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The map label for this gene is prmA

Identifier: 13471532

GI number: 13471532

Start: 1270859

End: 1271731

Strand: Direct

Name: prmA

Synonym: mlr1533

Alternate gene names: 13471532

Gene position: 1270859-1271731 (Clockwise)

Preceding gene: 13471531

Following gene: 13471534

Centisome position: 18.06

GC content: 65.29

Gene sequence:

>873_bases
ATGACCCAGACGCGGCTGCATTTCACCACCGGCAAGATCGAGGCTGAGCGCATTTTCGCGGCGCTTGAGCTGGCCTTCGA
GGATGAAGGCCTGCCGATCGCCGTGCTCGAGGTCGACGAAGACCAGGACATCCACGAGGTCTCGCTCTATGCCGATGGCG
ATGTCGATACGGTCGAGGCGCGGGTCAAGGACATTCTCGCCGGCCTTGCTTTGTCGAAGCCGGTCGAGCGCGAAGTGCTG
CCTGACATCGACTGGGTGGCGCGTTCGCTGGAGGGCCTGAAGCCAGTGCGCGCCGGCCGTTTCTTCGTCCACGGCGCGCA
TGACCGAAGGAAGCGCCACAGCGGCGAACTCGCCATCGAGATCGAGGCCGGCCTTGCCTTCGGCACCGGCCATCACGGCA
CCACATCAGGCTGCCTGGAAATGCTGGAGAAAGTGGTGCGGCGCGAGCATCCGCGCAATGCGCTCGACCTCGGCACCGGC
AGCGCCGTGCTGGCCATCGCCGTCGCCAAGCTGGCGCATATTCCGGTGCTCGCCACCGACATCGACCCGGTGGCGGTGAA
GGTCGCCGCCGCCAATGCGCGGCTCAATCACGTCAAGGCGCTCATCGAAACGGTTACCGCACCGGGCTTTCACCACCCGA
TCTTCGGCAGGCGTGCCCCCTTCGATCTGATCGTCGCCAACATATTGGCGCGGCCGCTGATGCGGCTGGCGCCGCAAATG
GCCGGGCACATCGCACTTGGCGGCTCGATCGTCCTGTCAGGCATTCTCGAGCGCCAGCGCGACGCCGTCATCTCGGCCTA
TGTCGGCCAGAATTTCCGGCACGTGCGCACCTTGTACCGCGAAGGCTGGGTGACGATCCACCTCAAGCACTGA

Upstream 100 bases:

>100_bases
CCAAGGGCGACTTTGCCGGCACGATCGCCTATGGCGAAAGCGCCAGCGCCGCCGTGGAGAAGCTGAAGCGCCTCGCGGCC
AAGGGTTGACAAGAATTCAT

Downstream 100 bases:

>100_bases
GACCGGCAAGGCAATTGCCGATCCCCGACAGTCCCAACACCTAGAACTTGATGCCCAGATTGGCCTTGAACCCATTGTCG
AAGGCATTCCGCCCAAACTG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTQTRLHFTTGKIEAERIFAALELAFEDEGLPIAVLEVDEDQDIHEVSLYADGDVDTVEARVKDILAGLALSKPVEREVL
PDIDWVARSLEGLKPVRAGRFFVHGAHDRRKRHSGELAIEIEAGLAFGTGHHGTTSGCLEMLEKVVRREHPRNALDLGTG
SAVLAIAVAKLAHIPVLATDIDPVAVKVAAANARLNHVKALIETVTAPGFHHPIFGRRAPFDLIVANILARPLMRLAPQM
AGHIALGGSIVLSGILERQRDAVISAYVGQNFRHVRTLYREGWVTIHLKH

Sequences:

>Translated_290_residues
MTQTRLHFTTGKIEAERIFAALELAFEDEGLPIAVLEVDEDQDIHEVSLYADGDVDTVEARVKDILAGLALSKPVEREVL
PDIDWVARSLEGLKPVRAGRFFVHGAHDRRKRHSGELAIEIEAGLAFGTGHHGTTSGCLEMLEKVVRREHPRNALDLGTG
SAVLAIAVAKLAHIPVLATDIDPVAVKVAAANARLNHVKALIETVTAPGFHHPIFGRRAPFDLIVANILARPLMRLAPQM
AGHIALGGSIVLSGILERQRDAVISAYVGQNFRHVRTLYREGWVTIHLKH
>Mature_289_residues
TQTRLHFTTGKIEAERIFAALELAFEDEGLPIAVLEVDEDQDIHEVSLYADGDVDTVEARVKDILAGLALSKPVEREVLP
DIDWVARSLEGLKPVRAGRFFVHGAHDRRKRHSGELAIEIEAGLAFGTGHHGTTSGCLEMLEKVVRREHPRNALDLGTGS
AVLAIAVAKLAHIPVLATDIDPVAVKVAAANARLNHVKALIETVTAPGFHHPIFGRRAPFDLIVANILARPLMRLAPQMA
GHIALGGSIVLSGILERQRDAVISAYVGQNFRHVRTLYREGWVTIHLKH

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=252, Percent_Identity=31.7460317460317, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_RHILO (Q98KD0)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103098.1
- ProteinModelPortal:   Q98KD0
- SMR:   Q98KD0
- GeneID:   1225761
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr1533
- NMPDR:   fig|266835.1.peg.1203
- HOGENOM:   HBG584653
- OMA:   GHHGTTL
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31680; Mature: 31549

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTRLHFTTGKIEAERIFAALELAFEDEGLPIAVLEVDEDQDIHEVSLYADGDVDTVEA
CCCCEEEEEECCHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHH
RVKDILAGLALSKPVEREVLPDIDWVARSLEGLKPVRAGRFFVHGAHDRRKRHSGELAIE
HHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCHHCCEEEEECCHHHHHHCCCCEEEE
IEAGLAFGTGHHGTTSGCLEMLEKVVRREHPRNALDLGTGSAVLAIAVAKLAHIPVLATD
EECCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
IDPVAVKVAAANARLNHVKALIETVTAPGFHHPIFGRRAPFDLIVANILARPLMRLAPQM
CCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGHIALGGSIVLSGILERQRDAVISAYVGQNFRHVRTLYREGWVTIHLKH
HCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEC
>Mature Secondary Structure 
TQTRLHFTTGKIEAERIFAALELAFEDEGLPIAVLEVDEDQDIHEVSLYADGDVDTVEA
CCCEEEEEECCHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHH
RVKDILAGLALSKPVEREVLPDIDWVARSLEGLKPVRAGRFFVHGAHDRRKRHSGELAIE
HHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCHHCCEEEEECCHHHHHHCCCCEEEE
IEAGLAFGTGHHGTTSGCLEMLEKVVRREHPRNALDLGTGSAVLAIAVAKLAHIPVLATD
EECCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
IDPVAVKVAAANARLNHVKALIETVTAPGFHHPIFGRRAPFDLIVANILARPLMRLAPQM
CCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGHIALGGSIVLSGILERQRDAVISAYVGQNFRHVRTLYREGWVTIHLKH
HCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968