Click here to switch to the map view.

The map label for this gene is yqhT [H]

Identifier: 13471534

GI number: 13471534

Start: 1275483

End: 1277276

Strand: Direct

Name: yqhT [H]

Synonym: mlr1535

Alternate gene names: 13471534

Gene position: 1275483-1277276 (Clockwise)

Preceding gene: 13471532

Following gene: 13471540

Centisome position: 18.13

GC content: 66.67

Gene sequence:

>1794_bases
GTGGCGGCGCTGCGCCAATGGCTGGCGGCCAATGGCCTCGACGGCTTTATCGTCCCGCGCGCCGACGAGCATCAGGGCGA
ATATGTCGCCGATCGTTCGGCGCGGCTGAAATGGCTGACCGGTTTCAGCGGCTCGGCCGGTGTCGCCATCGTGCTGCGCG
ACCGCGCCTTCATCTTCGTCGACGGGCGCTACACGCTGCAGGTGCGCAGCGAGGTCGATCTCGACATTTTTTCGGTCGAA
AGCCTGGTCGACAACCCGCCCGCTGTCTGGCTCAAGGACAATATCGGCAAGGGCGCGCGGCTGGGCTTCGATCCATGGCT
GCACACGATCGGCGAGGTCAAGGCGCTGCAGACCTCGGCCGACAAGACCGGCGCGGTGCTGGTGCCGCTCGAGAAAAACC
CGATCGACATCATCTGGAAGGACCAGCCCGCCGCGCCGGTGACGCCGGTCGAGCTGCACCCGATCGGCTTTGCCGGCGAA
CTCGCCAAGGACAAGCTGGCGCGGCTGGCGACCGCGATCGGCAAGGACGGCGCCACCCATGCGGTGCTGACCGACCCCTC
CTCCATCGCCTGGACCTTCAACATCCGTGGCGGTGACGTGCCGCACACGCCGCTGGCGCTCGGCTTCGCCATCCTCGCAG
CGGATGGGTCGCACCAGTTGTTCATGGACAGCCGCAAATTCTCGCGCCAGGTTGCGGCTTATCTCACCCAACTTGCCGAT
CCGCACGAGCCTGGCGAATTCGAGGCGGCGATCGCAGCGCTTGCCAAGGGTGGCGCGAAAATCGCGCTCGACCCGGTGCT
GGCGGCCGACCGGCTGCGCATGCTGGTCGAGGACAATGGCGGCACGGTGGTTGCTGCGCCCGATCCGGCCCGCATCCCGC
GTGCCACCAAGAACCAGGCCGAAATCAACGGCTCGCGCGCCGCGCACCGTCGTGACGGCGCGGCGGTGGCCAAGCTTCTG
TGCTGGCTAGAGCGGCAAAAACCCGGCTCGCTCGACGAGATCGCGGTCGTCACCAGGCTGGAGGAGAGCCGCCGGCAGAC
CGGCGAGGAAACGCAAATGCCGCTGCGCGACGTGTCCTTCGACACCATTTCCGGCGCCGGCCCGAACGGCGCCATCATGC
ATTACCGCGTGTCGCGCGCCACCAGCCGAAAGCTGCAGGCGGGCGAGCTGTTCCTGCTCGATTCCGGCGCGCAGTATCAG
GACGGCACCACCGACATCACCCGCACCGTGCCGATCGGCCAGCCGACCGAGGAGATGCGCGAACGCTTCACGCTGGTGCT
GAAGGGCATGATCGGCATTTCCACGCTGCGCTTTCCCGCCGGCACGCGCGGCTCGGAGATCGACGCCATCGCCCGCATGG
CGCTGTGGAAGCATGGCTGCGACTTCGCCCACGGCACCGGCCATGGCGTCGGCTCTTATCTCGCCGTGCATGAAGGTCCG
CAGCGCATTGCCCGCACCGGCACCGAAAAGCTGCTCGAAGGCATGATGCTGTCCAACGAACCCGGCTATTACAAGGAAGG
CGCCTACGGCATCCGCATCGAAAACCTCATCCTGGTGACGCCGGCCGAACAGATCGAGGGCGGCGATATCGCCATGCATG
GCTTCGAGACGCTGACGCTGGCGCCGATCGACATCAGGCTGGTGCGTTCAGACCTCTTGACGCGCGAGGAGCTGCATTGG
CTTGACACCTACCATGCCCGGGTGCTGGCCGAGATCGGGCCGATGCTCGACGGCGAGACCCTGGCCTGGCTGGAAAAAGC
GACAGCGCCGCTGCCGCACGACGCCAAGATTTGA

Upstream 100 bases:

>100_bases
GATTTCCGGACCCATAGGCTACGGTCGCGCAGACATCAGGAGGCCCATCATGTTCCAGACCTTCGATTCCGCGGGCGACC
CTTCGGTTGGCAAGCCGCGC

Downstream 100 bases:

>100_bases
TTTTCTGACGCACCGGGGGCGTATCGAGATTCAGGGCAGGACGAGCCGGAGTCGAAGACGGGCGCAAGGCAACCAAACAA
GGTGGTTTCCGAGAACCGGA

Product: aminopeptidase P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MAALRQWLAANGLDGFIVPRADEHQGEYVADRSARLKWLTGFSGSAGVAIVLRDRAFIFVDGRYTLQVRSEVDLDIFSVE
SLVDNPPAVWLKDNIGKGARLGFDPWLHTIGEVKALQTSADKTGAVLVPLEKNPIDIIWKDQPAAPVTPVELHPIGFAGE
LAKDKLARLATAIGKDGATHAVLTDPSSIAWTFNIRGGDVPHTPLALGFAILAADGSHQLFMDSRKFSRQVAAYLTQLAD
PHEPGEFEAAIAALAKGGAKIALDPVLAADRLRMLVEDNGGTVVAAPDPARIPRATKNQAEINGSRAAHRRDGAAVAKLL
CWLERQKPGSLDEIAVVTRLEESRRQTGEETQMPLRDVSFDTISGAGPNGAIMHYRVSRATSRKLQAGELFLLDSGAQYQ
DGTTDITRTVPIGQPTEEMRERFTLVLKGMIGISTLRFPAGTRGSEIDAIARMALWKHGCDFAHGTGHGVGSYLAVHEGP
QRIARTGTEKLLEGMMLSNEPGYYKEGAYGIRIENLILVTPAEQIEGGDIAMHGFETLTLAPIDIRLVRSDLLTREELHW
LDTYHARVLAEIGPMLDGETLAWLEKATAPLPHDAKI

Sequences:

>Translated_597_residues
MAALRQWLAANGLDGFIVPRADEHQGEYVADRSARLKWLTGFSGSAGVAIVLRDRAFIFVDGRYTLQVRSEVDLDIFSVE
SLVDNPPAVWLKDNIGKGARLGFDPWLHTIGEVKALQTSADKTGAVLVPLEKNPIDIIWKDQPAAPVTPVELHPIGFAGE
LAKDKLARLATAIGKDGATHAVLTDPSSIAWTFNIRGGDVPHTPLALGFAILAADGSHQLFMDSRKFSRQVAAYLTQLAD
PHEPGEFEAAIAALAKGGAKIALDPVLAADRLRMLVEDNGGTVVAAPDPARIPRATKNQAEINGSRAAHRRDGAAVAKLL
CWLERQKPGSLDEIAVVTRLEESRRQTGEETQMPLRDVSFDTISGAGPNGAIMHYRVSRATSRKLQAGELFLLDSGAQYQ
DGTTDITRTVPIGQPTEEMRERFTLVLKGMIGISTLRFPAGTRGSEIDAIARMALWKHGCDFAHGTGHGVGSYLAVHEGP
QRIARTGTEKLLEGMMLSNEPGYYKEGAYGIRIENLILVTPAEQIEGGDIAMHGFETLTLAPIDIRLVRSDLLTREELHW
LDTYHARVLAEIGPMLDGETLAWLEKATAPLPHDAKI
>Mature_596_residues
AALRQWLAANGLDGFIVPRADEHQGEYVADRSARLKWLTGFSGSAGVAIVLRDRAFIFVDGRYTLQVRSEVDLDIFSVES
LVDNPPAVWLKDNIGKGARLGFDPWLHTIGEVKALQTSADKTGAVLVPLEKNPIDIIWKDQPAAPVTPVELHPIGFAGEL
AKDKLARLATAIGKDGATHAVLTDPSSIAWTFNIRGGDVPHTPLALGFAILAADGSHQLFMDSRKFSRQVAAYLTQLADP
HEPGEFEAAIAALAKGGAKIALDPVLAADRLRMLVEDNGGTVVAAPDPARIPRATKNQAEINGSRAAHRRDGAAVAKLLC
WLERQKPGSLDEIAVVTRLEESRRQTGEETQMPLRDVSFDTISGAGPNGAIMHYRVSRATSRKLQAGELFLLDSGAQYQD
GTTDITRTVPIGQPTEEMRERFTLVLKGMIGISTLRFPAGTRGSEIDAIARMALWKHGCDFAHGTGHGVGSYLAVHEGPQ
RIARTGTEKLLEGMMLSNEPGYYKEGAYGIRIENLILVTPAEQIEGGDIAMHGFETLTLAPIDIRLVRSDLLTREELHWL
DTYHARVLAEIGPMLDGETLAWLEKATAPLPHDAKI

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=604, Percent_Identity=37.5827814569536, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI93141226, Length=607, Percent_Identity=33.4431630971993, Blast_Score=345, Evalue=5e-95,
Organism=Homo sapiens, GI264681565, Length=604, Percent_Identity=35.7615894039735, Blast_Score=343, Evalue=2e-94,
Organism=Escherichia coli, GI1788728, Length=253, Percent_Identity=32.0158102766798, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789275, Length=194, Percent_Identity=30.4123711340206, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17509539, Length=598, Percent_Identity=35.4515050167224, Blast_Score=324, Evalue=8e-89,
Organism=Caenorhabditis elegans, GI25149105, Length=601, Percent_Identity=29.783693843594, Blast_Score=252, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6322999, Length=654, Percent_Identity=32.4159021406728, Blast_Score=308, Evalue=2e-84,
Organism=Drosophila melanogaster, GI17137632, Length=603, Percent_Identity=32.5041459369818, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI161078230, Length=589, Percent_Identity=30.2207130730051, Blast_Score=253, Evalue=4e-67,
Organism=Drosophila melanogaster, GI21357287, Length=589, Percent_Identity=30.2207130730051, Blast_Score=253, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 64749; Mature: 64617

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALRQWLAANGLDGFIVPRADEHQGEYVADRSARLKWLTGFSGSAGVAIVLRDRAFIFV
CHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEECCEEEEE
DGRYTLQVRSEVDLDIFSVESLVDNPPAVWLKDNIGKGARLGFDPWLHTIGEVKALQTSA
CCEEEEEECCCCCEEEEEHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
DKTGAVLVPLEKNPIDIIWKDQPAAPVTPVELHPIGFAGELAKDKLARLATAIGKDGATH
CCCCEEEEEECCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCE
AVLTDPSSIAWTFNIRGGDVPHTPLALGFAILAADGSHQLFMDSRKFSRQVAAYLTQLAD
EEEECCCCEEEEEEECCCCCCCCHHHHEEEEEECCCCCEEEECHHHHHHHHHHHHHHHCC
PHEPGEFEAAIAALAKGGAKIALDPVLAADRLRMLVEDNGGTVVAAPDPARIPRATKNQA
CCCCCHHHHHHHHHHCCCCEEEECHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCH
EINGSRAAHRRDGAAVAKLLCWLERQKPGSLDEIAVVTRLEESRRQTGEETQMPLRDVSF
HCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCHHHCCC
DTISGAGPNGAIMHYRVSRATSRKLQAGELFLLDSGAQYQDGTTDITRTVPIGQPTEEMR
CCCCCCCCCCCEEEEEECHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCHHHHH
ERFTLVLKGMIGISTLRFPAGTRGSEIDAIARMALWKHGCDFAHGTGHGVGSYLAVHEGP
HHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCH
QRIARTGTEKLLEGMMLSNEPGYYKEGAYGIRIENLILVTPAEQIEGGDIAMHGFETLTL
HHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCHHHCCCCCEEEECCEEEEE
APIDIRLVRSDLLTREELHWLDTYHARVLAEIGPMLDGETLAWLEKATAPLPHDAKI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AALRQWLAANGLDGFIVPRADEHQGEYVADRSARLKWLTGFSGSAGVAIVLRDRAFIFV
HHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEECCEEEEE
DGRYTLQVRSEVDLDIFSVESLVDNPPAVWLKDNIGKGARLGFDPWLHTIGEVKALQTSA
CCEEEEEECCCCCEEEEEHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
DKTGAVLVPLEKNPIDIIWKDQPAAPVTPVELHPIGFAGELAKDKLARLATAIGKDGATH
CCCCEEEEEECCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCE
AVLTDPSSIAWTFNIRGGDVPHTPLALGFAILAADGSHQLFMDSRKFSRQVAAYLTQLAD
EEEECCCCEEEEEEECCCCCCCCHHHHEEEEEECCCCCEEEECHHHHHHHHHHHHHHHCC
PHEPGEFEAAIAALAKGGAKIALDPVLAADRLRMLVEDNGGTVVAAPDPARIPRATKNQA
CCCCCHHHHHHHHHHCCCCEEEECHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCH
EINGSRAAHRRDGAAVAKLLCWLERQKPGSLDEIAVVTRLEESRRQTGEETQMPLRDVSF
HCCCCHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCHHHCCC
DTISGAGPNGAIMHYRVSRATSRKLQAGELFLLDSGAQYQDGTTDITRTVPIGQPTEEMR
CCCCCCCCCCCEEEEEECHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCHHHHH
ERFTLVLKGMIGISTLRFPAGTRGSEIDAIARMALWKHGCDFAHGTGHGVGSYLAVHEGP
HHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCH
QRIARTGTEKLLEGMMLSNEPGYYKEGAYGIRIENLILVTPAEQIEGGDIAMHGFETLTL
HHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCHHHCCCCCEEEECCEEEEE
APIDIRLVRSDLLTREELHWLDTYHARVLAEIGPMLDGETLAWLEKATAPLPHDAKI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]