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The map label for this gene is aspC [H]

Identifier: 13474739

GI number: 13474739

Start: 4580977

End: 4582143

Strand: Direct

Name: aspC [H]

Synonym: mlr5693

Alternate gene names: 13474739

Gene position: 4580977-4582143 (Clockwise)

Preceding gene: 13474738

Following gene: 13474741

Centisome position: 65.11

GC content: 65.38

Gene sequence:

>1167_bases
ATGAGCCTGATCGATAGCTTTCGCGCCGAAGCCCGTGCCGCACCGGAAAGCGGCATTGTCGCCGTCGTCAACTACGGCCG
CCTGCGCGAGGGCCTGATCCCGCTCTGGGCCGGCGAGGGCGACCTGCCGACACCCGCCTTCATCACCGATGCCGCGTCGA
AGGCGCTGGCCGGCGGCGAGACGTTCTACACCTGGCAGAGGGGCATCCCCGACCTCAGGCAGGCGCTGGCACGCTACTAC
GCCAGGCACTTTGGTAAGACCTTCCCGGAGGAACAATTCATCGTCACCGGATCCGGCATGCATGCCATCCAGATGTCGCT
TACCGCGCTGGCCGGCGCCGGCGACGAGGTGATCTATCTGTCGCCGGCCTGGCCGAATTTCGACGCCGCCGCCGCCCTCT
CAGGAGCCGTTCCGGTGCCGGTCACGCTCGATCATTCCGGCAATGGCTGGTCCTGCGACGTCGAGAAGATCGCCGCGGCG
ATCACGCCGCGCACCAGGGCACTGTTCATCAACACGCCGTCGAACCCGACCGGCTGGACCGCCGATCACGAGACCTTGCA
AGCGATCCTCGACCTCGCGCGGGCCAAAAACGTCTGGATCATCGCCGACGAGATCTATTCGCTGTTCCACTATGGCCATG
GCCGCGCGCCGTCCTTCCTCGACATCGCGACGGAGGAAGACCGCATCCTGTTCGTCAACTCCTTTTCCAAGAACTGGGCG
ATGACCGGCTGGCGCGTCGGCTGGATCAAGACGCATCCGAGCCTGCAGCAGGTGTTCGAGAACCTGATCCAATATTCGAA
TTCCGGCGTTGCCCAGTTCATGCAGCGCGGCGCGGTCGCGGCCCTTGACGAGGGCGATGGGTTCGTCGCCGAGCAGGTGG
AGCGGGCGAGAAAAGCGCGCGATCTGGTTTGCGGCATTCTCGGCGCCACTGGCCGCGCGCGCTTTACCGTGCCGCAGGGC
GCCTTCTATCTGTTCTTCACCGTCGACGGTATCACCGATTCCCGTACCGCCGCCTTCGACATCGTCGACAAGGCCAATGT
CGGCCTGGCGCCCGGCACCGCCTTCGGCCCCGGCGGCGAAGCCTTCCTGCGGCTGTGCTTCCACCGCCGCCTCGATCAGC
TCGAAGAAGCGGCGCACCGGCTGGCGAAATGGATGAAGAGCATTTGA

Upstream 100 bases:

>100_bases
GAAACGGTTTTCCGTCCGGAATTGCGTTAAAATAGAGAGTTAGAGCGGTTTGCCGTTTCCGTGAAACGGTGAACTGCTCT
AAGGGAAAACGGATTTGTCC

Downstream 100 bases:

>100_bases
GCCGCCGAAGCCCGATTTGAAAATCGCTCCGGCGAGTCAGCTGGCGTGGGTGTCGAGAACCGGAGCGCAGCGGACATTCA
AGTCCGTGAGCACGCGCATG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSLIDSFRAEARAAPESGIVAVVNYGRLREGLIPLWAGEGDLPTPAFITDAASKALAGGETFYTWQRGIPDLRQALARYY
ARHFGKTFPEEQFIVTGSGMHAIQMSLTALAGAGDEVIYLSPAWPNFDAAAALSGAVPVPVTLDHSGNGWSCDVEKIAAA
ITPRTRALFINTPSNPTGWTADHETLQAILDLARAKNVWIIADEIYSLFHYGHGRAPSFLDIATEEDRILFVNSFSKNWA
MTGWRVGWIKTHPSLQQVFENLIQYSNSGVAQFMQRGAVAALDEGDGFVAEQVERARKARDLVCGILGATGRARFTVPQG
AFYLFFTVDGITDSRTAAFDIVDKANVGLAPGTAFGPGGEAFLRLCFHRRLDQLEEAAHRLAKWMKSI

Sequences:

>Translated_388_residues
MSLIDSFRAEARAAPESGIVAVVNYGRLREGLIPLWAGEGDLPTPAFITDAASKALAGGETFYTWQRGIPDLRQALARYY
ARHFGKTFPEEQFIVTGSGMHAIQMSLTALAGAGDEVIYLSPAWPNFDAAAALSGAVPVPVTLDHSGNGWSCDVEKIAAA
ITPRTRALFINTPSNPTGWTADHETLQAILDLARAKNVWIIADEIYSLFHYGHGRAPSFLDIATEEDRILFVNSFSKNWA
MTGWRVGWIKTHPSLQQVFENLIQYSNSGVAQFMQRGAVAALDEGDGFVAEQVERARKARDLVCGILGATGRARFTVPQG
AFYLFFTVDGITDSRTAAFDIVDKANVGLAPGTAFGPGGEAFLRLCFHRRLDQLEEAAHRLAKWMKSI
>Mature_387_residues
SLIDSFRAEARAAPESGIVAVVNYGRLREGLIPLWAGEGDLPTPAFITDAASKALAGGETFYTWQRGIPDLRQALARYYA
RHFGKTFPEEQFIVTGSGMHAIQMSLTALAGAGDEVIYLSPAWPNFDAAAALSGAVPVPVTLDHSGNGWSCDVEKIAAAI
TPRTRALFINTPSNPTGWTADHETLQAILDLARAKNVWIIADEIYSLFHYGHGRAPSFLDIATEEDRILFVNSFSKNWAM
TGWRVGWIKTHPSLQQVFENLIQYSNSGVAQFMQRGAVAALDEGDGFVAEQVERARKARDLVCGILGATGRARFTVPQGA
FYLFFTVDGITDSRTAAFDIVDKANVGLAPGTAFGPGGEAFLRLCFHRRLDQLEEAAHRLAKWMKSI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=26.3427109974425, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=26.3427109974425, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=23.4096692111959, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=23.4096692111959, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4507369, Length=340, Percent_Identity=27.6470588235294, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI169881281, Length=332, Percent_Identity=24.6987951807229, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI7705897, Length=390, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI33469970, Length=390, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4885351, Length=236, Percent_Identity=27.9661016949153, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788722, Length=356, Percent_Identity=25.2808988764045, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1788627, Length=339, Percent_Identity=28.9085545722714, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786816, Length=354, Percent_Identity=24.8587570621469, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787909, Length=353, Percent_Identity=21.8130311614731, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787710, Length=186, Percent_Identity=27.9569892473118, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=323, Percent_Identity=26.3157894736842, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=239, Percent_Identity=28.4518828451883, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=391, Percent_Identity=23.0179028132992, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=391, Percent_Identity=23.0179028132992, Blast_Score=102, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=232, Percent_Identity=34.051724137931, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320317, Length=152, Percent_Identity=27.6315789473684, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=25.2577319587629, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=25.2577319587629, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=25.2577319587629, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=25.2577319587629, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=24.2105263157895, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42297; Mature: 42166

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDSFRAEARAAPESGIVAVVNYGRLREGLIPLWAGEGDLPTPAFITDAASKALAGGE
CCHHHHHHHHHCCCCCCCEEEEEECCHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCC
TFYTWQRGIPDLRQALARYYARHFGKTFPEEQFIVTGSGMHAIQMSLTALAGAGDEVIYL
EEEEHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEE
SPAWPNFDAAAALSGAVPVPVTLDHSGNGWSCDVEKIAAAITPRTRALFINTPSNPTGWT
CCCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCC
ADHETLQAILDLARAKNVWIIADEIYSLFHYGHGRAPSFLDIATEEDRILFVNSFSKNWA
CCHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCC
MTGWRVGWIKTHPSLQQVFENLIQYSNSGVAQFMQRGAVAALDEGDGFVAEQVERARKAR
CCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
DLVCGILGATGRARFTVPQGAFYLFFTVDGITDSRTAAFDIVDKANVGLAPGTAFGPGGE
HHHHHHHCCCCCEEEECCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCHH
AFLRLCFHRRLDQLEEAAHRLAKWMKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLIDSFRAEARAAPESGIVAVVNYGRLREGLIPLWAGEGDLPTPAFITDAASKALAGGE
CHHHHHHHHHCCCCCCCEEEEEECCHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCCCC
TFYTWQRGIPDLRQALARYYARHFGKTFPEEQFIVTGSGMHAIQMSLTALAGAGDEVIYL
EEEEHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEE
SPAWPNFDAAAALSGAVPVPVTLDHSGNGWSCDVEKIAAAITPRTRALFINTPSNPTGWT
CCCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCC
ADHETLQAILDLARAKNVWIIADEIYSLFHYGHGRAPSFLDIATEEDRILFVNSFSKNWA
CCHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCC
MTGWRVGWIKTHPSLQQVFENLIQYSNSGVAQFMQRGAVAALDEGDGFVAEQVERARKAR
CCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
DLVCGILGATGRARFTVPQGAFYLFFTVDGITDSRTAAFDIVDKANVGLAPGTAFGPGGE
HHHHHHHCCCCCEEEECCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCHH
AFLRLCFHRRLDQLEEAAHRLAKWMKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]