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The map label for this gene is gsiD [H]

Identifier: 13474536

GI number: 13474536

Start: 4352191

End: 4353060

Strand: Reverse

Name: gsiD [H]

Synonym: mll5439

Alternate gene names: 13474536

Gene position: 4353060-4352191 (Counterclockwise)

Preceding gene: 13474537

Following gene: 13474535

Centisome position: 61.87

GC content: 66.44

Gene sequence:

>870_bases
ATGCGCTGCTCAATCCGAGGCTGCGCCATGGATAGGGCCTCAAGACGCGGACTGAGCCCCAGGCTGTGGCTCGCCGGCGG
CTGGCTGCTGCTGGCGCTGCTGGCGGCGATCTTCGCGCCGCTGGTCGCGCCGCAGGACCCGCTGGCGCAGGATCTGATGC
TGGAGCGGCTGCCGCCCTTCTGGCTCGATGGCGCCGAGCCCGGCTATTGGCTGGGCACCGACAGCCTCGGCCGCGATCTG
TTGTCCCGGCTGATCTTCGGCGGCCGTATCGCCTTCATCGTCGCATTCGCGGCGGCCATCGCCGCCTGCCTCGTCGGCTC
GACGCTCGGGCTGATCGCAGGCTATTTCGGCGGCTGGGCGGATCGCATCATCTCGCGCATCGTCGATATCTGGATGGCGT
TTCCGCCGGTGCTGTTCGCCATCCTGCTGGTGGCGGTGCTGGGCACGGGCCTCAGCTCCGTCATCCTGGCGATTGCCATC
ATCGACTGGACGCGCTTTTGCCGGGTGATCCGCGCCGAGGCGATGGGCCAGTCGCGCATGGATTATGTCGAAAATGCCCG
CATCGCCGGCTATGGCCGCATCGGCATCATGCTGCGTGAAGTGCTGCCCAATGTGGTGCCGTCGATCGTGGCGCTGCTGT
CCCTGGAGATGGGCATCGCCGTCATCGTCGAGGCGATCCTGTCCTTCGTCAACCTGTCGATCTCGACCGACGATCCGACC
TGGGGCGGCATCATCGCCGAGGGCCGGCTGTCCATCCACCAGGCATGGTGGGTGCTGGTGTTTCCGCTGATCACGCTGAT
CCTCACCGTGCTGTCGTTCAGCCAATTCGGCGAAGCGCTGAAGGCGCGTTTCGACCCGGTGCTGCGATGA

Upstream 100 bases:

>100_bases
ATCGATGCCGTCATCAACCGCGACCTGCCGCTGATCCAGGGCATCGTGCTGGTGTTCGCGCTGCTGTTCGTGCTGATCAA
CCTTGCCGTCGACATGATGT

Downstream 100 bases:

>100_bases
GCGCCTGTCTCGACATCGCCAATCTCAGCGCCGTGCTGCCGAACGGCCAGCGCGTGCTGCGCTCGGTGTCGCTTTCCGTG
CAGCCCGGCGAGGTGCGCGC

Product: ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MRCSIRGCAMDRASRRGLSPRLWLAGGWLLLALLAAIFAPLVAPQDPLAQDLMLERLPPFWLDGAEPGYWLGTDSLGRDL
LSRLIFGGRIAFIVAFAAAIAACLVGSTLGLIAGYFGGWADRIISRIVDIWMAFPPVLFAILLVAVLGTGLSSVILAIAI
IDWTRFCRVIRAEAMGQSRMDYVENARIAGYGRIGIMLREVLPNVVPSIVALLSLEMGIAVIVEAILSFVNLSISTDDPT
WGGIIAEGRLSIHQAWWVLVFPLITLILTVLSFSQFGEALKARFDPVLR

Sequences:

>Translated_289_residues
MRCSIRGCAMDRASRRGLSPRLWLAGGWLLLALLAAIFAPLVAPQDPLAQDLMLERLPPFWLDGAEPGYWLGTDSLGRDL
LSRLIFGGRIAFIVAFAAAIAACLVGSTLGLIAGYFGGWADRIISRIVDIWMAFPPVLFAILLVAVLGTGLSSVILAIAI
IDWTRFCRVIRAEAMGQSRMDYVENARIAGYGRIGIMLREVLPNVVPSIVALLSLEMGIAVIVEAILSFVNLSISTDDPT
WGGIIAEGRLSIHQAWWVLVFPLITLILTVLSFSQFGEALKARFDPVLR
>Mature_289_residues
MRCSIRGCAMDRASRRGLSPRLWLAGGWLLLALLAAIFAPLVAPQDPLAQDLMLERLPPFWLDGAEPGYWLGTDSLGRDL
LSRLIFGGRIAFIVAFAAAIAACLVGSTLGLIAGYFGGWADRIISRIVDIWMAFPPVLFAILLVAVLGTGLSSVILAIAI
IDWTRFCRVIRAEAMGQSRMDYVENARIAGYGRIGIMLREVLPNVVPSIVALLSLEMGIAVIVEAILSFVNLSISTDDPT
WGGIIAEGRLSIHQAWWVLVFPLITLILTVLSFSQFGEALKARFDPVLR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=263, Percent_Identity=36.8821292775665, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1787760, Length=258, Percent_Identity=34.1085271317829, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789964, Length=259, Percent_Identity=36.6795366795367, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=31.8367346938775, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=32.7402135231317, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787549, Length=245, Percent_Identity=30.6122448979592, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=26.605504587156, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31448; Mature: 31448

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00485 A_DEAMINASE ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCSIRGCAMDRASRRGLSPRLWLAGGWLLLALLAAIFAPLVAPQDPLAQDLMLERLPPF
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
WLDGAEPGYWLGTDSLGRDLLSRLIFGGRIAFIVAFAAAIAACLVGSTLGLIAGYFGGWA
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRIISRIVDIWMAFPPVLFAILLVAVLGTGLSSVILAIAIIDWTRFCRVIRAEAMGQSRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DYVENARIAGYGRIGIMLREVLPNVVPSIVALLSLEMGIAVIVEAILSFVNLSISTDDPT
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
WGGIIAEGRLSIHQAWWVLVFPLITLILTVLSFSQFGEALKARFDPVLR
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRCSIRGCAMDRASRRGLSPRLWLAGGWLLLALLAAIFAPLVAPQDPLAQDLMLERLPPF
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
WLDGAEPGYWLGTDSLGRDLLSRLIFGGRIAFIVAFAAAIAACLVGSTLGLIAGYFGGWA
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRIISRIVDIWMAFPPVLFAILLVAVLGTGLSSVILAIAIIDWTRFCRVIRAEAMGQSRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DYVENARIAGYGRIGIMLREVLPNVVPSIVALLSLEMGIAVIVEAILSFVNLSISTDDPT
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
WGGIIAEGRLSIHQAWWVLVFPLITLILTVLSFSQFGEALKARFDPVLR
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA