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The map label for this gene is ribD [H]

Identifier: 38233905

GI number: 38233905

Start: 1330722

End: 1331726

Strand: Reverse

Name: ribD [H]

Synonym: DIP1319

Alternate gene names: 38233905

Gene position: 1331726-1330722 (Counterclockwise)

Preceding gene: 38233906

Following gene: 38233904

Centisome position: 53.51

GC content: 47.86

Gene sequence:

>1005_bases
ATGAACTTTATTTATCCTGCGGTCATTGCAGCAGTTCAAGAAGGAGAAAAGGCTTGGGGAACTACACACCCTAACCCTCC
GGTTGGGGCAGTGGTGCTGTCTAGCAATGGCTCGATTGTGGGAAGGGGGCATACCCAACCACCTGGGGGCTCTCACGCTG
AAATAATGGCATTGAGGCAGGCAGGGGAGAATACAAAAGGTGGCACATTAGTGGTCACTTTAGAGCCATGTAATCACTGG
GGAAGAACTGGTCCCTGCAGTCATGCTATTTCTGAATCCGGTATTGAGCACGTAGTTTATCTCATGCAAGATACCGGTTC
GCTAGAGAAAGGCGGGGCGGAATATCTTCGGCGCCAAGGATTAAAGGTGACCTTTTTAGGCCTCAGTGTTGCTGCTCTTA
TTCCTTGGCAAGCATCTAAAGATCGTGGTTGGCCGTATGTTGTAGGGAAAACTGCCCACACTCTGGATGGCTTTGTTGCT
GCTGAAGACCACAGCTCCAAATGGATAACTGGCAGTGCATCGCGTGATTACGCCAATCGGCAACGACGGCATTTTGATGC
GATCATTGTTGGAACTGGCACTGTCAAAGCTGATAATCCAGCTTTGACAGCTCGAAAAGACGATGGCACCTTATTGCCGC
ATCAACCGCTCAAAGTGGTCATCGGAACGAGTAAAATTTCTGAGGGTACGCAGTTAGCACGATCGGGATTTGTGCAGTTT
TCAACGATCGAAGAAGCATTGGTACAACTTTGGGACCGAGGGGTGCGTTATGTGCTGGTTGAAGGCGGTCCACATTTATT
ACATGGTTTTTTAACGAGCGGTAATCTCGACCAGTTACATTCGTATAGTGCGCCCATGCTTTTAACTCGAGGAGTTTCCC
TTCTACAAGAGGAGGAGAAGAAATCTGCGGAAAGTGCTAATACTACGATTGCAAGTGCATTAAGAGGAAGTCCTCAATCC
ATTTCGATGCTCGGGGACGATATTCTTCAAGTAATTAATATTTGA

Upstream 100 bases:

>100_bases
GCCTAGACAGAAAGACATGCAGGTGAATTGTGGGGTGCCGCTTAGTGCTGAGTTGCCGTTAAACACCATTTATGCGGAAA
CTACGGTTATTGGCACTGAA

Downstream 100 bases:

>100_bases
TCTGAACACCGAGTGGTTGTGACGAAATCTCATCGAAAAAATAAAAGGATTAGCAAAATGTTTACTGGGTTAATAGAAGA
AATCGGAACGATTACTGGAA

Product: putative riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNFIYPAVIAAVQEGEKAWGTTHPNPPVGAVVLSSNGSIVGRGHTQPPGGSHAEIMALRQAGENTKGGTLVVTLEPCNHW
GRTGPCSHAISESGIEHVVYLMQDTGSLEKGGAEYLRRQGLKVTFLGLSVAALIPWQASKDRGWPYVVGKTAHTLDGFVA
AEDHSSKWITGSASRDYANRQRRHFDAIIVGTGTVKADNPALTARKDDGTLLPHQPLKVVIGTSKISEGTQLARSGFVQF
STIEEALVQLWDRGVRYVLVEGGPHLLHGFLTSGNLDQLHSYSAPMLLTRGVSLLQEEEKKSAESANTTIASALRGSPQS
ISMLGDDILQVINI

Sequences:

>Translated_334_residues
MNFIYPAVIAAVQEGEKAWGTTHPNPPVGAVVLSSNGSIVGRGHTQPPGGSHAEIMALRQAGENTKGGTLVVTLEPCNHW
GRTGPCSHAISESGIEHVVYLMQDTGSLEKGGAEYLRRQGLKVTFLGLSVAALIPWQASKDRGWPYVVGKTAHTLDGFVA
AEDHSSKWITGSASRDYANRQRRHFDAIIVGTGTVKADNPALTARKDDGTLLPHQPLKVVIGTSKISEGTQLARSGFVQF
STIEEALVQLWDRGVRYVLVEGGPHLLHGFLTSGNLDQLHSYSAPMLLTRGVSLLQEEEKKSAESANTTIASALRGSPQS
ISMLGDDILQVINI
>Mature_334_residues
MNFIYPAVIAAVQEGEKAWGTTHPNPPVGAVVLSSNGSIVGRGHTQPPGGSHAEIMALRQAGENTKGGTLVVTLEPCNHW
GRTGPCSHAISESGIEHVVYLMQDTGSLEKGGAEYLRRQGLKVTFLGLSVAALIPWQASKDRGWPYVVGKTAHTLDGFVA
AEDHSSKWITGSASRDYANRQRRHFDAIIVGTGTVKADNPALTARKDDGTLLPHQPLKVVIGTSKISEGTQLARSGFVQF
STIEEALVQLWDRGVRYVLVEGGPHLLHGFLTSGNLDQLHSYSAPMLLTRGVSLLQEEEKKSAESANTTIASALRGSPQS
ISMLGDDILQVINI

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=333, Percent_Identity=33.9339339339339, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 35727; Mature: 35727

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIYPAVIAAVQEGEKAWGTTHPNPPVGAVVLSSNGSIVGRGHTQPPGGSHAEIMALRQ
CCCHHHHHHHHHHCCHHHCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHH
AGENTKGGTLVVTLEPCNHWGRTGPCSHAISESGIEHVVYLMQDTGSLEKGGAEYLRRQG
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCCHHEEEEEEECCCCCCCCCHHHHHHCC
LKVTFLGLSVAALIPWQASKDRGWPYVVGKTAHTLDGFVAAEDHSSKWITGSASRDYANR
CEEEEEEEEEEHHCCCCCCCCCCCCEEECCCCHHHCCEEEECCCCCCEEECCCCHHHHHH
QRRHFDAIIVGTGTVKADNPALTARKDDGTLLPHQPLKVVIGTSKISEGTQLARSGFVQF
HHHCEEEEEEECCEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCEEH
STIEEALVQLWDRGVRYVLVEGGPHLLHGFLTSGNLDQLHSYSAPMLLTRGVSLLQEEEK
HHHHHHHHHHHHCCCEEEEEECCHHHEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHH
KSAESANTTIASALRGSPQSISMLGDDILQVINI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFIYPAVIAAVQEGEKAWGTTHPNPPVGAVVLSSNGSIVGRGHTQPPGGSHAEIMALRQ
CCCHHHHHHHHHHCCHHHCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHH
AGENTKGGTLVVTLEPCNHWGRTGPCSHAISESGIEHVVYLMQDTGSLEKGGAEYLRRQG
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHCCHHEEEEEEECCCCCCCCCHHHHHHCC
LKVTFLGLSVAALIPWQASKDRGWPYVVGKTAHTLDGFVAAEDHSSKWITGSASRDYANR
CEEEEEEEEEEHHCCCCCCCCCCCCEEECCCCHHHCCEEEECCCCCCEEECCCCHHHHHH
QRRHFDAIIVGTGTVKADNPALTARKDDGTLLPHQPLKVVIGTSKISEGTQLARSGFVQF
HHHCEEEEEEECCEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCEEH
STIEEALVQLWDRGVRYVLVEGGPHLLHGFLTSGNLDQLHSYSAPMLLTRGVSLLQEEEK
HHHHHHHHHHHHCCCEEEEEECCHHHEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHH
KSAESANTTIASALRGSPQSISMLGDDILQVINI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA