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The map label for this gene is malR [H]

Identifier: 57650464

GI number: 57650464

Start: 1588495

End: 1589514

Strand: Reverse

Name: malR [H]

Synonym: SACOL1552

Alternate gene names: 57650464

Gene position: 1589514-1588495 (Counterclockwise)

Preceding gene: 57650465

Following gene: 57650463

Centisome position: 56.58

GC content: 31.37

Gene sequence:

>1020_bases
ATGGTTACGATTAAAGATGTTGCACTAAAAGCCGGTGTTTCTCCTTCGACAGTTTCAAGAGTTATAAAAGGAAATCAACG
TATTAGCGAAGCGACAATTTCAAAAGTGAAGAAAGTTATGGAAGAATTGAATTATTTTCCTAATACCGCTGCTAGAACTT
TAATTACAAACCAAACATATAAAATTGGTTTAGTGTTAAAAGGGTCTGAGGAGCCTATTCGACTGAATCCATTCTACATC
AATGTATTGCTAGGAATTTCTGAAACGTGTAACCAGCATGGCTATGGTACACAAACGACAGTCTCAAATAATATGAATGA
TTTAATGGATGAAGTTTATAAAATGATTAAACAACGAATGGTTGATGCGTTTATACTGCTCTATTCAAAAGAAAATGATC
CGATTAAACAAATGTTAATTGATGAAAGCATGCCATTTATTGTGATTGGTAAGCCTACATCGGATATAGATCATCAATTT
ACACATATAGATAATGATAATATATTAGCTTCTGAAAATTTGACACGACATGTTATTGAACAAGGTGTAGATGAATTAAT
ATTTATTACAGAAAAAGGAAATTTTGAAGTTTCAAAAGATAGAATTCAAGGATTTGAAACGATAGCTTCTCAAAATAAAA
TTAATTATCAAATTATTGAGACTAGTAATGAAAGAGAAGTTATTTTTAATTACATGCAAAATCTACATACGCGTTTGAAG
GACCCAAATATTAAACAGGCAATCATTTCGTTAGATGCTATGTTACATTTAGCGATTTTAAGTGTCCTATATGAACTTAA
TATTGAAATTCCGAAAGATGTAATGACAGCAACGTTCAATGATTCTTATTTAACCGAAATTGCGTCACCACCACAAACCT
GTATTGACATCAAGCCTCGAATGTTAGGTCAACAGGCTGGTGCAGCAATTTTAAATATATTGAAAAACAAAGCACAGGAT
GTTATTGAACTCGTCATTATAGATACAGAATTAAAAATAAGAAAATCAACACAGCGATAG

Upstream 100 bases:

>100_bases
TTGCACAAATCTTTTGACTTTTTTAGAAAGTGTGACTAAACTGGTATTATACAGTGGTTGGAAGCGTTTTCCAATGCAGA
AATTAACAGGAGGTGATTAA

Downstream 100 bases:

>100_bases
CAAAGGAGTTTTAAAATGAATAAGCAATGGTGGAAAGAAGCAGTAGCATATCAAGTATATCCAAGAAGTTTTAATGATAG
TAATCACGATGGTATTGGGG

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPRMLGQQAGAAILNILKNKAQD
VIELVIIDTELKIRKSTQR

Sequences:

>Translated_339_residues
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPRMLGQQAGAAILNILKNKAQD
VIELVIIDTELKIRKSTQR
>Mature_339_residues
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYI
NVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPRMLGQQAGAAILNILKNKAQD
VIELVIIDTELKIRKSTQR

Specific function: Transcriptional repressor of the malA gene for maltase [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=311, Percent_Identity=27.3311897106109, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=28.3489096573209, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787948, Length=327, Percent_Identity=26.2996941896024, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790369, Length=348, Percent_Identity=25.5747126436782, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787906, Length=207, Percent_Identity=27.0531400966184, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786268, Length=293, Percent_Identity=26.2798634812287, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789202, Length=312, Percent_Identity=24.6794871794872, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790715, Length=326, Percent_Identity=23.6196319018405, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=22.1854304635762, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786540, Length=324, Percent_Identity=23.7654320987654, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789456, Length=352, Percent_Identity=24.7159090909091, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994940, Length=294, Percent_Identity=22.108843537415, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38391; Mature: 38391

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTY
CEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEE
KIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRM
EEEEEEECCCCCEEECCEEEEEEECCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQFTHIDNDNILASENLTRHVIE
HHHHEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCEEECCHHHHHHHH
QGVDELIFITEKGNFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
CCCCCEEEEEECCCCEECHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCHHHHHHCCCCCHHHCCCHH
MLGQQAGAAILNILKNKAQDVIELVIIDTELKIRKSTQR
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCC
>Mature Secondary Structure
MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELNYFPNTAARTLITNQTY
CEEEHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECCEE
KIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVSNNMNDLMDEVYKMIKQRM
EEEEEEECCCCCEEECCEEEEEEECCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
VDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQFTHIDNDNILASENLTRHVIE
HHHHEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCHHEEECCCCEEECCHHHHHHHH
QGVDELIFITEKGNFEVSKDRIQGFETIASQNKINYQIIETSNEREVIFNYMQNLHTRLK
CCCCCEEEEEECCCCEECHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
DPNIKQAIISLDAMLHLAILSVLYELNIEIPKDVMTATFNDSYLTEIASPPQTCIDIKPR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCHHHHHHCCCCCHHHCCCHH
MLGQQAGAAILNILKNKAQDVIELVIIDTELKIRKSTQR
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7730272 [H]