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The map label for this gene is cobJ [H]

Identifier: 13471415

GI number: 13471415

Start: 1157125

End: 1157889

Strand: Direct

Name: cobJ [H]

Synonym: mlr1381

Alternate gene names: 13471415

Gene position: 1157125-1157889 (Clockwise)

Preceding gene: 13471414

Following gene: 13471417

Centisome position: 16.45

GC content: 68.24

Gene sequence:

>765_bases
ATGAGCGGCCGTCTCACCGTCATCGGCCTCGGGCCTGGCAACGCCGACCAGGTCACCCCGGAAGCCAGCCGCGCCGTGGC
CGAGGCAAAATTCTTCTATGGCTACAAGCCTTATCTCGACCGGCTGGATCTGCGCCCGGACCAGACCCGTGTCGCCTCCG
ACAACCGCGAGGAGCTCGCCCGCTCCAAGGATGCCTTGATCAAGGCCGCCGAGGGCCATGAGGTCGCCGTGGTTTCCGGC
GGCGATCCCGGCGTCTTTGCCATGGCGGCCGCCGTCTGCGAGGCGATCGAGGCCGGCCCGGCCGAATGGCGCGCGGTCGA
TGTCGCCGTCGTGCCCGGCATCACCGCAATGCTCGCCGTTGCCGCCCGCATCGGCGCGCCGCTCGGCCATGATTTCTGCG
CCATCTCGCTGTCCGACAATCTGAAGCCGTGGGAGCTGATCGAACTGCGCCTCCTGGCGGCGGCCGGCGCCGGCTTCGTC
ATCGCGCTCTACAACCCGATCAGCAAGGCGCGCCCCTGGCAGCTTGGCCGCGCCTTCGAATGCCTGACCGCGATCCTGCC
CGGCACCACGCCGGTGATTTTCGGCCGCGCCGCCGGCCGTCCGGACGAGCGCATCGAGGTTTATCTGCTGGCTGACGTCG
ACGCGCAAAAGGCCGACATGGCGACCTGCATCATCATCGGCTCGCCGGAAACACGCATCATCAAGCGCGGCGATAAACGG
GCGCTGGTCTACACCCCGCGCTCCGCAGCGGGCTCGACAAAATGA

Upstream 100 bases:

>100_bases
CGACAAAGCTCGCCGACAAACGGGACGACAAGGCGCCCTACTTCGCCATCATATTGGTCGCCGGCTGGTCCGGCCGGCCC
GGCGCGCTAGGGGCACAGTC

Downstream 100 bases:

>100_bases
TCGACCATCGCGGCGAGTTCATCGACGGTTTCAGCCGAAGGCACGTCCGGCAAAGTCGGCCTGCGGACCATGACCACGTC
GATGCCAAGCGCTCGCGCGG

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSGRLTVIGLGPGNADQVTPEASRAVAEAKFFYGYKPYLDRLDLRPDQTRVASDNREELARSKDALIKAAEGHEVAVVSG
GDPGVFAMAAAVCEAIEAGPAEWRAVDVAVVPGITAMLAVAARIGAPLGHDFCAISLSDNLKPWELIELRLLAAAGAGFV
IALYNPISKARPWQLGRAFECLTAILPGTTPVIFGRAAGRPDERIEVYLLADVDAQKADMATCIIIGSPETRIIKRGDKR
ALVYTPRSAAGSTK

Sequences:

>Translated_254_residues
MSGRLTVIGLGPGNADQVTPEASRAVAEAKFFYGYKPYLDRLDLRPDQTRVASDNREELARSKDALIKAAEGHEVAVVSG
GDPGVFAMAAAVCEAIEAGPAEWRAVDVAVVPGITAMLAVAARIGAPLGHDFCAISLSDNLKPWELIELRLLAAAGAGFV
IALYNPISKARPWQLGRAFECLTAILPGTTPVIFGRAAGRPDERIEVYLLADVDAQKADMATCIIIGSPETRIIKRGDKR
ALVYTPRSAAGSTK
>Mature_253_residues
SGRLTVIGLGPGNADQVTPEASRAVAEAKFFYGYKPYLDRLDLRPDQTRVASDNREELARSKDALIKAAEGHEVAVVSGG
DPGVFAMAAAVCEAIEAGPAEWRAVDVAVVPGITAMLAVAARIGAPLGHDFCAISLSDNLKPWELIELRLLAAAGAGFVI
ALYNPISKARPWQLGRAFECLTAILPGTTPVIFGRAAGRPDERIEVYLLADVDAQKADMATCIIIGSPETRIIKRGDKRA
LVYTPRSAAGSTK

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 26911; Mature: 26780

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRLTVIGLGPGNADQVTPEASRAVAEAKFFYGYKPYLDRLDLRPDQTRVASDNREELA
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHCCCCHHHHH
RSKDALIKAAEGHEVAVVSGGDPGVFAMAAAVCEAIEAGPAEWRAVDVAVVPGITAMLAV
HHHHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHH
AARIGAPLGHDFCAISLSDNLKPWELIELRLLAAAGAGFVIALYNPISKARPWQLGRAFE
HHHHCCCCCCCEEEEEECCCCCCHHHHHEEEEECCCCCEEEEEECCCCCCCCCCHHHHHH
CLTAILPGTTPVIFGRAAGRPDERIEVYLLADVDAQKADMATCIIIGSPETRIIKRGDKR
HHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCEEEECCCCE
ALVYTPRSAAGSTK
EEEECCCCCCCCCC
>Mature Secondary Structure 
SGRLTVIGLGPGNADQVTPEASRAVAEAKFFYGYKPYLDRLDLRPDQTRVASDNREELA
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHCCCCHHHHH
RSKDALIKAAEGHEVAVVSGGDPGVFAMAAAVCEAIEAGPAEWRAVDVAVVPGITAMLAV
HHHHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHH
AARIGAPLGHDFCAISLSDNLKPWELIELRLLAAAGAGFVIALYNPISKARPWQLGRAFE
HHHHCCCCCCCEEEEEECCCCCCHHHHHEEEEECCCCCEEEEEECCCCCCCCCCHHHHHH
CLTAILPGTTPVIFGRAAGRPDERIEVYLLADVDAQKADMATCIIIGSPETRIIKRGDKR
HHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCEEEECCCCE
ALVYTPRSAAGSTK
EEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]