The gene/protein map for NC_002944 is currently unavailable.
Definition Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession NC_002944
Length 4,829,781

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The map label for this gene is fabG [H]

Identifier: 41409977

GI number: 41409977

Start: 4341338

End: 4342105

Strand: Reverse

Name: fabG [H]

Synonym: MAP3879c

Alternate gene names: 41409977

Gene position: 4342105-4341338 (Counterclockwise)

Preceding gene: 41409981

Following gene: 41409976

Centisome position: 89.9

GC content: 70.44

Gene sequence:

>768_bases
GTGAACCTAGATTCGTCTGCAATGAATACTCATTCACACCGCCGCCTCGCGGTGGTGACCGGCGCGGGTTCGGGCATCGG
CCGGGCGATCGCGCTCGGGCTGGCCGCCGGGGGTGACCGCGTCGTCGCCGCCGACCTGGACGAGGCGTCGGCCGCGGCCA
CCGCCGCCGAGCAACCCGACCTGATCACCGCGGCGCCGGTGGACGTCGCCGACCCGGCACGGGTCGCCGCGCTGCGGGAC
CGCATCCACGCCGACATCGGGGTGCCCGGCGTCGTCGTCAACGCCGCCGGCTGGGACCGAACCGACCAATTCCTCAACGC
CACACCGGAATTCGCACAGAAGGTGGTGGCCATCAACTACCTGGGGCCGGTGCATGTGTGTTCGGCGTTCCTGCCCGGGA
TGATCGAGACGCACGGCGGCGGACGCGTGGTGAACGTCGCCAGCGACGCCGGCCGGGTCGGCAGCGCCGGTGAGAGCATC
TACGCCGGCGCCAAGGGCGGGGTGATCGCGCTGACCAAGTCGCTGGCCCGCGAGATGGCGCGCCACCAGATCACGGTGAA
CTGCGTGTGCCCGGGCCCGACCGACACCCCGCTGTTTCACGCCCAGCCCGAGAAGCTGAAAGAAGCACTGGTCAAAGCGA
TTCCGCTGCGCCGGCTGGCCCGGCCCGAGGAGGTCGCCGCGGCGGTGCTGTTCTTCGCCTCGCAGGCAGCCTCGTTCGTC
ACCGGACAGGTGATCAGTGTCAGCGGCGGCTTAACGATGGCAGGCTGA

Upstream 100 bases:

>100_bases
ACGCCGAGGACATCGACCGCGAACCAGGCCAGCCGCCGGAGCCTAAGCATGCAGCGAGACTACCCGCTCGGCCGCGCCGA
TCCTTGACCCGGCAACCGAG

Downstream 100 bases:

>100_bases
CTGCTATGAGCACCGAGACGAGCACCAAGACCCCACCGTCCTTCGACCGCTACGACCCGCTGGGCCTGGACGCCTTGCTG
TCCGACGACGAACGCGCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNLDSSAMNTHSHRRLAVVTGAGSGIGRAIALGLAAGGDRVVAADLDEASAAATAAEQPDLITAAPVDVADPARVAALRD
RIHADIGVPGVVVNAAGWDRTDQFLNATPEFAQKVVAINYLGPVHVCSAFLPGMIETHGGGRVVNVASDAGRVGSAGESI
YAGAKGGVIALTKSLAREMARHQITVNCVCPGPTDTPLFHAQPEKLKEALVKAIPLRRLARPEEVAAAVLFFASQAASFV
TGQVISVSGGLTMAG

Sequences:

>Translated_255_residues
MNLDSSAMNTHSHRRLAVVTGAGSGIGRAIALGLAAGGDRVVAADLDEASAAATAAEQPDLITAAPVDVADPARVAALRD
RIHADIGVPGVVVNAAGWDRTDQFLNATPEFAQKVVAINYLGPVHVCSAFLPGMIETHGGGRVVNVASDAGRVGSAGESI
YAGAKGGVIALTKSLAREMARHQITVNCVCPGPTDTPLFHAQPEKLKEALVKAIPLRRLARPEEVAAAVLFFASQAASFV
TGQVISVSGGLTMAG
>Mature_255_residues
MNLDSSAMNTHSHRRLAVVTGAGSGIGRAIALGLAAGGDRVVAADLDEASAAATAAEQPDLITAAPVDVADPARVAALRD
RIHADIGVPGVVVNAAGWDRTDQFLNATPEFAQKVVAINYLGPVHVCSAFLPGMIETHGGGRVVNVASDAGRVGSAGESI
YAGAKGGVIALTKSLAREMARHQITVNCVCPGPTDTPLFHAQPEKLKEALVKAIPLRRLARPEEVAAAVLFFASQAASFV
TGQVISVSGGLTMAG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=35.7692307692308, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=35.6846473029046, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=34.2857142857143, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=32.5, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=31.6602316602317, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=27.9475982532751, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=30.8, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI59889578, Length=221, Percent_Identity=32.579185520362, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI142976729, Length=189, Percent_Identity=30.6878306878307, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=30.8943089430894, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=28.4974093264249, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=29.6747967479675, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4503817, Length=222, Percent_Identity=28.3783783783784, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI83715985, Length=250, Percent_Identity=29.6, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI25282469, Length=216, Percent_Identity=27.3148148148148, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40807363, Length=256, Percent_Identity=25.390625, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=30.6122448979592, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=25.3112033195021, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=28.1553398058252, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150247226, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19743808, Length=217, Percent_Identity=27.6497695852535, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40548397, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=200, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=209, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI50726952, Length=212, Percent_Identity=32.0754716981132, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=33.8912133891213, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=36, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=31.8181818181818, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=34.6774193548387, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=36.8421052631579, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=30.2904564315353, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.5785123966942, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.7937743190661, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=30.327868852459, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=24.4274809160305, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=42.3868312757202, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=38.0165289256198, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=31.6, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=33.1983805668016, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=33.0645161290323, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=29.8755186721992, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=28.7128712871287, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=29.9465240641711, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=30, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=30, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=32.8, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=26.1538461538462, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=27.9187817258883, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=28.7937743190661, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=206, Percent_Identity=32.0388349514563, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=27.4809160305344, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=24.6153846153846, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=28.2258064516129, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=25.4901960784314, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.2388059701493, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=28.735632183908, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=27.5303643724696, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=28.4, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=190, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=219, Percent_Identity=26.9406392694064, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=37.9591836734694, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=33.2, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=32.4, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=34.4262295081967, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=30.4932735426009, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=29.5081967213115, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=29.2181069958848, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=28.0851063829787, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.1285140562249, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI18859837, Length=231, Percent_Identity=28.1385281385281, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.0756972111554, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640442, Length=185, Percent_Identity=31.8918918918919, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649181, Length=185, Percent_Identity=28.6486486486486, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331216, Length=199, Percent_Identity=32.1608040201005, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24665247, Length=199, Percent_Identity=32.1608040201005, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641232, Length=232, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21356301, Length=225, Percent_Identity=28.4444444444444, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25985; Mature: 25985

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNLDSSAMNTHSHRRLAVVTGAGSGIGRAIALGLAAGGDRVVAADLDEASAAATAAEQPD
CCCCCCHHCCCCCCEEEEEECCCCCHHHHHHEEEECCCCEEEEECCCHHHHHHHHCCCCC
LITAAPVDVADPARVAALRDRIHADIGVPGVVVNAAGWDRTDQFLNATPEFAQKVVAINY
EEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCHHHHHHHHHEEC
LGPVHVCSAFLPGMIETHGGGRVVNVASDAGRVGSAGESIYAGAKGGVIALTKSLAREMA
CCHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
RHQITVNCVCPGPTDTPLFHAQPEKLKEALVKAIPLRRLARPEEVAAAVLFFASQAASFV
HCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TGQVISVSGGLTMAG
CCEEEEECCCEEECC
>Mature Secondary Structure
MNLDSSAMNTHSHRRLAVVTGAGSGIGRAIALGLAAGGDRVVAADLDEASAAATAAEQPD
CCCCCCHHCCCCCCEEEEEECCCCCHHHHHHEEEECCCCEEEEECCCHHHHHHHHCCCCC
LITAAPVDVADPARVAALRDRIHADIGVPGVVVNAAGWDRTDQFLNATPEFAQKVVAINY
EEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCHHHHHHHHHEEC
LGPVHVCSAFLPGMIETHGGGRVVNVASDAGRVGSAGESIYAGAKGGVIALTKSLAREMA
CCHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
RHQITVNCVCPGPTDTPLFHAQPEKLKEALVKAIPLRRLARPEEVAAAVLFFASQAASFV
HCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TGQVISVSGGLTMAG
CCEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]