Click here to switch to the map view.

The map label for this gene is nixA [H]

Identifier: 52842685

GI number: 52842685

Start: 2791213

End: 2791980

Strand: Reverse

Name: nixA [H]

Synonym: lpg2477

Alternate gene names: 52842685

Gene position: 2791980-2791213 (Counterclockwise)

Preceding gene: 52842688

Following gene: 52842684

Centisome position: 82.17

GC content: 36.72

Gene sequence:

>768_bases
TTGGAAGTTGAGTCCATTGAGGGTTATAAAAACAGTGAAAGTATTGGTATATTGTCCATAGTCTTTAACATTAATAATGG
CCCCATACTAATGAACGATTCAGGTTGGTTTTTGATTTCAACTGCTCTCTTGCTTGGGATGCGTCATGGTTTTGATTTGG
ATCATCTGGCAACGATCGATGCGATAACTCGCACAGTTCGTTATAAACCTTCTTTATCGCGCATGGTTGGCTTTTTGTTT
TCACTAGGCCATGGTTTGGTAGTTATTATTGTGAGTTTGATCATTGGCGGGGGTATTATTTCAGCGAGTACTCCTGAATG
GTTAAATGAAGTGGGAAATATTGTATCAGTTACCTGTTTATTGTTATTTGGGTTTTTAACTTTGTGGAATACGGTTCATT
ATTCATCTTCTGCCATCATACCAACCAACTTAAGGAGTTATTTATTCAGGAAGCTTGCTGATAACAATGTACATCCTCTT
ATGATTCTTTTCATTGGTGCGTTGTTTGCCTTATCTTTTGATACGATGAGTCAAATTGTATTGTTTTCACTTGCAGCCAG
TGCTTTATCAGGTTTTCTATTTTCCGGGTTATTAGGTTTTGTTTTTATGCTGGGAATGATGATGTCGGATGGATTAAATG
GATTTTTTGTAGCAAGCTTGATTCGGCGTGCTGATGGGTTCTCATTACTTTTCTCAAGATTAGTAGGATTTGGCATTGCT
TTTTTTAGCATAGGTATTGCTATAATCAATTGCTGCAAATTGCTTTAA

Upstream 100 bases:

>100_bases
AACAACGCAAGAGATGAGTTTTTTATGTTTTGCAGTTTTAGACATAATGAGTATTAATGTACCATACAAAAGATAGATAG
CTTCATATGTTAACCTACTC

Downstream 100 bases:

>100_bases
ACAGGCTAAAAATGCATGAATTATGGTTATGTAAGCGTATTGTCGAGATTATCAAGCAACAAGCCACTGGCAATAAATGC
CGAAAGGTAAAGAAAATAGT

Product: high affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MEVESIEGYKNSESIGILSIVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYKPSLSRMVGFLF
SLGHGLVVIIVSLIIGGGIISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPL
MILFIGALFALSFDTMSQIVLFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIA
FFSIGIAIINCCKLL

Sequences:

>Translated_255_residues
MEVESIEGYKNSESIGILSIVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYKPSLSRMVGFLF
SLGHGLVVIIVSLIIGGGIISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPL
MILFIGALFALSFDTMSQIVLFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIA
FFSIGIAIINCCKLL
>Mature_255_residues
MEVESIEGYKNSESIGILSIVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATIDAITRTVRYKPSLSRMVGFLF
SLGHGLVVIIVSLIIGGGIISASTPEWLNEVGNIVSVTCLLLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPL
MILFIGALFALSFDTMSQIVLFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIA
FFSIGIAIINCCKLL

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 27742; Mature: 27742

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVESIEGYKNSESIGILSIVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATID
CCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHH
AITRTVRYKPSLSRMVGFLFSLGHGLVVIIVSLIIGGGIISASTPEWLNEVGNIVSVTCL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILFIGALFALSFDTMSQIV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FFSIGIAIINCCKLL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVESIEGYKNSESIGILSIVFNINNGPILMNDSGWFLISTALLLGMRHGFDLDHLATID
CCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHH
AITRTVRYKPSLSRMVGFLFSLGHGLVVIIVSLIIGGGIISASTPEWLNEVGNIVSVTCL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LLFGFLTLWNTVHYSSSAIIPTNLRSYLFRKLADNNVHPLMILFIGALFALSFDTMSQIV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LFSLAASALSGFLFSGLLGFVFMLGMMMSDGLNGFFVASLIRRADGFSLLFSRLVGFGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FFSIGIAIINCCKLL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]