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The map label for this gene is oxaA1

Identifier: 15674429

GI number: 15674429

Start: 214512

End: 215339

Strand: Direct

Name: oxaA1

Synonym: SPy_0247

Alternate gene names: 15674429

Gene position: 214512-215339 (Clockwise)

Preceding gene: 15674428

Following gene: 15674430

Centisome position: 11.58

GC content: 40.22

Gene sequence:

>828_bases
TTGAGAAAGGTTTTGAGAGTGAAGAAAAACATTAAAATTGCAAGAATAGTCCCCTTAGTTCTATTATTAGTGGCCTGTGG
TCGTGGTGAGGTAACGGCACAATCATCTAGTGGTTGGGACCAGTTGGTTTACTTATTTGCCAGAGCAATTCAATGGCTTT
CCTTTGATGGTTCAATTGGTGTTGGCATTATTCTTTTTACCCTTACTATCCGTCTCATGCTCATGCCTTTGTTTAACATG
CAAATCAAATCAAGCCAGAAGATGCAAGACATCCAACCTGAGCTTAGAGAATTGCAAAGGAAATACGCTGGTAAAGACAC
ACAAACGCGGATGAAGTTGGCTGAAGAAAGTCAAGCCCTTTACAAAAAATATGGGGTTAACCCTTATGCTAGTCTCTTAC
CCCTCTTAATTCAGATGCCAGTTATGATTGCCTTATTCCAAGCCTTGACACGGGTATCTTTCTTAAAAACAGGGACTTTC
TTGTGGGTGGAATTGGCACAACATGATCATTTGTACCTTTTACCAGTTTTGGCAGCTGTCTTCACTTTCTTGTCCACTTG
GTTGACCAATCTAGCGGCTAAAGAAAAAAATGTCATGATGACTGTTATGATTTATGTGATGCCGCTAATGATCTTTTTCA
TGGGCTTTAACTTGGCTAGTGGAGTAGTGCTCTATTGGACGGTCTCCAATGCCTTTCAAGTGGTACAACTACTGTTATTA
AACAATCCTTTTAAGATTATTGCGGAAAGACAACGTCTTGCCAATGAAGAAAAAGAACGCCGTCTTCGTGAACGTCGTGC
TCGTAAAAAAGCAATGAAGAGAAAATAG

Upstream 100 bases:

>100_bases
TCAGAGGATTTCGTGGTGATTGCCCGTAAGGGTGTCCACTCTTTGGAGTATCAAGAGCTTCAACAAAATTTACATCATGT
TTTAAAGTTAGCACAATTGC

Downstream 100 bases:

>100_bases
GAGTTTAGGTTATGGTATTATTTACAGGAAAAACAGTCGAAGAAGCTATCGAAACAGGACTTCAAGAGTTAGGGTTATCA
CGCCTTAAAGCGCATATCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNM
QIKSSQKMQDIQPELRELQRKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLL
NNPFKIIAERQRLANEEKERRLRERRARKKAMKRK

Sequences:

>Translated_275_residues
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNM
QIKSSQKMQDIQPELRELQRKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLL
NNPFKIIAERQRLANEEKERRLRERRARKKAMKRK
>Mature_275_residues
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNM
QIKSSQKMQDIQPELRELQRKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLL
NNPFKIIAERQRLANEEKERRLRERRARKKAMKRK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=229, Percent_Identity=31.8777292576419, Blast_Score=95, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321002, Length=194, Percent_Identity=27.319587628866, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24662345, Length=201, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356443, Length=201, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA1_STRP1 (P65631)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268603.1
- RefSeq:   YP_281572.1
- EnsemblBacteria:   EBSTRT00000000729
- EnsemblBacteria:   EBSTRT00000027703
- GeneID:   3572714
- GeneID:   900549
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0247
- KEGG:   spz:M5005_Spy_0208
- GeneTree:   EBGT00050000027293
- HOGENOM:   HBG560622
- OMA:   LMIFQTR
- ProtClustDB:   CLSK698264
- BioCyc:   SPYO160490:SPY0247-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0208-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 31764; Mature: 31764

Theoretical pI: Translated: 11.00; Mature: 11.00

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xafb63b0)-; HASH(0xc75c024)-; HASH(0xb1ef7b0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIG
CCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCH
VGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQRKYAGKDTQTRMKLAEESQAL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTFLWVELAQHDHLYLLPVLAAV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHH
FTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHH
NNPFKIIAERQRLANEEKERRLRERRARKKAMKRK
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIG
CCHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCH
VGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQRKYAGKDTQTRMKLAEESQAL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTFLWVELAQHDHLYLLPVLAAV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHH
FTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHH
NNPFKIIAERQRLANEEKERRLRERRARKKAMKRK
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296