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The map label for this gene is malA [H]

Identifier: 57650463

GI number: 57650463

Start: 1586830

End: 1588479

Strand: Reverse

Name: malA [H]

Synonym: SACOL1551

Alternate gene names: 57650463

Gene position: 1588479-1586830 (Counterclockwise)

Preceding gene: 57650464

Following gene: 57650460

Centisome position: 56.54

GC content: 34.79

Gene sequence:

>1650_bases
ATGAATAAGCAATGGTGGAAAGAAGCAGTAGCATATCAAGTATATCCAAGAAGTTTTAATGATAGTAATCACGATGGTAT
TGGGGATTTACCTGGAATGATTGATAAATTGGACTACTTAAAAGATTTCGGTATCGATGTCATTTGGCTCAGTCCAATGT
TTAAATCACCTAATGATGACAATGGTTATGATATTAGTGACTACCAAGAGATTATGGATGAATTTGGAACGATGGAAGAC
TTTGATCGTTTATTAAAAGGTGTTCATGATAGAGGCATGAAGCTTATTTTAGATTTAGTTGTAAATCATACATCTGATGA
ACATCCTTGGTTTATAGAATCCAAATCTAGTAAAGACAATCCCAAACGTGATTGGTACATTTGGCAAGATCCAAAGCCAG
ATGGCTCTGAACCTAACAACTGGGAAAGTATATTTAATGGATCTACATGGGAATATGATGCTAATACTGAGCAATATTAT
TTCCATTTATTCAGTAAAAAACAACCTGATTTGAATTGGGGTAATCCGGAAGTTAGAGATGCTGTATTTGAAATGATGAA
CTGGTGGTTTGATAAAGGCATTGATGGATTTAGAGTAGATGCAATTACGCATATTAAGAAGACGTTTGAAGCGGGTGACT
TACCTGTACCTGAGGGTAAAACATATGCCCCAGCATTTGATGTAGATATGAATCAGCCAGGTATACAAACTTGGTTACAA
GAGATGAAAGATCGCTCATTAAGTAAGTATGACATTATGACTGTTGGTGAAGCGAATGGTGTAAGCCCTGATGATGCTGA
TGACTGGGTCGGGGAAGAAAATGGTAAATTTAATATGATATTCCAATTTGAACATTTGGGACTGTGGAATAGTGGTGATT
CTCACTTTGATGTAAATTCGTATAAATCTGTATTAAATAGATGGCAAAAACAACTTGAAAATAAAGGTTGGAATGCGTTG
TTTATTGAAAATCACGACCAACCACGACGTGTATCGACGTGGGGTGACGATGACAAGTATTGGTATGAATCAGCAACAAG
TCATGCAGCTGTTTATTTCTTGCAACAAGGTACGCCATTCATTTATCAAGGTCAAGAAATTGGTATGACGAATTATCCAT
TTGAAAGTATTGAAACGTTTAACGATGTTGCTGTTAAAAATGACTATCAAATAGTGAAAGCTCAAGGTGGAGATGTAGAC
GCTTTACTTGCGAAATATAAAGATGAGAACCGAGATAATTCTCGCACACCAATGCAATGGGATGATACGTTAAATGGAGG
ATTTACAAATGGTGAACCGTGGTTCCCAGTGAATCCGAATTATAAAACTATCAATGTTGCACAACAATTAGAAGATGAGC
ATTCAGTATTACAATTTTATAAAGATTTAATTCAATTAAGAAAGTCTAATGATGTATACGTATATGGTCAATTTGATTTA
GTAGATGCTGAAAATTCACAAGTTTTTGCGTACACGAGAACATTAAATGAAAAGCAAGTTCTTATTGTAGGTAATCTTAC
TAACCACGAAGCAGAATTAACTGTACCATTTGATTTAAGCCATGGAGAAGTAAAGCTATTTAATTATGATGCCAAAGTTA
ATTTAAAACAGTTACGTCCATATGAAGCATGTGTTATCGAACTAAATTAA

Upstream 100 bases:

>100_bases
TATATTGAAAAACAAAGCACAGGATGTTATTGAACTCGTCATTATAGATACAGAATTAAAAATAAGAAAATCAACACAGC
GATAGCAAAGGAGTTTTAAA

Downstream 100 bases:

>100_bases
CATATTAATATGCCCCCTAATAGAATCTAAGGCCATTTGTAGACCTATAGATATATTAGGGGGCTTCTTTGTTTTTTATT
ATTTAATCTTCGTCATAAGG

Product: alpha-D-1,4-glucosidase

Products: NA

Alternate protein names: Oligosaccharide alpha-1,6-glucosidase 3; Sucrase-isomaltase 3; Isomaltase 3 [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDFGIDVIWLSPMFKSPNDDNGYDISDYQEIMDEFGTMED
FDRLLKGVHDRGMKLILDLVVNHTSDEHPWFIESKSSKDNPKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYY
FHLFSKKQPDLNWGNPEVRDAVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPEGKTYAPAFDVDMNQPGIQTWLQ
EMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGKFNMIFQFEHLGLWNSGDSHFDVNSYKSVLNRWQKQLENKGWNAL
FIENHDQPRRVSTWGDDDKYWYESATSHAAVYFLQQGTPFIYQGQEIGMTNYPFESIETFNDVAVKNDYQIVKAQGGDVD
ALLAKYKDENRDNSRTPMQWDDTLNGGFTNGEPWFPVNPNYKTINVAQQLEDEHSVLQFYKDLIQLRKSNDVYVYGQFDL
VDAENSQVFAYTRTLNEKQVLIVGNLTNHEAELTVPFDLSHGEVKLFNYDAKVNLKQLRPYEACVIELN

Sequences:

>Translated_549_residues
MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDFGIDVIWLSPMFKSPNDDNGYDISDYQEIMDEFGTMED
FDRLLKGVHDRGMKLILDLVVNHTSDEHPWFIESKSSKDNPKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYY
FHLFSKKQPDLNWGNPEVRDAVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPEGKTYAPAFDVDMNQPGIQTWLQ
EMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGKFNMIFQFEHLGLWNSGDSHFDVNSYKSVLNRWQKQLENKGWNAL
FIENHDQPRRVSTWGDDDKYWYESATSHAAVYFLQQGTPFIYQGQEIGMTNYPFESIETFNDVAVKNDYQIVKAQGGDVD
ALLAKYKDENRDNSRTPMQWDDTLNGGFTNGEPWFPVNPNYKTINVAQQLEDEHSVLQFYKDLIQLRKSNDVYVYGQFDL
VDAENSQVFAYTRTLNEKQVLIVGNLTNHEAELTVPFDLSHGEVKLFNYDAKVNLKQLRPYEACVIELN
>Mature_549_residues
MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDFGIDVIWLSPMFKSPNDDNGYDISDYQEIMDEFGTMED
FDRLLKGVHDRGMKLILDLVVNHTSDEHPWFIESKSSKDNPKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYY
FHLFSKKQPDLNWGNPEVRDAVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPEGKTYAPAFDVDMNQPGIQTWLQ
EMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGKFNMIFQFEHLGLWNSGDSHFDVNSYKSVLNRWQKQLENKGWNAL
FIENHDQPRRVSTWGDDDKYWYESATSHAAVYFLQQGTPFIYQGQEIGMTNYPFESIETFNDVAVKNDYQIVKAQGGDVD
ALLAKYKDENRDNSRTPMQWDDTLNGGFTNGEPWFPVNPNYKTINVAQQLEDEHSVLQFYKDLIQLRKSNDVYVYGQFDL
VDAENSQVFAYTRTLNEKQVLIVGNLTNHEAELTVPFDLSHGEVKLFNYDAKVNLKQLRPYEACVIELN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=532, Percent_Identity=32.3308270676692, Blast_Score=255, Evalue=8e-68,
Organism=Escherichia coli, GI1790687, Length=554, Percent_Identity=38.4476534296029, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1786604, Length=132, Percent_Identity=34.8484848484849, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565753, Length=203, Percent_Identity=33.4975369458128, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=207, Percent_Identity=28.9855072463768, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324416, Length=575, Percent_Identity=36.5217391304348, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321726, Length=575, Percent_Identity=36.1739130434783, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6322241, Length=575, Percent_Identity=36.3478260869565, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6322021, Length=575, Percent_Identity=36.3478260869565, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6322245, Length=570, Percent_Identity=36.3157894736842, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319776, Length=574, Percent_Identity=38.3275261324042, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321731, Length=574, Percent_Identity=38.1533101045296, Blast_Score=362, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24583745, Length=579, Percent_Identity=35.0604490500864, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24583747, Length=526, Percent_Identity=35.361216730038, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24583749, Length=526, Percent_Identity=35.361216730038, Blast_Score=285, Evalue=7e-77,
Organism=Drosophila melanogaster, GI221330053, Length=585, Percent_Identity=30.5982905982906, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24586599, Length=531, Percent_Identity=32.391713747646, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24586593, Length=522, Percent_Identity=33.7164750957854, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24586597, Length=491, Percent_Identity=32.5865580448065, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586591, Length=491, Percent_Identity=34.2158859470468, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586589, Length=514, Percent_Identity=33.6575875486381, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24586587, Length=578, Percent_Identity=30.9688581314879, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI45549022, Length=546, Percent_Identity=32.2344322344322, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI281360393, Length=466, Percent_Identity=30.9012875536481, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 63906; Mature: 63906

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDFGIDVIWLSPMFKSPNDD
CCHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
NGYDISDYQEIMDEFGTMEDFDRLLKGVHDRGMKLILDLVVNHTSDEHPWFIESKSSKDN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
PKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYYFHLFSKKQPDLNWGNPEVRD
CCCCEEEECCCCCCCCCCCCHHHHCCCCCEEECCCCCEEEEEEECCCCCCCCCCCHHHHH
AVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPEGKTYAPAFDVDMNQPGIQTWLQ
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCEECCEECCCCCCCHHHHHHH
EMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGKFNMIFQFEHLGLWNSGDSHFDVNS
HHHHCCCCCEEEEEECCCCCCCCCCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCEEHHH
YKSVLNRWQKQLENKGWNALFIENHDQPRRVSTWGDDDKYWYESATSHAAVYFLQQGTPF
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCHHHHCCCCCEEEEEEECCCCE
IYQGQEIGMTNYPFESIETFNDVAVKNDYQIVKAQGGDVDALLAKYKDENRDNSRTPMQW
EEECCCCCCCCCCHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCC
DDTLNGGFTNGEPWFPVNPNYKTINVAQQLEDEHSVLQFYKDLIQLRKSNDVYVYGQFDL
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
VDAENSQVFAYTRTLNEKQVLIVGNLTNHEAELTVPFDLSHGEVKLFNYDAKVNLKQLRP
EECCCCEEEEEEECCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECHHHCCC
YEACVIELN
EEEEEEEEC
>Mature Secondary Structure
MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDFGIDVIWLSPMFKSPNDD
CCHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
NGYDISDYQEIMDEFGTMEDFDRLLKGVHDRGMKLILDLVVNHTSDEHPWFIESKSSKDN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
PKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYYFHLFSKKQPDLNWGNPEVRD
CCCCEEEECCCCCCCCCCCCHHHHCCCCCEEECCCCCEEEEEEECCCCCCCCCCCHHHHH
AVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPEGKTYAPAFDVDMNQPGIQTWLQ
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCEECCEECCCCCCCHHHHHHH
EMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGKFNMIFQFEHLGLWNSGDSHFDVNS
HHHHCCCCCEEEEEECCCCCCCCCCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCEEHHH
YKSVLNRWQKQLENKGWNALFIENHDQPRRVSTWGDDDKYWYESATSHAAVYFLQQGTPF
HHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCHHHHCCCCCEEEEEEECCCCE
IYQGQEIGMTNYPFESIETFNDVAVKNDYQIVKAQGGDVDALLAKYKDENRDNSRTPMQW
EEECCCCCCCCCCHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCC
DDTLNGGFTNGEPWFPVNPNYKTINVAQQLEDEHSVLQFYKDLIQLRKSNDVYVYGQFDL
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
VDAENSQVFAYTRTLNEKQVLIVGNLTNHEAELTVPFDLSHGEVKLFNYDAKVNLKQLRP
EECCCCEEEEEEECCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEECCCEECHHHCCC
YEACVIELN
EEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]