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The map label for this gene is nupC [C]

Identifier: 15675687

GI number: 15675687

Start: 1549807

End: 1551009

Strand: Reverse

Name: nupC [C]

Synonym: SPy_1868

Alternate gene names: 15675687

Gene position: 1551009-1549807 (Counterclockwise)

Preceding gene: 15675688

Following gene: 15675686

Centisome position: 83.73

GC content: 35.99

Gene sequence:

>1203_bases
ATGCAATTTATTTATAGTATTATTGGTATTTTATTGGTATTAGGAATTGTGTATGCAATTTCTTTCAATCGTAAGAGTGT
TTCTCTAAGTTTAATTGGAAAAGCTCTTATCGTTCAATTCATTATTGCGCTAATCTTAGTACGTATCCCACTAGGCCAAC
AAATTGTTAGTGTTGTTTCAACTGGAGTTACTAGCGTAATCAACTGTGGTCAAGCTGGTTTAAATTTTGTGTTTGGGTCA
TTAGCAGATAGTGGCGCAAAAACTGGTTTTATTTTCGCTATTCAAACGCTTGGTAATATTGTTTTCTTATCTGCCCTAGT
TAGTCTACTTTATTATGTAGGAATCCTTGGATTTGTAGTAAAATGGATAGGTAAGGGCGTTGGTAAAATTATGAAATCCT
CAGAGGTTGAGAGTTTTGTTGCTGTAGCTAATATGTTTCTTGGTCAAACAGACAGTCCAATCTTGGTTAGCAAATACCTA
GGTCGTATGACTGATAGTGAGATAATGGTTGTGTTGGTATCAGGTATGGGAAGTATGTCAGTTTCTATTCTTGGTGGCTA
TATTGCATTAGGCATTCCAATGGAATATCTCTTGATTGCTTCAACAATGGTTCCTATTGGCAGTATTCTCATTGCTAAAA
TCTTATTGCCTCAAACAGAACCTGTTCAAAAAATTGATGACATTAAGATGGATAATAAAGGTAATAACGCCAATGTGATT
GATGCAATCGCTGAGGGTGCAAGCACAGGTGCACAAATGGCTTTCTCAATTGGTGCTAGTTTGATTGCCTTTGTTGGTTT
AGTTTCTTTGATTAATATGATGTTAAGTGGATTGGGAATCCGCTTAGAACAAATCTTTTCATATGTTTTTGCTCCATTTG
GTTTTCTTATGGGATTTGACCACAAAAACATTCTTCTAGAAGGAAACCTTCTTGGAAGTAAGTTGATTTTAAATGAGTTT
GTTTCGTTCCAACAATTGGGTCACCTAATCAAATCTTTAGATTATCGTACAGCATTGGTAGCAACTATTTCACTCTGTGG
TTTTGCTAATTTATCAAGTTTAGGTATTTGTGTTTCAGGTATTGCTGTTCTTTGCCCGGAGAAACGTAGCACCCTAGCTC
GACTTGTTTTCCGTGCAATGATTGGTGGTATTGCTGTAAGTATGCTTAGCGCCTTTATCGTCGGTATTGTAACTCTATTC
TAA

Upstream 100 bases:

>100_bases
TGGCTCATGATACAGAAGCAGCTATTCAAGTTGCTGTTGAAGCACTCCGCACACTTATTGAAAATGATAAATCACAATAA
GCGAGGTTTTGGAAGTCATC

Downstream 100 bases:

>100_bases
ACGTTGACAAAAGAAAGAAGGATAGTAACGTGGAAGTAAAAGATATTTTAAAAACGGTAGACCATACTTTGCTAGCAACA
ACAGCAACGTGGCCAGAAAT

Product: putative nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGS
LADSGAKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVI
DAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEF
VSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAFIVGIVTLF

Sequences:

>Translated_400_residues
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGS
LADSGAKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVI
DAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEF
VSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
>Mature_400_residues
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGS
LADSGAKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVI
DAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEF
VSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAFIVGIVTLF

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=364, Percent_Identity=35.4395604395604, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI227116277, Length=413, Percent_Identity=31.7191283292978, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI42542381, Length=416, Percent_Identity=31.25, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI1788485, Length=411, Percent_Identity=35.5231143552311, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1788488, Length=412, Percent_Identity=36.1650485436893, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788737, Length=384, Percent_Identity=26.3020833333333, Blast_Score=145, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17560276, Length=393, Percent_Identity=30.2798982188295, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71991794, Length=397, Percent_Identity=28.9672544080605, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25146537, Length=187, Percent_Identity=30.4812834224599, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45552517, Length=389, Percent_Identity=31.6195372750643, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19921868, Length=389, Percent_Identity=31.6195372750643, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI45552519, Length=389, Percent_Identity=31.6195372750643, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI281360430, Length=407, Percent_Identity=30.4668304668305, Blast_Score=178, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 42394; Mature: 42394

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQIVSVVS
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVV
HHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYLGRMTDSEIMVVLVSGMGSMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHEEHEECCCCCHH
VSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHH
DAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
HKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSG
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IAVLCPEKRSTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQIVSVVS
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVV
HHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYLGRMTDSEIMVVLVSGMGSMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHEEHEECCCCCHH
VSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHH
DAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
HKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSG
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IAVLCPEKRSTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]