Click here to switch to the map view.

The map label for this gene is pbp [H]

Identifier: 38234076

GI number: 38234076

Start: 1520073

End: 1521929

Strand: Reverse

Name: pbp [H]

Synonym: DIP1497

Alternate gene names: 38234076

Gene position: 1521929-1520073 (Counterclockwise)

Preceding gene: 38234077

Following gene: 38234075

Centisome position: 61.16

GC content: 51.1

Gene sequence:

>1857_bases
ATGGACATCGTCTCTGCTCGATTGGCTCGCCGTGCAACTGGAATCACCTTGGCTGTGTGCCTTGTAGGAAGCAGCTTGAC
GGCATGTACGCCAAAGCCTAAATCGGCACAACCTGTGGCGGAAGAATTCTTTCACAACGTAGCAGCACAAGATTTTGATG
CTGCAGCGCAGCTTACAGACCAAGATGATTCAGCCCGTGAATTGCTCTCACGATCGTGGGAAGGATTGCAGGCAGAAGGG
CTTGACGTATCCCTCAATAAGGTCGACGCCAAAGACACTGTAGCGACTGCGAAATACACGTTGACATGGAAACTGCCTAA
AGACCGCACATTGTCCTATGACACCTCTATGACGCTAAACCGAATTAACGATCAGTGGACAATTCGGTGGCAGCCTGCAG
CAGTACACCCCAAATTGGCTGCGAATCAGCACCTTGAACTACGTGCCATTAATGCCGAACGCGCAAGCGTTGTCTCATCC
GATGGGGCAGAGGTTCTCGTACCAGGAGTCCAGTATCGTTTGATCGCCGATACTCAACACATCATCGACAAAGCTGCTAC
GGCACAAACTATCGCAACGCACCTCCGCGCTGCTCGTGCAGCTGACGAGACGGTTCCAGAGCTATCTGCCAGCGACATTC
AGCAGGCATTAGAAACCAATCGTGGTTCATATTCACTCGCAGTGGTTAACGAGCGTGCAGGCGACAGTATAAAACAGGCG
CTGGCAGGAGTATCGGGAATCCGACTTAATAAAGAGGCTGCGATGGTTAACAAAGACCCCAACTTCGCACCTGATGTCAT
TCGGCGGGTGTCGTCGTTAGTGAACGACCAACTGGCAGGAGCAAATGGTTGGAGTGTCGACGCAGTCACGCAAGACGGTG
TCTCCATGCAAACCATCGAAAGGCATGCTCCTCAGGTTGCGCCAGCAATTCGCATCAGCTTGAACCACAATGTGCAAGTT
GCTGCGGAACGTGCCGTCAATCTTCGCAAAGACAAACAATCCATGCTGGTAGCGATTCGGCCATCAACAGGCGAAATTCT
AGCTATTGCACAGTCAGATCTAGCAGATAAACAAGGCGACCTAGCACTCAACGGACAGTATCCGCCAGGATCTACTTTTA
AGATCGTAACAGCATCTGCTGGTATCCAAGATCAAGGTCTAAACGCGGATTCAATCGTGCCATGCCCTGGAACTATGAAC
ATCTATGGCCGAACAGTAACCAATTACAACGGCTTCTCCCTAGGAAACGTTCCGCTAGAAAAAGCATTCGCACGATCCTG
CAACACCACATTTGCCAACATTTCAGAGCAACTTAACAAAGGACAACTCAAAGAAATCGGTCGCGATTTTGGGATCGGAA
TCGATTACGACATTCCAGGGCTTAATACTCTTACCGGTTCCATCCCACAGGGAGATACTGAACTTGCACGAACGGAAGCC
GGTTATGGTCAGGGCGAAGTGCTCGTAAGCCCATTTGGAATGGCTTTAGTATCGGCGACCGCTGCGGCAGGAAAGACCCC
AACACCAACGCTCGTTTCTGGCACTACAACAAAGGTTTCTGGAACCGCAGATGGCCTCAAACCAGAAACTGTTGAGCAGC
TACGACGTCTCATGGGTGCTGTGACCGCGCCGGGCGGCACTGCAGCAGGTATGCGTGCCGGAGGCAAGATTTTCGGCAAG
ACTGGTGAGGCTGAAATCAATGGGGGATCCCACGCATGGTTTACCGGATATAGGGATGACATCGCGTTTGCAAGTTTGGT
TGTTTTAGGCGGTGGTTCGGAAGCCTCAGTTGCTGTAGTGGATAACTTTTTCACTACTCTTGATGATCTCAACGCAGGTA
TTGCAGTATCGGAGTAG

Upstream 100 bases:

>100_bases
GGTTTCAAGGGTGCATCGGAATATTTCCGTGCACCCTTTCTTATTTGAGCTCGGGCGTTGCACAATAGAGTGACGTCACG
CCAGTGTTAGCCTTGTCGCC

Downstream 100 bases:

>100_bases
TACCCCGTTGGTACCGGCAAAGCCTTATTAGGGTTAGCATAGTTTTATGGCTATTACTCGAGAACCTTTAAAACCTGGAC
ATCCCACCCCGATTCGTGAG

Product: putative secreted penicillin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MDIVSARLARRATGITLAVCLVGSSLTACTPKPKSAQPVAEEFFHNVAAQDFDAAAQLTDQDDSARELLSRSWEGLQAEG
LDVSLNKVDAKDTVATAKYTLTWKLPKDRTLSYDTSMTLNRINDQWTIRWQPAAVHPKLAANQHLELRAINAERASVVSS
DGAEVLVPGVQYRLIADTQHIIDKAATAQTIATHLRAARAADETVPELSASDIQQALETNRGSYSLAVVNERAGDSIKQA
LAGVSGIRLNKEAAMVNKDPNFAPDVIRRVSSLVNDQLAGANGWSVDAVTQDGVSMQTIERHAPQVAPAIRISLNHNVQV
AAERAVNLRKDKQSMLVAIRPSTGEILAIAQSDLADKQGDLALNGQYPPGSTFKIVTASAGIQDQGLNADSIVPCPGTMN
IYGRTVTNYNGFSLGNVPLEKAFARSCNTTFANISEQLNKGQLKEIGRDFGIGIDYDIPGLNTLTGSIPQGDTELARTEA
GYGQGEVLVSPFGMALVSATAAAGKTPTPTLVSGTTTKVSGTADGLKPETVEQLRRLMGAVTAPGGTAAGMRAGGKIFGK
TGEAEINGGSHAWFTGYRDDIAFASLVVLGGGSEASVAVVDNFFTTLDDLNAGIAVSE

Sequences:

>Translated_618_residues
MDIVSARLARRATGITLAVCLVGSSLTACTPKPKSAQPVAEEFFHNVAAQDFDAAAQLTDQDDSARELLSRSWEGLQAEG
LDVSLNKVDAKDTVATAKYTLTWKLPKDRTLSYDTSMTLNRINDQWTIRWQPAAVHPKLAANQHLELRAINAERASVVSS
DGAEVLVPGVQYRLIADTQHIIDKAATAQTIATHLRAARAADETVPELSASDIQQALETNRGSYSLAVVNERAGDSIKQA
LAGVSGIRLNKEAAMVNKDPNFAPDVIRRVSSLVNDQLAGANGWSVDAVTQDGVSMQTIERHAPQVAPAIRISLNHNVQV
AAERAVNLRKDKQSMLVAIRPSTGEILAIAQSDLADKQGDLALNGQYPPGSTFKIVTASAGIQDQGLNADSIVPCPGTMN
IYGRTVTNYNGFSLGNVPLEKAFARSCNTTFANISEQLNKGQLKEIGRDFGIGIDYDIPGLNTLTGSIPQGDTELARTEA
GYGQGEVLVSPFGMALVSATAAAGKTPTPTLVSGTTTKVSGTADGLKPETVEQLRRLMGAVTAPGGTAAGMRAGGKIFGK
TGEAEINGGSHAWFTGYRDDIAFASLVVLGGGSEASVAVVDNFFTTLDDLNAGIAVSE
>Mature_618_residues
MDIVSARLARRATGITLAVCLVGSSLTACTPKPKSAQPVAEEFFHNVAAQDFDAAAQLTDQDDSARELLSRSWEGLQAEG
LDVSLNKVDAKDTVATAKYTLTWKLPKDRTLSYDTSMTLNRINDQWTIRWQPAAVHPKLAANQHLELRAINAERASVVSS
DGAEVLVPGVQYRLIADTQHIIDKAATAQTIATHLRAARAADETVPELSASDIQQALETNRGSYSLAVVNERAGDSIKQA
LAGVSGIRLNKEAAMVNKDPNFAPDVIRRVSSLVNDQLAGANGWSVDAVTQDGVSMQTIERHAPQVAPAIRISLNHNVQV
AAERAVNLRKDKQSMLVAIRPSTGEILAIAQSDLADKQGDLALNGQYPPGSTFKIVTASAGIQDQGLNADSIVPCPGTMN
IYGRTVTNYNGFSLGNVPLEKAFARSCNTTFANISEQLNKGQLKEIGRDFGIGIDYDIPGLNTLTGSIPQGDTELARTEA
GYGQGEVLVSPFGMALVSATAAAGKTPTPTLVSGTTTKVSGTADGLKPETVEQLRRLMGAVTAPGGTAAGMRAGGKIFGK
TGEAEINGGSHAWFTGYRDDIAFASLVVLGGGSEASVAVVDNFFTTLDDLNAGIAVSE

Specific function: Cell Wall Formation. Essential For The Formation Of A Septum Of The Murein Sacculus. Synthesis Of Cross-Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR007887
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF05223 MecA_N; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65138; Mature: 65138

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVSARLARRATGITLAVCLVGSSLTACTPKPKSAQPVAEEFFHNVAAQDFDAAAQLTD
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCC
QDDSARELLSRSWEGLQAEGLDVSLNKVDAKDTVATAKYTLTWKLPKDRTLSYDTSMTLN
CCHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHEEEEEEEEEEECCCCCEEECCCCEEEE
RINDQWTIRWQPAAVHPKLAANQHLELRAINAERASVVSSDGAEVLVPGVQYRLIADTQH
CCCCEEEEEEECCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCEEEECCCEEEEEECHHH
IIDKAATAQTIATHLRAARAADETVPELSASDIQQALETNRGSYSLAVVNERAGDSIKQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
LAGVSGIRLNKEAAMVNKDPNFAPDVIRRVSSLVNDQLAGANGWSVDAVTQDGVSMQTIE
HCCCCCEEECCCHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
RHAPQVAPAIRISLNHNVQVAAERAVNLRKDKQSMLVAIRPSTGEILAIAQSDLADKQGD
HCCCCCCCEEEEEECCCEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCC
LALNGQYPPGSTFKIVTASAGIQDQGLNADSIVPCPGTMNIYGRTVTNYNGFSLGNVPLE
EEECCCCCCCCEEEEEEECCCCCCCCCCCCCEECCCCCCEECEEEEECCCCEEECCCCHH
KAFARSCNTTFANISEQLNKGQLKEIGRDFGIGIDYDIPGLNTLTGSIPQGDTELARTEA
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCC
GYGQGEVLVSPFGMALVSATAAAGKTPTPTLVSGTTTKVSGTADGLKPETVEQLRRLMGA
CCCCCCEEECCHHHHHHHHHHHCCCCCCCCEECCCCEEECCCCCCCCHHHHHHHHHHHHH
VTAPGGTAAGMRAGGKIFGKTGEAEINGGSHAWFTGYRDDIAFASLVVLGGGSEASVAVV
CCCCCCCCCCCCCCCEEECCCCCEEECCCCEEEECCCCHHHHEEEEEEEECCCCCEEEEH
DNFFTTLDDLNAGIAVSE
HHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MDIVSARLARRATGITLAVCLVGSSLTACTPKPKSAQPVAEEFFHNVAAQDFDAAAQLTD
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCC
QDDSARELLSRSWEGLQAEGLDVSLNKVDAKDTVATAKYTLTWKLPKDRTLSYDTSMTLN
CCHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHEEEEEEEEEEECCCCCEEECCCCEEEE
RINDQWTIRWQPAAVHPKLAANQHLELRAINAERASVVSSDGAEVLVPGVQYRLIADTQH
CCCCEEEEEEECCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCEEEECCCEEEEEECHHH
IIDKAATAQTIATHLRAARAADETVPELSASDIQQALETNRGSYSLAVVNERAGDSIKQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
LAGVSGIRLNKEAAMVNKDPNFAPDVIRRVSSLVNDQLAGANGWSVDAVTQDGVSMQTIE
HCCCCCEEECCCHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
RHAPQVAPAIRISLNHNVQVAAERAVNLRKDKQSMLVAIRPSTGEILAIAQSDLADKQGD
HCCCCCCCEEEEEECCCEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCC
LALNGQYPPGSTFKIVTASAGIQDQGLNADSIVPCPGTMNIYGRTVTNYNGFSLGNVPLE
EEECCCCCCCCEEEEEEECCCCCCCCCCCCCEECCCCCCEECEEEEECCCCEEECCCCHH
KAFARSCNTTFANISEQLNKGQLKEIGRDFGIGIDYDIPGLNTLTGSIPQGDTELARTEA
HHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCC
GYGQGEVLVSPFGMALVSATAAAGKTPTPTLVSGTTTKVSGTADGLKPETVEQLRRLMGA
CCCCCCEEECCHHHHHHHHHHHCCCCCCCCEECCCCEEECCCCCCCCHHHHHHHHHHHHH
VTAPGGTAAGMRAGGKIFGKTGEAEINGGSHAWFTGYRDDIAFASLVVLGGGSEASVAVV
CCCCCCCCCCCCCCCEEECCCCCEEECCCCEEEECCCCHHHHEEEEEEEECCCCCEEEEH
DNFFTTLDDLNAGIAVSE
HHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3305073 [H]