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The map label for this gene is rpe [H]

Identifier: 38233906

GI number: 38233906

Start: 1331821

End: 1332495

Strand: Reverse

Name: rpe [H]

Synonym: DIP1320

Alternate gene names: 38233906

Gene position: 1332495-1331821 (Counterclockwise)

Preceding gene: 38233907

Following gene: 38233905

Centisome position: 53.54

GC content: 45.48

Gene sequence:

>675_bases
ATGACTCAGACTCGACAGTGTCCGATTATTGCACCATCAATTTTAGCTGCAGATTTTCGTAAGCTTGAAGAAGAAATCCA
GTCGGTTAACCATGCCGACTGGATTCATGTCGATGTGATGGACGGTCACTTTGTGCCAAATCTTTCTTTTGGGGCAGATA
TCACTTGTGCTGCACGGTTGAGTACCTCACAACCACTTGACGTTCATCTAATGATCGAAAATCCAGAAAATTGGGTGGAT
TCGTACATTAAAGCTGGTGCGTTTACTGTCATATTTCATGTGGAAGCAACAGACAACCCAGTAGATCTTGCACGACATAT
TAGAGAACAGGGCGCAAGAGCAGGGTTTTCGTTAAAACCAAGTACTCCGATTGATCCTTATCTCGATATGCTAGAAGAGT
TTGACGAAGTTTTGATCATGAGTGTCGAACCTGGTTTCGGCGGACAAAAATTTATGCCGGAGCAATTAGAGAAGGTCCGT
CAACTTCGTCGAATTATTGATGAACGCAATCTAGACGTGACTATCGAAATTGACGGTGGTATTTCAGAGTCCACAATCCG
CCAAGCTGCAGAAGCAGGGTGTGATGCCTTTGTTGCCGGTTCTGCTGTCTTTGGTAGTGATGACCGTAATGCTGCCATTG
ACGCATTACGCGAACGTGCGCGCAGTCGTGCCTAG

Upstream 100 bases:

>100_bases
GACATGGCACAGATGCGATGTTTTTCGCAGTGCTGCGTAAAAAATAACGAGATGGGGTAGCGTCGCGTCGAGCTTATGGT
TTCCACGCTAGACTGAGGCT

Downstream 100 bases:

>100_bases
ACAGAAAGACATGCAGGTGAATTGTGGGGTGCCGCTTAGTGCTGAGTTGCCGTTAAACACCATTTATGCGGAAACTACGG
TTATTGGCACTGAAATGAAC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTQTRQCPIIAPSILAADFRKLEEEIQSVNHADWIHVDVMDGHFVPNLSFGADITCAARLSTSQPLDVHLMIENPENWVD
SYIKAGAFTVIFHVEATDNPVDLARHIREQGARAGFSLKPSTPIDPYLDMLEEFDEVLIMSVEPGFGGQKFMPEQLEKVR
QLRRIIDERNLDVTIEIDGGISESTIRQAAEAGCDAFVAGSAVFGSDDRNAAIDALRERARSRA

Sequences:

>Translated_224_residues
MTQTRQCPIIAPSILAADFRKLEEEIQSVNHADWIHVDVMDGHFVPNLSFGADITCAARLSTSQPLDVHLMIENPENWVD
SYIKAGAFTVIFHVEATDNPVDLARHIREQGARAGFSLKPSTPIDPYLDMLEEFDEVLIMSVEPGFGGQKFMPEQLEKVR
QLRRIIDERNLDVTIEIDGGISESTIRQAAEAGCDAFVAGSAVFGSDDRNAAIDALRERARSRA
>Mature_223_residues
TQTRQCPIIAPSILAADFRKLEEEIQSVNHADWIHVDVMDGHFVPNLSFGADITCAARLSTSQPLDVHLMIENPENWVDS
YIKAGAFTVIFHVEATDNPVDLARHIREQGARAGFSLKPSTPIDPYLDMLEEFDEVLIMSVEPGFGGQKFMPEQLEKVRQ
LRRIIDERNLDVTIEIDGGISESTIRQAAEAGCDAFVAGSAVFGSDDRNAAIDALRERARSRA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=223, Percent_Identity=40.8071748878924, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI219879828, Length=223, Percent_Identity=40.3587443946188, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI24307923, Length=179, Percent_Identity=37.4301675977654, Blast_Score=118, Evalue=5e-27,
Organism=Escherichia coli, GI1789788, Length=213, Percent_Identity=43.1924882629108, Blast_Score=178, Evalue=2e-46,
Organism=Escherichia coli, GI1790523, Length=195, Percent_Identity=33.8461538461538, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=31.4009661835749, Blast_Score=114, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=42.8571428571429, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6322341, Length=235, Percent_Identity=42.5531914893617, Blast_Score=191, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24586301, Length=216, Percent_Identity=41.6666666666667, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24837; Mature: 24706

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTRQCPIIAPSILAADFRKLEEEIQSVNHADWIHVDVMDGHFVPNLSFGADITCAARL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEC
STSQPLDVHLMIENPENWVDSYIKAGAFTVIFHVEATDNPVDLARHIREQGARAGFSLKP
CCCCCCEEEEEEECCHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCC
STPIDPYLDMLEEFDEVLIMSVEPGFGGQKFMPEQLEKVRQLRRIIDERNLDVTIEIDGG
CCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCC
ISESTIRQAAEAGCDAFVAGSAVFGSDDRNAAIDALRERARSRA
CCHHHHHHHHHHCCCEEEECCEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTRQCPIIAPSILAADFRKLEEEIQSVNHADWIHVDVMDGHFVPNLSFGADITCAARL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEC
STSQPLDVHLMIENPENWVDSYIKAGAFTVIFHVEATDNPVDLARHIREQGARAGFSLKP
CCCCCCEEEEEEECCHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCC
STPIDPYLDMLEEFDEVLIMSVEPGFGGQKFMPEQLEKVRQLRRIIDERNLDVTIEIDGG
CCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCC
ISESTIRQAAEAGCDAFVAGSAVFGSDDRNAAIDALRERARSRA
CCHHHHHHHHHHCCCEEEECCEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]