVLTYEMILKRIYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
>Mature_231_residues
MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKDGLCLISEIRQHTDIPIIVIS
ARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIAKSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSL
LELLSNHKGKVLTYEMILKRIYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=39.2857142857143, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=32.4561403508772, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=33.7837837837838, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=29.8642533936652, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=29.3859649122807, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=28.6995515695067, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=31.5555555555556, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=31.7391304347826, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=29.0748898678414, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=27.4774774774775, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=29.4642857142857, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787229, Length=214, Percent_Identity=28.0373831775701, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI145693140, Length=210, Percent_Identity=30, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=36.1111111111111, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=26.2008733624454, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.9672131147541, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26512; Mature: 26512

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
CCCCEEEEECCCHHHHHHHHHHEEEEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCCC
GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
CEEHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
HCCCCCEEEEECCEEEEECCCCEEEEECCEEEECCCHHHHHHHHHCCCCCEEEHHHHHHH
IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC
>Mature Secondary Structure
MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKD
CCCCEEEEECCCHHHHHHHHHHEEEEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCCC
GLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIA
CEEHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKR
HCCCCCEEEEECCEEEEECCCCEEEEECCEEEECCCHHHHHHHHHCCCCCEEEHHHHHHH
IYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]