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The map label for this gene is exoB [H]

Identifier: 13474741

GI number: 13474741

Start: 4583943

End: 4584944

Strand: Direct

Name: exoB [H]

Synonym: mlr5697

Alternate gene names: 13474741

Gene position: 4583943-4584944 (Clockwise)

Preceding gene: 13474739

Following gene: 13474742

Centisome position: 65.15

GC content: 65.37

Gene sequence:

>1002_bases
ATGCGGATGACGGTTTTGGTGACAGGCGGCGCCGGCTATATCGGCAGCCACATGGTCTGGGAATTGCTGGATGCGGGTGA
GAGAGTGGTCGTGCTCGACCGCCTTTCCACCGGCTTCGAATGGGCGGTGGCGCCGGAGGCAAAGCTGGTCGTTGGCGATG
TCGCCGACAAGGAATTGGTCGGTTCGATCATCAGGGACAATCATGTCGACGCGATCATCCATTTCGCCGGTTCCATCGTG
GTCCCCGAATCGGTCGCCGACCCGCTCGCCTACTACGAGAACAACACCTCAAAGACCCGCACGTTGATCGAAACCGCGGT
GCGCGAGGGTGTGCCGCATTTCATCTTTTCCTCGACCGCCGCCGTCTATGGCGGCGCTGGGCTGGAGCCGGTGCGCGAGG
ATGCCCGCCTGGCGCCGGAATCGCCCTATGGCCTGTCCAAGCTGATGAGCGAGTGGATGTTGCGCGATGCCGGCCTCGCG
CACGACATCCGCTACACGGCGCTGCGCTATTTCAACGTCGCCGGCGCCGACCCGAAGGGCCGCACCGGCCAGTCGACGCC
GGGCGCCACCCATCTCATCAAGGTCGCCTGCGAGACCGCGCTCGGCAAGCGTCCCTTCATGCAGGTGTTCGGTACCGACT
ATCCGACGCCGGACGGCACCTGCATGCGCGACTACATCCATGTCAGCGACCTGGCAGCCGCGCATCGCCTGGCGCTGCAG
CGGCTGCGCGCCGGGGGTACGAGCCTCGTCGCCAATTGCGGCTATAGCCATGGCTATTCGGTGCTTGAGGTGATCGACAG
CGTTCGGCGCGCTTTTGGCCGCGATTTCGAGGTGAAGATGGGCGACCGGCGTCCCGGCGATGCGGCAGCGGTGGTCGCCA
ATTCGGACCTTGCCCGGGCGGAACTCGGTTGGACGCCGCAGCGCGACGATCTCGACCAGATCGTTGCCGACGCACTCGCC
TGGGAACGCATCCTGACCAGCAAGAACTCCGCCCGCGGCTGA

Upstream 100 bases:

>100_bases
TTTGGTGAACGCCGGTTACCAAGGGTTCTAATGGCCATGCGGCAGGCTTTCCAGTAAGGCGGTGTTTGAGACAGTTTCCG
ATAAATCTTGAGATGCGAGG

Downstream 100 bases:

>100_bases
GCCAAGCCCCGAGGGCTCGCAAGGCACGCGCCGACGCGCTATGGAAGGCATTCGCGGCAGGGCGCTGCGCCGCGAAGAGC
TTTTGGGGGATGGCATGAAG

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRMTVLVTGGAGYIGSHMVWELLDAGERVVVLDRLSTGFEWAVAPEAKLVVGDVADKELVGSIIRDNHVDAIIHFAGSIV
VPESVADPLAYYENNTSKTRTLIETAVREGVPHFIFSSTAAVYGGAGLEPVREDARLAPESPYGLSKLMSEWMLRDAGLA
HDIRYTALRYFNVAGADPKGRTGQSTPGATHLIKVACETALGKRPFMQVFGTDYPTPDGTCMRDYIHVSDLAAAHRLALQ
RLRAGGTSLVANCGYSHGYSVLEVIDSVRRAFGRDFEVKMGDRRPGDAAAVVANSDLARAELGWTPQRDDLDQIVADALA
WERILTSKNSARG

Sequences:

>Translated_333_residues
MRMTVLVTGGAGYIGSHMVWELLDAGERVVVLDRLSTGFEWAVAPEAKLVVGDVADKELVGSIIRDNHVDAIIHFAGSIV
VPESVADPLAYYENNTSKTRTLIETAVREGVPHFIFSSTAAVYGGAGLEPVREDARLAPESPYGLSKLMSEWMLRDAGLA
HDIRYTALRYFNVAGADPKGRTGQSTPGATHLIKVACETALGKRPFMQVFGTDYPTPDGTCMRDYIHVSDLAAAHRLALQ
RLRAGGTSLVANCGYSHGYSVLEVIDSVRRAFGRDFEVKMGDRRPGDAAAVVANSDLARAELGWTPQRDDLDQIVADALA
WERILTSKNSARG
>Mature_333_residues
MRMTVLVTGGAGYIGSHMVWELLDAGERVVVLDRLSTGFEWAVAPEAKLVVGDVADKELVGSIIRDNHVDAIIHFAGSIV
VPESVADPLAYYENNTSKTRTLIETAVREGVPHFIFSSTAAVYGGAGLEPVREDARLAPESPYGLSKLMSEWMLRDAGLA
HDIRYTALRYFNVAGADPKGRTGQSTPGATHLIKVACETALGKRPFMQVFGTDYPTPDGTCMRDYIHVSDLAAAHRLALQ
RLRAGGTSLVANCGYSHGYSVLEVIDSVRRAFGRDFEVKMGDRRPGDAAAVVANSDLARAELGWTPQRDDLDQIVADALA
WERILTSKNSARG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=39.7058823529412, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=39.7058823529412, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=39.7058823529412, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=24.7619047619048, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI310132178, Length=256, Percent_Identity=29.296875, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI310113012, Length=256, Percent_Identity=29.296875, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI239745448, Length=256, Percent_Identity=29.296875, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7657641, Length=268, Percent_Identity=24.6268656716418, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=40.1812688821752, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI48994969, Length=363, Percent_Identity=25.8953168044077, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790049, Length=271, Percent_Identity=27.6752767527675, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=339, Percent_Identity=37.1681415929204, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71982038, Length=341, Percent_Identity=36.950146627566, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17568069, Length=252, Percent_Identity=29.3650793650794, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=317, Percent_Identity=24.6056782334385, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=340, Percent_Identity=23.5294117647059, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=321, Percent_Identity=38.6292834890966, Blast_Score=192, Evalue=8e-50,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=39.0532544378698, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=22.7848101265823, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36046; Mature: 36046

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTVLVTGGAGYIGSHMVWELLDAGERVVVLDRLSTGFEWAVAPEAKLVVGDVADKELV
CEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCEEEEECCCCHHHH
GSIIRDNHVDAIIHFAGSIVVPESVADPLAYYENNTSKTRTLIETAVREGVPHFIFSSTA
HHHHHCCCHHHHHHHHCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCHH
AVYGGAGLEPVREDARLAPESPYGLSKLMSEWMLRDAGLAHDIRYTALRYFNVAGADPKG
HHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCC
RTGQSTPGATHLIKVACETALGKRPFMQVFGTDYPTPDGTCMRDYIHVSDLAAAHRLALQ
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RLRAGGTSLVANCGYSHGYSVLEVIDSVRRAFGRDFEVKMGDRRPGDAAAVVANSDLARA
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCHHHH
ELGWTPQRDDLDQIVADALAWERILTSKNSARG
HCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRMTVLVTGGAGYIGSHMVWELLDAGERVVVLDRLSTGFEWAVAPEAKLVVGDVADKELV
CEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCEEEEECCCCHHHH
GSIIRDNHVDAIIHFAGSIVVPESVADPLAYYENNTSKTRTLIETAVREGVPHFIFSSTA
HHHHHCCCHHHHHHHHCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCHH
AVYGGAGLEPVREDARLAPESPYGLSKLMSEWMLRDAGLAHDIRYTALRYFNVAGADPKG
HHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCC
RTGQSTPGATHLIKVACETALGKRPFMQVFGTDYPTPDGTCMRDYIHVSDLAAAHRLALQ
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RLRAGGTSLVANCGYSHGYSVLEVIDSVRRAFGRDFEVKMGDRRPGDAAAVVANSDLARA
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCHHHH
ELGWTPQRDDLDQIVADALAWERILTSKNSARG
HCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]