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The map label for this gene is cobM [H]

Identifier: 38233823

GI number: 38233823

Start: 1236784

End: 1237557

Strand: Reverse

Name: cobM [H]

Synonym: DIP1235

Alternate gene names: 38233823

Gene position: 1237557-1236784 (Counterclockwise)

Preceding gene: 38233824

Following gene: 38233822

Centisome position: 49.73

GC content: 51.68

Gene sequence:

>774_bases
ATGACAGTTTACTTCATTGGTGCAGGCCCCGGCGCTGCAGATCTTCTTACACTTCGTGCGCATAACATCATCAAATCGGC
ACAGGTGTGCATGTACGCTGGATCAATTGTCCCACCAGAAGTGTTGGAATCGGTTCCACAAAACGCTGAGGTGATTAATA
CAGCCCGTATGCCGCTTGACCAGATCATGGAAAAAATTGTTGCTGCGCATAAGAATGGGCATGATGTTGCTCGGCTGCAG
TCTGGTGACCCCTCAATTTATTCGGCAGTGGCAGAGCAAGCTCGCAGGCTCACTGCGTTGGGGATTGACTATCAAATTGT
CCCAGGAGTACCCGCTTTTGCTGCTGTTGCCGCAGCATTAGGGCATGAGCTTACCGTCCCTACTGTCGGTCAAACAGTCA
TCCTCACTCGAGTTTCGGGTCGTGCGTCAGCTATGCCACAAGGTGAGGACCTGCCTACTTTAGGTAAGAGCGGCGCAACT
TTGTGTATCCATCTCGCAGCGCATGACATTGACCGTGTCGTATCAGAGCTGCTTCCTCAGTATGGTGAGTATTGTCCAGC
GGCTGTGGTTGCTTACGCCTCTCGTCCAGAGGAGGCAATTGTCCGGGGAACACTTGCTGACATTGCAGAAAAGACGCGAA
GTGCTGAGATTACCCGTACAGCAATTATTGTGGTCGGAAAAGTGCTCGGAGCTGAAGGTTTCCCCGATTCATTCCTATAC
TCCAATGACCGACCTCGAGATGAGCATGGTAGGACGATTCCATGCGCGCACTAA

Upstream 100 bases:

>100_bases
ATTCATCACCATGAAACCTGCATTACCGGTACACCAATGGACCGTAGTAAAAGCATTGACAAAGGAACTCTGAGTAGAAA
GCAACAAGGTTTAATTCATT

Downstream 100 bases:

>100_bases
TCTTGGGAGGTACTGGGGAAGGTCGCGACGTAGCTGCAATTCTTCACGTTGCAGGTTGGCGCGTGACAAGTTCCTTAGCC
GGGCGTGTTTCCAATCCGAA

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTVYFIGAGPGAADLLTLRAHNIIKSAQVCMYAGSIVPPEVLESVPQNAEVINTARMPLDQIMEKIVAAHKNGHDVARLQ
SGDPSIYSAVAEQARRLTALGIDYQIVPGVPAFAAVAAALGHELTVPTVGQTVILTRVSGRASAMPQGEDLPTLGKSGAT
LCIHLAAHDIDRVVSELLPQYGEYCPAAVVAYASRPEEAIVRGTLADIAEKTRSAEITRTAIIVVGKVLGAEGFPDSFLY
SNDRPRDEHGRTIPCAH

Sequences:

>Translated_257_residues
MTVYFIGAGPGAADLLTLRAHNIIKSAQVCMYAGSIVPPEVLESVPQNAEVINTARMPLDQIMEKIVAAHKNGHDVARLQ
SGDPSIYSAVAEQARRLTALGIDYQIVPGVPAFAAVAAALGHELTVPTVGQTVILTRVSGRASAMPQGEDLPTLGKSGAT
LCIHLAAHDIDRVVSELLPQYGEYCPAAVVAYASRPEEAIVRGTLADIAEKTRSAEITRTAIIVVGKVLGAEGFPDSFLY
SNDRPRDEHGRTIPCAH
>Mature_256_residues
TVYFIGAGPGAADLLTLRAHNIIKSAQVCMYAGSIVPPEVLESVPQNAEVINTARMPLDQIMEKIVAAHKNGHDVARLQS
GDPSIYSAVAEQARRLTALGIDYQIVPGVPAFAAVAAALGHELTVPTVGQTVILTRVSGRASAMPQGEDLPTLGKSGATL
CIHLAAHDIDRVVSELLPQYGEYCPAAVVAYASRPEEAIVRGTLADIAEKTRSAEITRTAIIVVGKVLGAEGFPDSFLYS
NDRPRDEHGRTIPCAH

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=245, Percent_Identity=26.530612244898, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322922, Length=236, Percent_Identity=25.4237288135593, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 27181; Mature: 27050

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYFIGAGPGAADLLTLRAHNIIKSAQVCMYAGSIVPPEVLESVPQNAEVINTARMPLD
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCHH
QIMEKIVAAHKNGHDVARLQSGDPSIYSAVAEQARRLTALGIDYQIVPGVPAFAAVAAAL
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
GHELTVPTVGQTVILTRVSGRASAMPQGEDLPTLGKSGATLCIHLAAHDIDRVVSELLPQ
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
YGEYCPAAVVAYASRPEEAIVRGTLADIAEKTRSAEITRTAIIVVGKVLGAEGFPDSFLY
HHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
SNDRPRDEHGRTIPCAH
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVYFIGAGPGAADLLTLRAHNIIKSAQVCMYAGSIVPPEVLESVPQNAEVINTARMPLD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCHH
QIMEKIVAAHKNGHDVARLQSGDPSIYSAVAEQARRLTALGIDYQIVPGVPAFAAVAAAL
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHH
GHELTVPTVGQTVILTRVSGRASAMPQGEDLPTLGKSGATLCIHLAAHDIDRVVSELLPQ
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
YGEYCPAAVVAYASRPEEAIVRGTLADIAEKTRSAEITRTAIIVVGKVLGAEGFPDSFLY
HHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
SNDRPRDEHGRTIPCAH
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]