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The map label for this gene is hypA

Identifier: 52842684

GI number: 52842684

Start: 2790860

End: 2791201

Strand: Reverse

Name: hypA

Synonym: lpg2476

Alternate gene names: 52842684

Gene position: 2791201-2790860 (Counterclockwise)

Preceding gene: 52842685

Following gene: 52842683

Centisome position: 82.15

GC content: 37.43

Gene sequence:

>342_bases
ATGCATGAATTATGGTTATGTAAGCGTATTGTCGAGATTATCAAGCAACAAGCCACTGGCAATAAATGCCGAAAGGTAAA
GAAAATAGTGCTGGAAATAGGGCAGCTAGTAGCAGTCGATAAGCACGCATTGAATTTTAGCTTTAAAGTGATAACTCAAG
GGACGATTGCACAAAATGCAGAATTATCGATTGTAGAAATCCCAGGTGAAGCAATATGCAATTCTTGTCAACAAATTGTA
CCGATGAAACAGTATTATGATGAATGCCTGGTTTGCGGCAATCATTCCTTAACACTGACAAAAGGTGAAGAATTAAAAGT
GAAATCAATGGTGGTGGAATAA

Upstream 100 bases:

>100_bases
TCTCATTACTTTTCTCAAGATTAGTAGGATTTGGCATTGCTTTTTTTAGCATAGGTATTGCTATAATCAATTGCTGCAAA
TTGCTTTAAACAGGCTAAAA

Downstream 100 bases:

>100_bases
TGTGCGGGATATGCGGATGTTCAGTAGAAAAAGGTCAAACCATGGATAATGGGCATCATGCTGCTCACCATGAGCATTCT
GTGCCTCATGAACATTCAGT

Product: hydrogenase nickel incorporation protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIV
PMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Sequences:

>Translated_113_residues
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIV
PMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
>Mature_113_residues
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIV
PMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=41.5929203539823, Blast_Score=93, Evalue=5e-21,
Organism=Escherichia coli, GI1789081, Length=114, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12686; Mature: 12686

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCC
ELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
CEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCEEHHEEECC
>Mature Secondary Structure
MHELWLCKRIVEIIKQQATGNKCRKVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCC
ELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
CEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCEEHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA