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The map label for this gene is arsB [H]

Identifier: 39996512

GI number: 39996512

Start: 1549047

End: 1550042

Strand: Reverse

Name: arsB [H]

Synonym: GSU1411

Alternate gene names: 39996512

Gene position: 1550042-1549047 (Counterclockwise)

Preceding gene: 39996513

Following gene: 39996511

Centisome position: 40.64

GC content: 61.75

Gene sequence:

>996_bases
ATGTGGCAACTGCTGAGCAGACTCAACAAGAACCTGGTGCTGACCATTCCCGCCATGATGGCCGCGGGCTTCGTCTTCGG
TCTCGTGACTGAGACCGGCTTTCTCAAGGAGCTGATCATCCCCTTCACCTTTCTCATGGTCTACCCCATGATGGTGACCC
TTAAGCTGAAGAAGGTACTGGAGGGAGGTGACGGCAAGGCCCAGCTGTTCACCCAGTTCATCAACTTCGCGGTGGTGCCC
TTTGTCGCCTTCGGGCTGGGAAGGCTTTTCTTTGCTGACCGCCCCTACATGGCCCTGGGCCTGCTGCTTGCGGCCCTGGT
CCCCACCAGCGGCATGACCATCTCCTGGACCGGCTTTGCCAGGGGGAACCTCGAAGCGGCAGTCAAGATGACCGTCGTGG
GCCTCATCCTGGGCTCGATCGCAACCCCCTTCTACGTGCAAGCCCTCATGGGCGCCCATGTGGAGGTGGATATGACCGGC
ATCATGAAGCAAATCGCCGTCATCGTTTTCCTGCCCATGGCGGTCGGGTATGCGACCCAGCGCTATCTGATAGCGAAGCA
CGGCCAGAAAGGATTCCAGGAACAGTGGGCGCCCCGCTTCCCCTGCCTCTCCACCCTGGGCGTCCTGGGCATCGTTTTCA
TCGCCATAGCCCTCAAGGCACAGGCCATCGCGGCCCGCCCCCAGGATCTGCTGGCAATCCTGCTGCCCCTGGCCATTCTC
TACGGCATCAACTATAGCCTCAGCACCGTTGTGGGCAGGCTTTTCCTTCCCCGGGGCGATGCTATCGCCCTGGCCTACGG
CACGGTGATGCGCAACCTCTCCATTGCCCTGGCCGTGGCCATGAACGCCTTCGGCAAGGCCGGTTCCGACGCGGCGCTGG
TCATTGCCCTGGCCTACATCATCCAGGTGCAGTCAGCCGCCTGGTACGTAAAATTTACCGGCACGCTCTTCGGTGAGGCA
CCAGCGCCGTCCTGTCCCGCACCGAGGCGGAACTGA

Upstream 100 bases:

>100_bases
GTGGACGACACCGAGTTCGCCTCATCCCTGGATGAGAGCTTCGATGCCATCGTGGCCATGATCGAGGAGGCGCGCTGAGC
GCGCGCAGAGGGCCAAGGCT

Downstream 100 bases:

>100_bases
CCACCCGATGAAAGGAACCCATGTCGCCACGCAAGAAAAAACAACGCAACTGCATCTGCCCCCTCCGGGAGAAGCTGGGA
CACGTCTTCAAGCCCGCGGG

Product: sodium/bile acid symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MWQLLSRLNKNLVLTIPAMMAAGFVFGLVTETGFLKELIIPFTFLMVYPMMVTLKLKKVLEGGDGKAQLFTQFINFAVVP
FVAFGLGRLFFADRPYMALGLLLAALVPTSGMTISWTGFARGNLEAAVKMTVVGLILGSIATPFYVQALMGAHVEVDMTG
IMKQIAVIVFLPMAVGYATQRYLIAKHGQKGFQEQWAPRFPCLSTLGVLGIVFIAIALKAQAIAARPQDLLAILLPLAIL
YGINYSLSTVVGRLFLPRGDAIALAYGTVMRNLSIALAVAMNAFGKAGSDAALVIALAYIIQVQSAAWYVKFTGTLFGEA
PAPSCPAPRRN

Sequences:

>Translated_331_residues
MWQLLSRLNKNLVLTIPAMMAAGFVFGLVTETGFLKELIIPFTFLMVYPMMVTLKLKKVLEGGDGKAQLFTQFINFAVVP
FVAFGLGRLFFADRPYMALGLLLAALVPTSGMTISWTGFARGNLEAAVKMTVVGLILGSIATPFYVQALMGAHVEVDMTG
IMKQIAVIVFLPMAVGYATQRYLIAKHGQKGFQEQWAPRFPCLSTLGVLGIVFIAIALKAQAIAARPQDLLAILLPLAIL
YGINYSLSTVVGRLFLPRGDAIALAYGTVMRNLSIALAVAMNAFGKAGSDAALVIALAYIIQVQSAAWYVKFTGTLFGEA
PAPSCPAPRRN
>Mature_331_residues
MWQLLSRLNKNLVLTIPAMMAAGFVFGLVTETGFLKELIIPFTFLMVYPMMVTLKLKKVLEGGDGKAQLFTQFINFAVVP
FVAFGLGRLFFADRPYMALGLLLAALVPTSGMTISWTGFARGNLEAAVKMTVVGLILGSIATPFYVQALMGAHVEVDMTG
IMKQIAVIVFLPMAVGYATQRYLIAKHGQKGFQEQWAPRFPCLSTLGVLGIVFIAIALKAQAIAARPQDLLAILLPLAIL
YGINYSLSTVVGRLFLPRGDAIALAYGTVMRNLSIALAVAMNAFGKAGSDAALVIALAYIIQVQSAAWYVKFTGTLFGEA
PAPSCPAPRRN

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 35618; Mature: 35618

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQLLSRLNKNLVLTIPAMMAAGFVFGLVTETGFLKELIIPFTFLMVYPMMVTLKLKKVL
CHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGGDGKAQLFTQFINFAVVPFVAFGLGRLFFADRPYMALGLLLAALVPTSGMTISWTGFA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCC
RGNLEAAVKMTVVGLILGSIATPFYVQALMGAHVEVDMTGIMKQIAVIVFLPMAVGYATQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
RYLIAKHGQKGFQEQWAPRFPCLSTLGVLGIVFIAIALKAQAIAARPQDLLAILLPLAIL
HHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
YGINYSLSTVVGRLFLPRGDAIALAYGTVMRNLSIALAVAMNAFGKAGSDAALVIALAYI
HCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IQVQSAAWYVKFTGTLFGEAPAPSCPAPRRN
HHHHCCEEEEEEECEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MWQLLSRLNKNLVLTIPAMMAAGFVFGLVTETGFLKELIIPFTFLMVYPMMVTLKLKKVL
CHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGGDGKAQLFTQFINFAVVPFVAFGLGRLFFADRPYMALGLLLAALVPTSGMTISWTGFA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCC
RGNLEAAVKMTVVGLILGSIATPFYVQALMGAHVEVDMTGIMKQIAVIVFLPMAVGYATQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
RYLIAKHGQKGFQEQWAPRFPCLSTLGVLGIVFIAIALKAQAIAARPQDLLAILLPLAIL
HHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
YGINYSLSTVVGRLFLPRGDAIALAYGTVMRNLSIALAVAMNAFGKAGSDAALVIALAYI
HCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IQVQSAAWYVKFTGTLFGEAPAPSCPAPRRN
HHHHCCEEEEEEECEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]