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The map label for this gene is cobL [H]

Identifier: 38233824

GI number: 38233824

Start: 1237585

End: 1238832

Strand: Reverse

Name: cobL [H]

Synonym: DIP1236

Alternate gene names: 38233824

Gene position: 1238832-1237585 (Counterclockwise)

Preceding gene: 38233825

Following gene: 38233823

Centisome position: 49.78

GC content: 52.8

Gene sequence:

>1248_bases
TTGGGACGCTCCAAAAACGACGATGGCCAAGCACACACCGGTAGCATTACCGTCGTCGGAATTGGAGCTGGCGGTGTAGA
AGAACTCGGTGCACAAGCTCGCACCGCACTACGCCAAGCCACAATCATCATCGGATCCAAACGCCAACTCGGACTGCTCC
CCGAAGATTTCCAAGGCGACCGAATCGCATGGCCATCTCCGCTTGTTCCAGCAATCCCAGCACTCTTCGCTGAATTCATC
GACAAAGAAGTCGTAGTCCTTGGATCCGGTGACCCCATGTTTCACGGTATCGGCAGCACACTCCACCGACTGCTTCCAAA
TCACAGCATGACCGTGATTCCGCAGCCATCATCGGCATCGCTAGCATGTGCTCGACTCGGTTGGGCACTAGATACAACAA
GCGTCTACAGCCTCGTCACCCATCCCATCGCACATCTCACATTAGCAATCGAACAAGGTGACCGTTTCCTAGTATTAGGA
CGCAACCATGAGTCTCCACACGAGATCTGTGAACACCTTATTTCTTTAGGTCAAAGCACCGCAGAAGTAACCGTTCTGAG
CGATATCGGCAGCGTTAGCGAAACAATTACTTCAGGAGCAGCTACTGACTACCCGTCGAACGATTCAGCATTGAACGTTA
TCGCGATACGCCCACTCGCCGCCACCCGAAGTAGAGTACCGGGACTACCAGACTCCGAGTACGTCACCGATGGTCAGCTC
ACAAAACAACACGTCCGAGCACTCGCGATATCAGCTTTGGCTCCTAAACCTCATGAAACTCTGTGGGATATCGGAGGCGG
ATCCGGTTCCATCGCTATCGAATGGCTGCGTTCAACACCACAAACGACAGCTGTCTGCTTCGAAATATCGGAAGAACGTC
GCGAACGAATCCTCAGCAATGCAATCAACCTCGGGGTATCCGATAGGATAGCAGTGCAGCAAGGCGCCCCCAGAGCATTT
GACGATGTTCCAGACAACCCCGACGTCATCTTCATCGGCGGTGGACTTACCGCGCCGGGCGTGTTCGCGGCCGCATGGAA
ACGCCTACCAGTAGGGGGTCGATTAGTAGCCAACGCAGTGACAGTAGAAAGCGAACAAATGCTTTGGGCACTGCGTAAAC
AATTTGGTGGAACTATCAGTTCGTTTGCTATTTCGCATGAGCACACAGTGGGCTCATTCATCACCATGAAACCTGCATTA
CCGGTACACCAATGGACCGTAGTAAAAGCATTGACAAAGGAACTCTGA

Upstream 100 bases:

>100_bases
ATGAAGCTCGTCCCACGCCGAATTTGGCGCAAAATGCCACGCTAAAACGGGGTAAAGTAGAGAAACTATGAGTATGGAAG
CAACCGCGCGCGTTTCTGAA

Downstream 100 bases:

>100_bases
GTAGAAAGCAACAAGGTTTAATTCATTATGACAGTTTACTTCATTGGTGCAGGCCCCGGCGCTGCAGATCTTCTTACACT
TCGTGCGCATAACATCATCA

Product: putative precorrin-6Y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MGRSKNDDGQAHTGSITVVGIGAGGVEELGAQARTALRQATIIIGSKRQLGLLPEDFQGDRIAWPSPLVPAIPALFAEFI
DKEVVVLGSGDPMFHGIGSTLHRLLPNHSMTVIPQPSSASLACARLGWALDTTSVYSLVTHPIAHLTLAIEQGDRFLVLG
RNHESPHEICEHLISLGQSTAEVTVLSDIGSVSETITSGAATDYPSNDSALNVIAIRPLAATRSRVPGLPDSEYVTDGQL
TKQHVRALAISALAPKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAF
DDVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQMLWALRKQFGGTISSFAISHEHTVGSFITMKPAL
PVHQWTVVKALTKEL

Sequences:

>Translated_415_residues
MGRSKNDDGQAHTGSITVVGIGAGGVEELGAQARTALRQATIIIGSKRQLGLLPEDFQGDRIAWPSPLVPAIPALFAEFI
DKEVVVLGSGDPMFHGIGSTLHRLLPNHSMTVIPQPSSASLACARLGWALDTTSVYSLVTHPIAHLTLAIEQGDRFLVLG
RNHESPHEICEHLISLGQSTAEVTVLSDIGSVSETITSGAATDYPSNDSALNVIAIRPLAATRSRVPGLPDSEYVTDGQL
TKQHVRALAISALAPKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAF
DDVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQMLWALRKQFGGTISSFAISHEHTVGSFITMKPAL
PVHQWTVVKALTKEL
>Mature_414_residues
GRSKNDDGQAHTGSITVVGIGAGGVEELGAQARTALRQATIIIGSKRQLGLLPEDFQGDRIAWPSPLVPAIPALFAEFID
KEVVVLGSGDPMFHGIGSTLHRLLPNHSMTVIPQPSSASLACARLGWALDTTSVYSLVTHPIAHLTLAIEQGDRFLVLGR
NHESPHEICEHLISLGQSTAEVTVLSDIGSVSETITSGAATDYPSNDSALNVIAIRPLAATRSRVPGLPDSEYVTDGQLT
KQHVRALAISALAPKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAFD
DVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVESEQMLWALRKQFGGTISSFAISHEHTVGSFITMKPALP
VHQWTVVKALTKEL

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 44124; Mature: 43993

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRSKNDDGQAHTGSITVVGIGAGGVEELGAQARTALRQATIIIGSKRQLGLLPEDFQGD
CCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCC
RIAWPSPLVPAIPALFAEFIDKEVVVLGSGDPMFHGIGSTLHRLLPNHSMTVIPQPSSAS
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
LACARLGWALDTTSVYSLVTHPIAHLTLAIEQGDRFLVLGRNHESPHEICEHLISLGQST
HHHHHHCCCCCHHHHHHHHHCCHHHEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCC
AEVTVLSDIGSVSETITSGAATDYPSNDSALNVIAIRPLAATRSRVPGLPDSEYVTDGQL
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCEECCCHH
TKQHVRALAISALAPKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRERILSN
HHHHHHHHHHHHCCCCCCHHHEECCCCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHH
AINLGVSDRIAVQQGAPRAFDDVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAV
HHCCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEE
TVESEQMLWALRKQFGGTISSFAISHEHTVGSFITMKPALPVHQWTVVKALTKEL
EECHHHHHHHHHHHHCCCHHHHEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GRSKNDDGQAHTGSITVVGIGAGGVEELGAQARTALRQATIIIGSKRQLGLLPEDFQGD
CCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCC
RIAWPSPLVPAIPALFAEFIDKEVVVLGSGDPMFHGIGSTLHRLLPNHSMTVIPQPSSAS
CCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
LACARLGWALDTTSVYSLVTHPIAHLTLAIEQGDRFLVLGRNHESPHEICEHLISLGQST
HHHHHHCCCCCHHHHHHHHHCCHHHEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCC
AEVTVLSDIGSVSETITSGAATDYPSNDSALNVIAIRPLAATRSRVPGLPDSEYVTDGQL
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCEECCCHH
TKQHVRALAISALAPKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRERILSN
HHHHHHHHHHHHCCCCCCHHHEECCCCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHH
AINLGVSDRIAVQQGAPRAFDDVPDNPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAV
HHCCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEE
TVESEQMLWALRKQFGGTISSFAISHEHTVGSFITMKPALPVHQWTVVKALTKEL
EECHHHHHHHHHHHHCCCHHHHEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]