Click here to switch to the map view.

The map label for this gene is qor [C]

Identifier: 13471828

GI number: 13471828

Start: 1585407

End: 1586417

Strand: Reverse

Name: qor [C]

Synonym: mll1929

Alternate gene names: 13471828

Gene position: 1586417-1585407 (Counterclockwise)

Preceding gene: 13471830

Following gene: 13471824

Centisome position: 22.55

GC content: 67.95

Gene sequence:

>1011_bases
ATGAAAGCCATCGAACTGAGCCAACCCAGGCTCGACGCCTTCCGCGCCGCCACCGTCGCCACCCCCGAACCGCAGCGCGG
CGAGGTGCTGATCCGCCAGCGTGCGGCCAGCCTCAATTTCGTCGACGTCGCGGTGGCGAGCGGCAATTATCCCGGGCCGA
GCTTTCCACTCATCCCGGTCGCCGACGGCGCCGGTGAGATCGTCGCGCTGGGCGAGGGCGTTACGAGTTTCAGCATGGGC
GATCGCGTCGTCGCCCATGCCAAGCCGCGCTGGATCGGCGGAAGGCCGCGGCCCTACGAAATGACGCAGATGCGCGGCAT
CTCGTTGCCGGGGTCGCTGGCCGAATATGTCGCGCTGCCGGCCAATTCGCTTGTGCCGGTCCCGGCGCATCTCTCCTTCG
AGGCGGCGTCGACGTTGCCGATCGCCGGCACCACGGCATGGAACGCGCTGCGCACCGCCAATGTCGGGCCGGGTTCGGTC
GTCGTGCTGCTCGGCACCGGCGGCGTCTCGATCTTCACCCTGCAGCTTGCCAAGGCGGCTGGCGCCACCGTCATCATCAC
CTCGTCGTCGGACGAGAAGCTGGAGCGGGCGAAGGCGCTGGGCGCCGATCACCTCATCAACTACCGTGCGACGCCGGACT
GGGACGGCAAGGTGCTGGAACTGACCGGCGGCCTTGGCGCCGACCTCGTCGTCGAGACCGGCGGCACCGCGACCTTCGCC
CGCGCCATCAACGCCACGGCGCCCGGCGGCACGCTGTTCACCATCGGTTTCGTCACCGGCGCCGAGGCCACGATCAACCT
GCTGCCGATCATCATCAAGGCCTTGAAAGTGATCGGCAACAACACCGGATCGGTGTCCGACCTTCGCGACGCCGCCCGCG
CCATCGGCGCCGCCGGGATCAAGCCGGTCGTCGACAAGGTGTTTTCACCTGATGACGCGGCCGAAGCCTACACCCACATG
GCTGCCGGCGGCCTGCATTTCGGCAAGCTGGTATTCGGGTTGGAGTGGTAG

Upstream 100 bases:

>100_bases
GCATATCTGGCATTACTCAAATGCAAAATGGAATGATTATCCAGAAATAGCGCAGCAGATAGGTTCACTCAACCATCAAT
CGTCCCACCGGAGTGAAATC

Downstream 100 bases:

>100_bases
GGGCGAACGCGACCGGTCGCGTAATCTCCAGCGCAAAGGGAGATTACGCGCTCCACCCTCAGATCAGCTTCTCCAGCGTG
ATCGGCAAATCCCGCACCCT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKAIELSQPRLDAFRAATVATPEPQRGEVLIRQRAASLNFVDVAVASGNYPGPSFPLIPVADGAGEIVALGEGVTSFSMG
DRVVAHAKPRWIGGRPRPYEMTQMRGISLPGSLAEYVALPANSLVPVPAHLSFEAASTLPIAGTTAWNALRTANVGPGSV
VVLLGTGGVSIFTLQLAKAAGATVIITSSSDEKLERAKALGADHLINYRATPDWDGKVLELTGGLGADLVVETGGTATFA
RAINATAPGGTLFTIGFVTGAEATINLLPIIIKALKVIGNNTGSVSDLRDAARAIGAAGIKPVVDKVFSPDDAAEAYTHM
AAGGLHFGKLVFGLEW

Sequences:

>Translated_336_residues
MKAIELSQPRLDAFRAATVATPEPQRGEVLIRQRAASLNFVDVAVASGNYPGPSFPLIPVADGAGEIVALGEGVTSFSMG
DRVVAHAKPRWIGGRPRPYEMTQMRGISLPGSLAEYVALPANSLVPVPAHLSFEAASTLPIAGTTAWNALRTANVGPGSV
VVLLGTGGVSIFTLQLAKAAGATVIITSSSDEKLERAKALGADHLINYRATPDWDGKVLELTGGLGADLVVETGGTATFA
RAINATAPGGTLFTIGFVTGAEATINLLPIIIKALKVIGNNTGSVSDLRDAARAIGAAGIKPVVDKVFSPDDAAEAYTHM
AAGGLHFGKLVFGLEW
>Mature_336_residues
MKAIELSQPRLDAFRAATVATPEPQRGEVLIRQRAASLNFVDVAVASGNYPGPSFPLIPVADGAGEIVALGEGVTSFSMG
DRVVAHAKPRWIGGRPRPYEMTQMRGISLPGSLAEYVALPANSLVPVPAHLSFEAASTLPIAGTTAWNALRTANVGPGSV
VVLLGTGGVSIFTLQLAKAAGATVIITSSSDEKLERAKALGADHLINYRATPDWDGKVLELTGGLGADLVVETGGTATFA
RAINATAPGGTLFTIGFVTGAEATINLLPIIIKALKVIGNNTGSVSDLRDAARAIGAAGIKPVVDKVFSPDDAAEAYTHM
AAGGLHFGKLVFGLEW

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI28557745, Length=256, Percent_Identity=34.765625, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI22538446, Length=357, Percent_Identity=27.7310924369748, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI22538444, Length=357, Percent_Identity=27.7310924369748, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI194239674, Length=345, Percent_Identity=25.2173913043478, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI13236495, Length=345, Percent_Identity=25.2173913043478, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24308257, Length=356, Percent_Identity=26.9662921348315, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI18379349, Length=233, Percent_Identity=28.755364806867, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI47519420, Length=340, Percent_Identity=27.6470588235294, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI194239676, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI156627571, Length=336, Percent_Identity=26.4880952380952, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790485, Length=258, Percent_Identity=28.2945736434109, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790045, Length=334, Percent_Identity=26.6467065868263, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788073, Length=267, Percent_Identity=31.0861423220974, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082125, Length=338, Percent_Identity=28.1065088757396, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081918, Length=276, Percent_Identity=29.3478260869565, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787863, Length=303, Percent_Identity=25.7425742574257, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI226510992, Length=267, Percent_Identity=25.4681647940075, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788075, Length=315, Percent_Identity=25.3968253968254, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=315, Percent_Identity=26.3492063492064, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562582, Length=318, Percent_Identity=24.8427672955975, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507255, Length=333, Percent_Identity=26.1261261261261, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562876, Length=270, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562878, Length=168, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=286, Percent_Identity=25.1748251748252, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=318, Percent_Identity=24.2138364779874, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322619, Length=306, Percent_Identity=32.0261437908497, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319955, Length=300, Percent_Identity=31.3333333333333, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=318, Percent_Identity=23.8993710691824, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=320, Percent_Identity=22.8125, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=253, Percent_Identity=28.8537549407115, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323980, Length=334, Percent_Identity=25.1497005988024, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323099, Length=315, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737897, Length=258, Percent_Identity=29.4573643410853, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17137530, Length=261, Percent_Identity=27.2030651340996, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 34598; Mature: 34598

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIELSQPRLDAFRAATVATPEPQRGEVLIRQRAASLNFVDVAVASGNYPGPSFPLIPV
CCCCCCCCCCHHHHHHEEECCCCCCCCCEEEEHHHCCCCEEEEEEECCCCCCCCCCEEEE
ADGAGEIVALGEGVTSFSMGDRVVAHAKPRWIGGRPRPYEMTQMRGISLPGSLAEYVALP
CCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCC
ANSLVPVPAHLSFEAASTLPIAGTTAWNALRTANVGPGSVVVLLGTGGVSIFTLQLAKAA
CCCCCCCCCCCEECCCCCCCCCCCCHHHHHEECCCCCCEEEEEEECCCCEEEEEEEHHHC
GATVIITSSSDEKLERAKALGADHLINYRATPDWDGKVLELTGGLGADLVVETGGTATFA
CCEEEEECCCHHHHHHHHHCCHHHEEEECCCCCCCCEEEEEECCCCCEEEEECCCCEEEH
RAINATAPGGTLFTIGFVTGAEATINLLPIIIKALKVIGNNTGSVSDLRDAARAIGAAGI
HHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
KPVVDKVFSPDDAAEAYTHMAAGGLHFGKLVFGLEW
HHHHHHHCCCCHHHHHHHHHHCCCCEEEHEEEEECC
>Mature Secondary Structure
MKAIELSQPRLDAFRAATVATPEPQRGEVLIRQRAASLNFVDVAVASGNYPGPSFPLIPV
CCCCCCCCCCHHHHHHEEECCCCCCCCCEEEEHHHCCCCEEEEEEECCCCCCCCCCEEEE
ADGAGEIVALGEGVTSFSMGDRVVAHAKPRWIGGRPRPYEMTQMRGISLPGSLAEYVALP
CCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCC
ANSLVPVPAHLSFEAASTLPIAGTTAWNALRTANVGPGSVVVLLGTGGVSIFTLQLAKAA
CCCCCCCCCCCEECCCCCCCCCCCCHHHHHEECCCCCCEEEEEEECCCCEEEEEEEHHHC
GATVIITSSSDEKLERAKALGADHLINYRATPDWDGKVLELTGGLGADLVVETGGTATFA
CCEEEEECCCHHHHHHHHHCCHHHEEEECCCCCCCCEEEEEECCCCCEEEEECCCCEEEH
RAINATAPGGTLFTIGFVTGAEATINLLPIIIKALKVIGNNTGSVSDLRDAARAIGAAGI
HHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
KPVVDKVFSPDDAAEAYTHMAAGGLHFGKLVFGLEW
HHHHHHHCCCCHHHHHHHHHHCCCCEEEHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]