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The map label for this gene is rnpA

Identifier: 15674428

GI number: 15674428

Start: 214187

End: 214546

Strand: Direct

Name: rnpA

Synonym: SPy_0246

Alternate gene names: 15674428

Gene position: 214187-214546 (Clockwise)

Preceding gene: 15674427

Following gene: 15674429

Centisome position: 11.56

GC content: 38.06

Gene sequence:

>360_bases
TTGAAGAAGACCTATCGTGTCAAGCGTGAGAAAGATTTCCAAGCCATATTTAAGGATGGAAAAAGTACAGCAAATCGAAA
ATTTGTCATTTATCATTTAAATAGAGGCCAAGACCACTTCCGTGTGGGTATTTCTGTCGGTAAAAAAATAGGAAATGCAG
TCACCAGAAATGCAGTCAAACGAAAGATACGTCATGTTATCATGGCATTAGGGCATCAGCTGAAGTCAGAGGATTTCGTG
GTGATTGCCCGTAAGGGTGTCCACTCTTTGGAGTATCAAGAGCTTCAACAAAATTTACATCATGTTTTAAAGTTAGCACA
ATTGCTTGAGAAAGGTTTTGAGAGTGAAGAAAAACATTAA

Upstream 100 bases:

>100_bases
GAAATAGTACAGAAAGAGGCTTAATCTGAAAGGGTCAGGGCTTTTTAATTTTTTAGGGGATGTGGTATAATGGTAATAAT
TTAGATATTGGAGTTAAATT

Downstream 100 bases:

>100_bases
AATTGCAAGAATAGTCCCCTTAGTTCTATTATTAGTGGCCTGTGGTCGTGGTGAGGTAACGGCACAATCATCTAGTGGTT
GGGACCAGTTGGTTTACTTA

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFV
VIARKGVHSLEYQELQQNLHHVLKLAQLLEKGFESEEKH

Sequences:

>Translated_119_residues
MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFV
VIARKGVHSLEYQELQQNLHHVLKLAQLLEKGFESEEKH
>Mature_119_residues
MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFV
VIARKGVHSLEYQELQQNLHHVLKLAQLLEKGFESEEKH

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_STRP1 (Q9A1J4)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268602.1
- RefSeq:   YP_281571.1
- ProteinModelPortal:   Q9A1J4
- SMR:   Q9A1J4
- EnsemblBacteria:   EBSTRT00000001693
- EnsemblBacteria:   EBSTRT00000029196
- GeneID:   3572713
- GeneID:   900548
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0246
- KEGG:   spz:M5005_Spy_0207
- GeneTree:   EBGT00050000028164
- HOGENOM:   HBG728160
- OMA:   KIGNAVM
- ProtClustDB:   PRK00499
- BioCyc:   SPYO160490:SPY0246-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0207-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13874; Mature: 13874

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVK
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RKIRHVIMALGHQLKSEDFVVIARKGVHSLEYQELQQNLHHVLKLAQLLEKGFESEEKH
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVK
CCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RKIRHVIMALGHQLKSEDFVVIARKGVHSLEYQELQQNLHHVLKLAQLLEKGFESEEKH
HHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296