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The map label for this gene is rnz [H]

Identifier: 57650460

GI number: 57650460

Start: 1582934

End: 1583854

Strand: Reverse

Name: rnz [H]

Synonym: SACOL1548

Alternate gene names: 57650460

Gene position: 1583854-1582934 (Counterclockwise)

Preceding gene: 57650463

Following gene: 57650458

Centisome position: 56.38

GC content: 33.33

Gene sequence:

>921_bases
ATGGAAGTTACATTTTTTGGAACGAGTGCAGGTTTGCCTACAAAAGAGAGAAATACACAAGCAATCGCCTTAAATTTAGA
ACCATATTCCAATTCCATATGGCTTTTCGACGTTGGTGAAGGTACACAGCACCAAATTTTACATCATGCAATTAAATTAG
GAAAAGTGACACATATATTTATTACTCATATGCATGGCGATCATATTTTTGGTTTGCCAGGATTACTTTCTAGTCGTTCT
TTTCAGGGCGGTGAACAGAAGCCGCTTACATTGGTTGGACCAAAAGGAATTAAAGCATATGTGGAAATGTCTATGAATTT
ATCAGAGTCACATTTAAACTATCCAATTACATATATTGAAATCGATGATCATCTGACATATCATCATGATGGTTTTACTG
TAGAGGCGCATTTACTTAATCATGGTATTCCATCATATGGATATAGAGTAATGGCACCTGAAACTACAGGTACAATCAAT
GTTGAAGCGTTAAAAAACATTGGTCTTGAACCAGGTCCTAAATATCAAGAAGTAAAATCTCATGATACATTTGAACATAA
TGGTCAAGTTTATCAATCAAAAGATTTTAGAGGTGAGTCCAAACAGGGTCCAGTTGTAGCAATTTTTGGTGATACAAAAC
CATGTTCTAATGAACGTGTGATTTCTAGAGATGCTGATGTGATGGTACATGAAGCGACCTATATAGATGGTGAAAAGCAT
TTAGCCAACAATTATCATCATAGCCATATTGAAGACGTATTTGCATTGATAAAAGAAGCCAATGTTAAACGTACGTTGAT
TACACATTTGAGCAATCGCTATAATACAGAAGATATAAATGAAATTTATCAAACATTGATACAAAATGAAGATACACCTA
ATTTTAATTTTGTAAAAGATTTTGATAGTTTTAAAATCTAA

Upstream 100 bases:

>100_bases
GCAAAGACGAATTTTTAACAGATTTTGATTCAAGTATAAATTAAAACTAAATTGATACAAATTTTATGATAAAATGAATT
GAAGAAAAGGAGGGGCATAT

Downstream 100 bases:

>100_bases
TGACAAAGTAATAAACAATGCTTGCCAAATAACAATAAATTATAAAAATAACCCGTCAAACACAGTGCTTGCGATGATGC
ATACATGTGTTGGCGGGTTT

Product: AtsA/ElaC family protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRS
FQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI

Sequences:

>Translated_306_residues
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRS
FQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI
>Mature_306_residues
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRS
FQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=355, Percent_Identity=29.8591549295775, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI260166619, Length=283, Percent_Identity=25.7950530035336, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI260166622, Length=283, Percent_Identity=25.7950530035336, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI145553959, Length=283, Percent_Identity=25.7950530035336, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI87082078, Length=308, Percent_Identity=41.2337662337662, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 34585; Mature: 34585

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIF
CEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEE
ITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIE
EEEECCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHCCCCEEEEE
IDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKS
ECCCEEEECCCEEEEEEEHHCCCCCCCEEEECCCCCCEEEHHHHHHCCCCCCCCHHHHCC
HDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
CCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCEEEEEEEEECCHHH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKD
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
FDSFKI
CCCCCC
>Mature Secondary Structure
MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIF
CEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEE
ITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIE
EEEECCCEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHCCCCEEEEE
IDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKS
ECCCEEEECCCEEEEEEEHHCCCCCCCEEEECCCCCCEEEHHHHHHCCCCCCCCHHHHCC
HDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKH
CCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCEEEEEEEEECCHHH
LANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKD
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
FDSFKI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA