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The map label for this gene is dapB

Identifier: 38234047

GI number: 38234047

Start: 1485381

End: 1486127

Strand: Reverse

Name: dapB

Synonym: DIP1466

Alternate gene names: 38234047

Gene position: 1486127-1485381 (Counterclockwise)

Preceding gene: 38234048

Following gene: 38234046

Centisome position: 59.72

GC content: 49.8

Gene sequence:

>747_bases
ATGGCGATCAAAGTAGGCGTATTAGGAGCCCAAGGCCGAGTCGGACAAGCAATTGTCGCCGGTGTAACGGCGGCTTATGA
TTTGGAACTTGTTGCTGAGGTTGATCGCGGCGATAGTCTTGATGTGCTTGTGCAATCGGGAGCGGAAGTTATCGTCGATT
TCACAACTCCTGACTCCGTCATGGACAATCTAGAGTTCTGTATTTCACACGGAATTCATTGCGTCGTGGGAACCACAGGT
TTTACTCCTGAGCGTTTAGAAATCGTCAAAAAATGGGCGGAAGAAAAGGGCAACACTGGTGTTCTTATTGCGCCGAATTT
TGCTATTTCAGCTGTTCTCACTATGGCTTTTGCTCGTCAAGCAGCTCGATTCTTCGATTCCGCAGAAGTAGTGGAATGCC
ATCACCCTAATAAATTGGATGCGCCATCAGGCACCGCTATTCACACAGCTGAAGGTATTGCGCAGGCGCGTCGTGAAGCC
GGAATGCCAACACAGCCTGATGCCACCGAACAATCTCTTGACGGTGCGCGCGGTGCAGATGTTGGTGGTGTGAAAGTCCA
CGCGGTAAGGATGACCGGAATGGTAGCTCATGAAGAAGTAATTTTTGGTGGTCCTGGTCAATCGCTAACGATTCGCCAAG
ATTCTTACGATCGAACCTCTTTTGTGCCAGGCGTATTGGTCGGAGTGCGAAATGTTGCTCAGCATCTCGGTCTTACGGTC
GGACTTGAGCACTACTTGGACATCTAA

Upstream 100 bases:

>100_bases
TTGAGTATTTCTGTGTCGTTGTAGACTGGAATGCATTCGTGTGTGATGCATGCGCTCATGCTGAGGCGACCGATAATTTT
AAGGATAGGAAGAGGAGAAT

Downstream 100 bases:

>100_bases
TGGCACAGCAGTCTTTGCTTGATGTTCAGCTGGTGGCATGTAGTACTTTTACTACGCCATCTGGGGTCGACTGGAAAGTG
GATTCCGCAGCAACAGATTC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MAIKVGVLGAQGRVGQAIVAGVTAAYDLELVAEVDRGDSLDVLVQSGAEVIVDFTTPDSVMDNLEFCISHGIHCVVGTTG
FTPERLEIVKKWAEEKGNTGVLIAPNFAISAVLTMAFARQAARFFDSAEVVECHHPNKLDAPSGTAIHTAEGIAQARREA
GMPTQPDATEQSLDGARGADVGGVKVHAVRMTGMVAHEEVIFGGPGQSLTIRQDSYDRTSFVPGVLVGVRNVAQHLGLTV
GLEHYLDI

Sequences:

>Translated_248_residues
MAIKVGVLGAQGRVGQAIVAGVTAAYDLELVAEVDRGDSLDVLVQSGAEVIVDFTTPDSVMDNLEFCISHGIHCVVGTTG
FTPERLEIVKKWAEEKGNTGVLIAPNFAISAVLTMAFARQAARFFDSAEVVECHHPNKLDAPSGTAIHTAEGIAQARREA
GMPTQPDATEQSLDGARGADVGGVKVHAVRMTGMVAHEEVIFGGPGQSLTIRQDSYDRTSFVPGVLVGVRNVAQHLGLTV
GLEHYLDI
>Mature_247_residues
AIKVGVLGAQGRVGQAIVAGVTAAYDLELVAEVDRGDSLDVLVQSGAEVIVDFTTPDSVMDNLEFCISHGIHCVVGTTGF
TPERLEIVKKWAEEKGNTGVLIAPNFAISAVLTMAFARQAARFFDSAEVVECHHPNKLDAPSGTAIHTAEGIAQARREAG
MPTQPDATEQSLDGARGADVGGVKVHAVRMTGMVAHEEVIFGGPGQSLTIRQDSYDRTSFVPGVLVGVRNVAQHLGLTVG
LEHYLDI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CORDI (Q6NGP2)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939814.1
- ProteinModelPortal:   Q6NGP2
- SMR:   Q6NGP2
- GeneID:   2650351
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1466
- NMPDR:   fig|257309.1.peg.1405
- HOGENOM:   HBG594002
- OMA:   ARFYDHA
- ProtClustDB:   PRK00048
- BioCyc:   CDIP257309:DIP1466-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26156; Mature: 26025

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVGVLGAQGRVGQAIVAGVTAAYDLELVAEVDRGDSLDVLVQSGAEVIVDFTTPDSV
CEEEEEEECCCCCCCHHHHHHHHHHHCEEEEEECCCCCCHHHEECCCCEEEEEECCCHHH
MDNLEFCISHGIHCVVGTTGFTPERLEIVKKWAEEKGNTGVLIAPNFAISAVLTMAFARQ
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
AARFFDSAEVVECHHPNKLDAPSGTAIHTAEGIAQARREAGMPTQPDATEQSLDGARGAD
HHHHCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
VGGVKVHAVRMTGMVAHEEVIFGGPGQSLTIRQDSYDRTSFVPGVLVGVRNVAQHLGLTV
CCCEEEEEEEEECEEEECEEEECCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHCCHHC
GLEHYLDI
CHHHHHCC
>Mature Secondary Structure 
AIKVGVLGAQGRVGQAIVAGVTAAYDLELVAEVDRGDSLDVLVQSGAEVIVDFTTPDSV
EEEEEEECCCCCCCHHHHHHHHHHHCEEEEEECCCCCCHHHEECCCCEEEEEECCCHHH
MDNLEFCISHGIHCVVGTTGFTPERLEIVKKWAEEKGNTGVLIAPNFAISAVLTMAFARQ
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
AARFFDSAEVVECHHPNKLDAPSGTAIHTAEGIAQARREAGMPTQPDATEQSLDGARGAD
HHHHCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
VGGVKVHAVRMTGMVAHEEVIFGGPGQSLTIRQDSYDRTSFVPGVLVGVRNVAQHLGLTV
CCCEEEEEEEEECEEEECEEEECCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHCCHHC
GLEHYLDI
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910