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The map label for this gene is hbpA [H]

Identifier: 13474538

GI number: 13474538

Start: 4354124

End: 4355653

Strand: Reverse

Name: hbpA [H]

Synonym: mll5441

Alternate gene names: 13474538

Gene position: 4355653-4354124 (Counterclockwise)

Preceding gene: 13474539

Following gene: 13474537

Centisome position: 61.9

GC content: 60.46

Gene sequence:

>1530_bases
ATGAAAATCAACAGACGCGAATTGCTGGGATACAGTGCCGCTGCACTCGGCGTGGCCGCCATTGGCTTGCCTAAAATCGC
CAAGGCCGCTGCCGGCGAACTGACCATCGCCTACAATGTAAACCTGCCGTCCTGGGATCCGACCACCGGACCCTCGGCTG
TCAACCCGACCATCCAGGGTCTCTACCAGTCGGTGTTCGACCAGATCATCTCGCAAAAGCCCGACCTGTCCTTCGCACCT
GGCCTGCTTACCGAATGGGGCTGGAACGACGACCGCACCAAGGTGACGATGACGGTGCGCGAGGGCGTGAAATGGCATGA
CGGCTCGCCGTTCACGCCCGAGGACGTTGTCTGGTCGCTGCAGCGCGCGGGCGACGAAAAAACCGGCAACCCGATCCAGT
TCGTATGGAAGAACGTCAACAACTTCAAGATCGACGGCAACAAGATCACGGGCGACGTGGTGCAGTTCGACCCGGTCTAT
TTCAAATGGATGTCGTTCCTGACCGGCTACATCCTGCCGAAGGCCTACTACGAGAAGGTCGGCGCTGAAGGTTTCGAGAA
GGCGCCGATCGGCACTGGCCCCTACATGGTGGAAAAGTTCGAGCGCAACGCCTTCCTGCGGCTGAAGGCCAATCCGAACT
ATTGGGGCGGCAAGCCGGCTTTCGAAAATGTGACGATCAAGTTCGTCACCGACGCGGCGAGCCGCGTCGCCGAGATCGAA
TCCGGCTCCTCGCAGGTGACGCTCGAAATCCCCTACGAGGAATATGACCGCCTGATCGCCAAGGACGGACTTGCCGGCTC
GATCAAGAATGTCTCCGACATCGGCATGATCTTCTTCAACAACAAGGATGCCATGCTCGACAAGAATGTCCGCCAGGCAG
CCGTCATGGCCGTGGACAAGGAGCTTCTGGTCAAGCGGCTGCTGCGCGGCTACGGCCAGCCGATCGACACGCTGGAGACG
CCGGAATACGCCGCCTACGATCCGTCGATCAAGGTCGAGCACAATCCGGAAAAGGCCAAGAAATTGCTCGCCGCCTCCGG
CTATTCGACCAAGAAGCCTGCGAAGTTCACCATTCAGACGACCAAGGGCTTCAAGCCCAAGGACTACGAGATGGTGCAGG
CGATCGTCGGCATGTGGCGCAAGGTCGGCATCGAGGCCGAGATCGAGGTCTACGAGATCGCCAAGCATTATGAACTGCGC
GCCGCGCACAAGCTGGCGCCGGCGGCCTTCTACAATTGGGGCAATTCCATCGGCGATCCGACCACCTCGACCGGTTTCGC
CATGTTCGGGCCCTCGCCGCACTCGTCCTGGAAGACCGACGACCTCGACGCCAAGATCGGCCCGCTGTGGGGCGAGAAGG
ACGAGGCCAAGCGCATCGCTGGCTGGAAAGCGGTCGACAAGTACATTGCCGAAGAGGCCTATGTGCTGCCGCTCATCCAG
TACGCACAGCCGATCGTGCACTCGAAGAAGGTCAATGTCGTGCAGCACATTTCCGGTGCGCTGCTGCCGGCCCTGATGAC
CCCGGCCTGA

Upstream 100 bases:

>100_bases
TTTTATCAAGGCGACGAGAGGCAAGGCGCTGCTGCCACGAAGCCTGAACCAATGAACGGACGGTGCCGCGCAAAGACAAT
AACCAACAAGGGGAACGACC

Downstream 100 bases:

>100_bases
TATCGGCCTGAACTTGCCGCGCGCCGTCCATAGCGACGGCGCGCATTTTCTATCAGGCATACGAGCCAGCAGGCTCCTGC
AAAGATTTACATGCTCCTGC

Product: ABC transporter, periplasmic peptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MKINRRELLGYSAAALGVAAIGLPKIAKAAAGELTIAYNVNLPSWDPTTGPSAVNPTIQGLYQSVFDQIISQKPDLSFAP
GLLTEWGWNDDRTKVTMTVREGVKWHDGSPFTPEDVVWSLQRAGDEKTGNPIQFVWKNVNNFKIDGNKITGDVVQFDPVY
FKWMSFLTGYILPKAYYEKVGAEGFEKAPIGTGPYMVEKFERNAFLRLKANPNYWGGKPAFENVTIKFVTDAASRVAEIE
SGSSQVTLEIPYEEYDRLIAKDGLAGSIKNVSDIGMIFFNNKDAMLDKNVRQAAVMAVDKELLVKRLLRGYGQPIDTLET
PEYAAYDPSIKVEHNPEKAKKLLAASGYSTKKPAKFTIQTTKGFKPKDYEMVQAIVGMWRKVGIEAEIEVYEIAKHYELR
AAHKLAPAAFYNWGNSIGDPTTSTGFAMFGPSPHSSWKTDDLDAKIGPLWGEKDEAKRIAGWKAVDKYIAEEAYVLPLIQ
YAQPIVHSKKVNVVQHISGALLPALMTPA

Sequences:

>Translated_509_residues
MKINRRELLGYSAAALGVAAIGLPKIAKAAAGELTIAYNVNLPSWDPTTGPSAVNPTIQGLYQSVFDQIISQKPDLSFAP
GLLTEWGWNDDRTKVTMTVREGVKWHDGSPFTPEDVVWSLQRAGDEKTGNPIQFVWKNVNNFKIDGNKITGDVVQFDPVY
FKWMSFLTGYILPKAYYEKVGAEGFEKAPIGTGPYMVEKFERNAFLRLKANPNYWGGKPAFENVTIKFVTDAASRVAEIE
SGSSQVTLEIPYEEYDRLIAKDGLAGSIKNVSDIGMIFFNNKDAMLDKNVRQAAVMAVDKELLVKRLLRGYGQPIDTLET
PEYAAYDPSIKVEHNPEKAKKLLAASGYSTKKPAKFTIQTTKGFKPKDYEMVQAIVGMWRKVGIEAEIEVYEIAKHYELR
AAHKLAPAAFYNWGNSIGDPTTSTGFAMFGPSPHSSWKTDDLDAKIGPLWGEKDEAKRIAGWKAVDKYIAEEAYVLPLIQ
YAQPIVHSKKVNVVQHISGALLPALMTPA
>Mature_509_residues
MKINRRELLGYSAAALGVAAIGLPKIAKAAAGELTIAYNVNLPSWDPTTGPSAVNPTIQGLYQSVFDQIISQKPDLSFAP
GLLTEWGWNDDRTKVTMTVREGVKWHDGSPFTPEDVVWSLQRAGDEKTGNPIQFVWKNVNNFKIDGNKITGDVVQFDPVY
FKWMSFLTGYILPKAYYEKVGAEGFEKAPIGTGPYMVEKFERNAFLRLKANPNYWGGKPAFENVTIKFVTDAASRVAEIE
SGSSQVTLEIPYEEYDRLIAKDGLAGSIKNVSDIGMIFFNNKDAMLDKNVRQAAVMAVDKELLVKRLLRGYGQPIDTLET
PEYAAYDPSIKVEHNPEKAKKLLAASGYSTKKPAKFTIQTTKGFKPKDYEMVQAIVGMWRKVGIEAEIEVYEIAKHYELR
AAHKLAPAAFYNWGNSIGDPTTSTGFAMFGPSPHSSWKTDDLDAKIGPLWGEKDEAKRIAGWKAVDKYIAEEAYVLPLIQ
YAQPIVHSKKVNVVQHISGALLPALMTPA

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=434, Percent_Identity=26.036866359447, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1789887, Length=522, Percent_Identity=24.904214559387, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081878, Length=523, Percent_Identity=25.4302103250478, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787052, Length=499, Percent_Identity=25.250501002004, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787551, Length=475, Percent_Identity=20.6315789473684, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787762, Length=421, Percent_Identity=22.5653206650831, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56428; Mature: 56428

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINRRELLGYSAAALGVAAIGLPKIAKAAAGELTIAYNVNLPSWDPTTGPSAVNPTIQG
CCCCHHHHHCHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
LYQSVFDQIISQKPDLSFAPGLLTEWGWNDDRTKVTMTVREGVKWHDGSPFTPEDVVWSL
HHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCEEEEEEEECCCEECCCCCCCHHHHHHHH
QRAGDEKTGNPIQFVWKNVNNFKIDGNKITGDVVQFDPVYFKWMSFLTGYILPKAYYEKV
HHCCCCCCCCCHHHEECCCCCEEECCCEEECCEEEECHHHHHHHHHHHHHHCHHHHHHHH
GAEGFEKAPIGTGPYMVEKFERNAFLRLKANPNYWGGKPAFENVTIKFVTDAASRVAEIE
CCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHC
SGSSQVTLEIPYEEYDRLIAKDGLAGSIKNVSDIGMIFFNNKDAMLDKNVRQAAVMAVDK
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHH
ELLVKRLLRGYGQPIDTLETPEYAAYDPSIKVEHNPEKAKKLLAASGYSTKKPAKFTIQT
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCEEEEEE
TKGFKPKDYEMVQAIVGMWRKVGIEAEIEVYEIAKHYELRAAHKLAPAAFYNWGNSIGDP
CCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCC
TTSTGFAMFGPSPHSSWKTDDLDAKIGPLWGEKDEAKRIAGWKAVDKYIAEEAYVLPLIQ
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAQPIVHSKKVNVVQHISGALLPALMTPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKINRRELLGYSAAALGVAAIGLPKIAKAAAGELTIAYNVNLPSWDPTTGPSAVNPTIQG
CCCCHHHHHCHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
LYQSVFDQIISQKPDLSFAPGLLTEWGWNDDRTKVTMTVREGVKWHDGSPFTPEDVVWSL
HHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCEEEEEEEECCCEECCCCCCCHHHHHHHH
QRAGDEKTGNPIQFVWKNVNNFKIDGNKITGDVVQFDPVYFKWMSFLTGYILPKAYYEKV
HHCCCCCCCCCHHHEECCCCCEEECCCEEECCEEEECHHHHHHHHHHHHHHCHHHHHHHH
GAEGFEKAPIGTGPYMVEKFERNAFLRLKANPNYWGGKPAFENVTIKFVTDAASRVAEIE
CCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHC
SGSSQVTLEIPYEEYDRLIAKDGLAGSIKNVSDIGMIFFNNKDAMLDKNVRQAAVMAVDK
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHH
ELLVKRLLRGYGQPIDTLETPEYAAYDPSIKVEHNPEKAKKLLAASGYSTKKPAKFTIQT
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCEEEEEE
TKGFKPKDYEMVQAIVGMWRKVGIEAEIEVYEIAKHYELRAAHKLAPAAFYNWGNSIGDP
CCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCC
TTSTGFAMFGPSPHSSWKTDDLDAKIGPLWGEKDEAKRIAGWKAVDKYIAEEAYVLPLIQ
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAQPIVHSKKVNVVQHISGALLPALMTPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]