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The map label for this gene is dppB [H]

Identifier: 13474537

GI number: 13474537

Start: 4353026

End: 4354033

Strand: Reverse

Name: dppB [H]

Synonym: mll5440

Alternate gene names: 13474537

Gene position: 4354033-4353026 (Counterclockwise)

Preceding gene: 13474538

Following gene: 13474536

Centisome position: 61.88

GC content: 62.5

Gene sequence:

>1008_bases
ATGCTCCTGCAACGATTCCTGATCCGTCTCCTGACGATGCTGATCACGCTGTTCGGCGTGGCCGTCGTCGTTTTCGTCGT
GATCCGCGTCGCGCCCGGCGATCCGATCGCCATGATGCTGCCGCCCGGCGCGACGGATGACGACATCGCCCGCCTGCGCG
CACTCTACGGGCTCGACAAGACCATCGTGCAGCAATTCTTCATCTGGCTGTCCGGCGTGGTCCGGGGCGATTTCGGCACC
TCGATTTCGCTCAGGCAGGATGTGCTCGGCCTCGTCTTCAACCGGCTGCCGGCCACGCTGGAGCTAGCCATCGTCGCGCT
GATCATGGCAGTGACGCTCGGCGGTACGACGGCCATTCTCGGCGCGCGCGAACGCGGCACGGCGGTGGAAGCCGGCATCG
ACATCGCCAGCGGGGCGGCACTCTCCATTCCCGATTTCCTGTGGGGCCTGGTGCTGATCCTTTTGTTCGGCGTGCTGGTG
CCGATCTTCGACATTTCCGGCCGGGTGTCGCCGCAGCTCGACCTGCCCTTCGTCACCCAGTTCTATTTCTTCGAAAGCCT
GATGCGGCTGCGCTTCGACCTGACCTGGGATCTCCTCAAACACATGCTGATGCCGGCGGTGGCGCTGGCGCTGCCACTGG
CGGCGATCATATCGCAACTGTTGAAACAGTCGCTGAAGGAAGTGCTCGACCTCGACTATGTCGTGCTGGCGCGAGTGAAA
GGGTTTTCGGAGACGCAGGTCATCCTGCGCGAGGCGCTGAAGAATGCGTCTTTGCCGACGCTGACGCTGGTCGGCGTGCA
GTTCACCTTCCTGATTGGCGGCACCGTCATCGTCGAGCGGCTGTTTTCCTATGAAGGCCTCGGCAATATGGCGATCGATG
CCGTCATCAACCGCGACCTGCCGCTGATCCAGGGCATCGTGCTGGTGTTCGCGCTGCTGTTCGTGCTGATCAACCTTGCC
GTCGACATGATGTATGCGCTGCTCAATCCGAGGCTGCGCCATGGATAG

Upstream 100 bases:

>100_bases
CCCGGCCTGATATCGGCCTGAACTTGCCGCGCGCCGTCCATAGCGACGGCGCGCATTTTCTATCAGGCATACGAGCCAGC
AGGCTCCTGCAAAGATTTAC

Downstream 100 bases:

>100_bases
GGCCTCAAGACGCGGACTGAGCCCCAGGCTGTGGCTCGCCGGCGGCTGGCTGCTGCTGGCGCTGCTGGCGGCGATCTTCG
CGCCGCTGGTCGCGCCGCAG

Product: ABC transporter, permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLLQRFLIRLLTMLITLFGVAVVVFVVIRVAPGDPIAMMLPPGATDDDIARLRALYGLDKTIVQQFFIWLSGVVRGDFGT
SISLRQDVLGLVFNRLPATLELAIVALIMAVTLGGTTAILGARERGTAVEAGIDIASGAALSIPDFLWGLVLILLFGVLV
PIFDISGRVSPQLDLPFVTQFYFFESLMRLRFDLTWDLLKHMLMPAVALALPLAAIISQLLKQSLKEVLDLDYVVLARVK
GFSETQVILREALKNASLPTLTLVGVQFTFLIGGTVIVERLFSYEGLGNMAIDAVINRDLPLIQGIVLVFALLFVLINLA
VDMMYALLNPRLRHG

Sequences:

>Translated_335_residues
MLLQRFLIRLLTMLITLFGVAVVVFVVIRVAPGDPIAMMLPPGATDDDIARLRALYGLDKTIVQQFFIWLSGVVRGDFGT
SISLRQDVLGLVFNRLPATLELAIVALIMAVTLGGTTAILGARERGTAVEAGIDIASGAALSIPDFLWGLVLILLFGVLV
PIFDISGRVSPQLDLPFVTQFYFFESLMRLRFDLTWDLLKHMLMPAVALALPLAAIISQLLKQSLKEVLDLDYVVLARVK
GFSETQVILREALKNASLPTLTLVGVQFTFLIGGTVIVERLFSYEGLGNMAIDAVINRDLPLIQGIVLVFALLFVLINLA
VDMMYALLNPRLRHG
>Mature_335_residues
MLLQRFLIRLLTMLITLFGVAVVVFVVIRVAPGDPIAMMLPPGATDDDIARLRALYGLDKTIVQQFFIWLSGVVRGDFGT
SISLRQDVLGLVFNRLPATLELAIVALIMAVTLGGTTAILGARERGTAVEAGIDIASGAALSIPDFLWGLVLILLFGVLV
PIFDISGRVSPQLDLPFVTQFYFFESLMRLRFDLTWDLLKHMLMPAVALALPLAAIISQLLKQSLKEVLDLDYVVLARVK
GFSETQVILREALKNASLPTLTLVGVQFTFLIGGTVIVERLFSYEGLGNMAIDAVINRDLPLIQGIVLVFALLFVLINLA
VDMMYALLNPRLRHG

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=36.7647058823529, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1787053, Length=333, Percent_Identity=33.9339339339339, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=31.9402985074627, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=28.4023668639053, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787761, Length=328, Percent_Identity=31.7073170731707, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1788504, Length=372, Percent_Identity=27.1505376344086, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=26.7148014440433, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36689; Mature: 36689

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQRFLIRLLTMLITLFGVAVVVFVVIRVAPGDPIAMMLPPGATDDDIARLRALYGLDK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCH
TIVQQFFIWLSGVVRGDFGTSISLRQDVLGLVFNRLPATLELAIVALIMAVTLGGTTAIL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHH
GARERGTAVEAGIDIASGAALSIPDFLWGLVLILLFGVLVPIFDISGRVSPQLDLPFVTQ
CCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
FYFFESLMRLRFDLTWDLLKHMLMPAVALALPLAAIISQLLKQSLKEVLDLDYVVLARVK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GFSETQVILREALKNASLPTLTLVGVQFTFLIGGTVIVERLFSYEGLGNMAIDAVINRDL
CCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
PLIQGIVLVFALLFVLINLAVDMMYALLNPRLRHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MLLQRFLIRLLTMLITLFGVAVVVFVVIRVAPGDPIAMMLPPGATDDDIARLRALYGLDK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCH
TIVQQFFIWLSGVVRGDFGTSISLRQDVLGLVFNRLPATLELAIVALIMAVTLGGTTAIL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHH
GARERGTAVEAGIDIASGAALSIPDFLWGLVLILLFGVLVPIFDISGRVSPQLDLPFVTQ
CCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
FYFFESLMRLRFDLTWDLLKHMLMPAVALALPLAAIISQLLKQSLKEVLDLDYVVLARVK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GFSETQVILREALKNASLPTLTLVGVQFTFLIGGTVIVERLFSYEGLGNMAIDAVINRDL
CCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
PLIQGIVLVFALLFVLINLAVDMMYALLNPRLRHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]