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The map label for this gene is cobI [H]

Identifier: 13471414

GI number: 13471414

Start: 1156358

End: 1157128

Strand: Direct

Name: cobI [H]

Synonym: mlr1380

Alternate gene names: 13471414

Gene position: 1156358-1157128 (Clockwise)

Preceding gene: 13471413

Following gene: 13471415

Centisome position: 16.43

GC content: 63.94

Gene sequence:

>771_bases
GTGAACGCGCTTCCCAATGCCAATTCACGGGGCAAGCTCGTCGGCGTCGGTACCGGTCCGGGTGACCCCGAACTGTTGAC
GCTGAAGGCCGCGCGCGCCCTAGCCGAGGCCGATGTCGTCGCCTATTTTGCCAAGCGCGGCAACAACAGCAATGCGCGGG
CCATCGTCGAGGCGCGCTTCCGGCCGGATATGCTGGAACTGCCGCTGCTCTATCCCGTCACCACCGAAATCGACAAGGAT
CACGACGACTACCGCTCGCAGATCACTGGTTTCTACGAGGAGTCGGCGCAGAAGGTCGCCGAACACCTCGAAGCCGGCAA
AATGGTTGCCGTCCTGTCCGAAGGCGATCCGCTGTTCTACGGCTCCTATATGCATCTGCATGTGCGCCTCGCCCATCGTT
TCCCCACGGAGGTCATCCCCGGCATCACCGCCATGTCCGGCTGCTGGTCGCAGACCGGTGTGCCGATCGTACAGGGCGAT
GATGTGCTGACCGTATTGCCCGGCACGATGAGCGAGTTCGAGCTGACCCGCCGGCTGGCCGACACCGATGCCGCCGTCAT
CATGAAGGTCGGCCGCAACCTGCCCAAGATTAGGCGTGCGCTGGAAGTCACCGGTAAGCTGACTCGCGCCGTCTATGTCG
AGCGCGGCACCATGGCCGGCAGCGTTTCGACAAAGCTCGCCGACAAACGGGACGACAAGGCGCCCTACTTCGCCATCATA
TTGGTCGCCGGCTGGTCCGGCCGGCCCGGCGCGCTAGGGGCACAGTCATGA

Upstream 100 bases:

>100_bases
CCGAGAATTCTTATGGCGTGCCCTATGCCATCGTCCGCGGCCGGCTCGGCGGCAGCGCCATGACCGCAGCCGCGCTCAAT
TCCCTGGCGAGGCCCGGCCT

Downstream 100 bases:

>100_bases
GCGGCCGTCTCACCGTCATCGGCCTCGGGCCTGGCAACGCCGACCAGGTCACCCCGGAAGCCAGCCGCGCCGTGGCCGAG
GCAAAATTCTTCTATGGCTA

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNALPNANSRGKLVGVGTGPGDPELLTLKAARALAEADVVAYFAKRGNNSNARAIVEARFRPDMLELPLLYPVTTEIDKD
HDDYRSQITGFYEESAQKVAEHLEAGKMVAVLSEGDPLFYGSYMHLHVRLAHRFPTEVIPGITAMSGCWSQTGVPIVQGD
DVLTVLPGTMSEFELTRRLADTDAAVIMKVGRNLPKIRRALEVTGKLTRAVYVERGTMAGSVSTKLADKRDDKAPYFAII
LVAGWSGRPGALGAQS

Sequences:

>Translated_256_residues
MNALPNANSRGKLVGVGTGPGDPELLTLKAARALAEADVVAYFAKRGNNSNARAIVEARFRPDMLELPLLYPVTTEIDKD
HDDYRSQITGFYEESAQKVAEHLEAGKMVAVLSEGDPLFYGSYMHLHVRLAHRFPTEVIPGITAMSGCWSQTGVPIVQGD
DVLTVLPGTMSEFELTRRLADTDAAVIMKVGRNLPKIRRALEVTGKLTRAVYVERGTMAGSVSTKLADKRDDKAPYFAII
LVAGWSGRPGALGAQS
>Mature_256_residues
MNALPNANSRGKLVGVGTGPGDPELLTLKAARALAEADVVAYFAKRGNNSNARAIVEARFRPDMLELPLLYPVTTEIDKD
HDDYRSQITGFYEESAQKVAEHLEAGKMVAVLSEGDPLFYGSYMHLHVRLAHRFPTEVIPGITAMSGCWSQTGVPIVQGD
DVLTVLPGTMSEFELTRRLADTDAAVIMKVGRNLPKIRRALEVTGKLTRAVYVERGTMAGSVSTKLADKRDDKAPYFAII
LVAGWSGRPGALGAQS

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27712; Mature: 27712

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPNANSRGKLVGVGTGPGDPELLTLKAARALAEADVVAYFAKRGNNSNARAIVEARF
CCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
RPDMLELPLLYPVTTEIDKDHDDYRSQITGFYEESAQKVAEHLEAGKMVAVLSEGDPLFY
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEE
GSYMHLHVRLAHRFPTEVIPGITAMSGCWSQTGVPIVQGDDVLTVLPGTMSEFELTRRLA
CCEEEEEEEEHHHCCHHHHCCCHHHHCCHHHCCCEEEECCCEEEECCCCHHHHHHHHHHH
DTDAAVIMKVGRNLPKIRRALEVTGKLTRAVYVERGTMAGSVSTKLADKRDDKAPYFAII
CCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEE
LVAGWSGRPGALGAQS
EEECCCCCCCCCCCCC
>Mature Secondary Structure
MNALPNANSRGKLVGVGTGPGDPELLTLKAARALAEADVVAYFAKRGNNSNARAIVEARF
CCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
RPDMLELPLLYPVTTEIDKDHDDYRSQITGFYEESAQKVAEHLEAGKMVAVLSEGDPLFY
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEE
GSYMHLHVRLAHRFPTEVIPGITAMSGCWSQTGVPIVQGDDVLTVLPGTMSEFELTRRLA
CCEEEEEEEEHHHCCHHHHCCCHHHHCCHHHCCCEEEECCCEEEECCCCHHHHHHHHHHH
DTDAAVIMKVGRNLPKIRRALEVTGKLTRAVYVERGTMAGSVSTKLADKRDDKAPYFAII
CCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEE
LVAGWSGRPGALGAQS
EEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]