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The map label for this gene is cobL [H]

Identifier: 13471417

GI number: 13471417

Start: 1158616

End: 1159851

Strand: Direct

Name: cobL [H]

Synonym: mlr1383

Alternate gene names: 13471417

Gene position: 1158616-1159851 (Clockwise)

Preceding gene: 13471415

Following gene: 13471418

Centisome position: 16.47

GC content: 66.26

Gene sequence:

>1236_bases
ATGCCTGCTGAAAGTTCGCGCGGCGCCGGACCGAAATGGCTGACGGTGATCGGCATCGGCGAGGACGGTTTAGCGGGTCT
CGGCGACGAGGCCAAGCAGCGGATTGCCAAGGCCGAGATCATCTTCGGCGGCAAGCGGCACCTGGCGCTGGTCGCGTCCT
TCGCCAAGGGCGAGCCACGTCCCTGGCCGGTGCCTTTCGATGCCGGGATGGCCGACGTGCTGGCCCTAGCCGGCAGAAAC
GTCTGTGTGCTCGCCTCCGGCGATCCTTTTTTCCATGGGGTGGGCGCCACCCTCGCCCGCAAGGTCAAGCCGGGGGAGAT
GCATGTCATTCCCGCGCCATCGGCCGTTTCGCTGGCGGCCGCCCGCCTTGGCTGGGCGCTGCAGGATATCGAGATTGTCT
CGCTGCATGGCCGGCCGCTCGACCTGATCCGACCGCTGCTGCAGCCCAATGCGCGCATCCTGGCGCTGACGTCGGATGCC
GAAGCGCCTGATGCAATTGCCCGCCTGCTCACCGAACTCGATTTCGGCGCCTCGCGGCTGACGGTACTGGAGGCGCTGGG
CGGGCCAAAGGAGAACCAGCGCTCCGCCCGCGCCGATACCTTCGACCTAGAAAACATCAATCCGCTCAATGTGCTGGCCA
TCGAAATTGATTCGAATCCGCAAGCCCGCGTCCTGCCGCTCACGGTCGGTCTTGCCGATCATCTGTTCGACCATGACGGG
CAGATCACCAAACGCGAAATCCGCGCCATCACCCTGTCGTCACTGGCGCCGAGGCGCGGCGAATTGCTGTGGGACATCGG
CGCCGGCTCGGGCTCCATCGGCATCGAATGGATGCTCGCCCACCCCTCGATGCGCACGATCGCCATCGAAGCCGACCCGA
CCCGCGCCGTCCGCATCCACCGCAACGCCGCCGCCTGTGGCGTTCCCGGCCTTGTCGTGGTGGAAGGCAGCGCACCCAAG
GCGCTGGCCAGGCTGGACACGCCGGACGCGATCTTCATCGGCGGCGGCGGCAGTGATAGCGGTGTGTTGAACGCTGCCAT
CAAGGCGCTGCGTTCCGGCGGCCGGCTCGTCGCCAACGCGGTGACGCTGGAGATGGAAGCCCTGCTTCTCGCGCAGCACG
CAAAGCTTGGTGGTGACATCATCCGGATAAACATTTCGCGTGCCTCGCCGGTCGGTTCGATGCAGGCATGGCGGCCGGCC
ATGCCGGTCACGCAATGGAGCTGGGTGAAGCCATGA

Upstream 100 bases:

>100_bases
GCCGGCCAGCGACAGCGTGACCGAGGTTCGTACCGCCAGCTTGCCAGCCAGTTGCCGGGCTTCCGTGGTGCCGCCGAGGA
TCAGAATGCGGTGGGTCATC

Downstream 100 bases:

>100_bases
TGGTCGCGGGCATCGGCAGCCGCAAAGGCGTGAGCGTTGAAGACGTGCTTGCCGCGGTTGAAACCGCTCTGGAAGCGCAC
GGGCTGGCCATGACGGCGCT

Product: precorrin 6y methylase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPAESSRGAGPKWLTVIGIGEDGLAGLGDEAKQRIAKAEIIFGGKRHLALVASFAKGEPRPWPVPFDAGMADVLALAGRN
VCVLASGDPFFHGVGATLARKVKPGEMHVIPAPSAVSLAAARLGWALQDIEIVSLHGRPLDLIRPLLQPNARILALTSDA
EAPDAIARLLTELDFGASRLTVLEALGGPKENQRSARADTFDLENINPLNVLAIEIDSNPQARVLPLTVGLADHLFDHDG
QITKREIRAITLSSLAPRRGELLWDIGAGSGSIGIEWMLAHPSMRTIAIEADPTRAVRIHRNAAACGVPGLVVVEGSAPK
ALARLDTPDAIFIGGGGSDSGVLNAAIKALRSGGRLVANAVTLEMEALLLAQHAKLGGDIIRINISRASPVGSMQAWRPA
MPVTQWSWVKP

Sequences:

>Translated_411_residues
MPAESSRGAGPKWLTVIGIGEDGLAGLGDEAKQRIAKAEIIFGGKRHLALVASFAKGEPRPWPVPFDAGMADVLALAGRN
VCVLASGDPFFHGVGATLARKVKPGEMHVIPAPSAVSLAAARLGWALQDIEIVSLHGRPLDLIRPLLQPNARILALTSDA
EAPDAIARLLTELDFGASRLTVLEALGGPKENQRSARADTFDLENINPLNVLAIEIDSNPQARVLPLTVGLADHLFDHDG
QITKREIRAITLSSLAPRRGELLWDIGAGSGSIGIEWMLAHPSMRTIAIEADPTRAVRIHRNAAACGVPGLVVVEGSAPK
ALARLDTPDAIFIGGGGSDSGVLNAAIKALRSGGRLVANAVTLEMEALLLAQHAKLGGDIIRINISRASPVGSMQAWRPA
MPVTQWSWVKP
>Mature_410_residues
PAESSRGAGPKWLTVIGIGEDGLAGLGDEAKQRIAKAEIIFGGKRHLALVASFAKGEPRPWPVPFDAGMADVLALAGRNV
CVLASGDPFFHGVGATLARKVKPGEMHVIPAPSAVSLAAARLGWALQDIEIVSLHGRPLDLIRPLLQPNARILALTSDAE
APDAIARLLTELDFGASRLTVLEALGGPKENQRSARADTFDLENINPLNVLAIEIDSNPQARVLPLTVGLADHLFDHDGQ
ITKREIRAITLSSLAPRRGELLWDIGAGSGSIGIEWMLAHPSMRTIAIEADPTRAVRIHRNAAACGVPGLVVVEGSAPKA
LARLDTPDAIFIGGGGSDSGVLNAAIKALRSGGRLVANAVTLEMEALLLAQHAKLGGDIIRINISRASPVGSMQAWRPAM
PVTQWSWVKP

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43274; Mature: 43142

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAESSRGAGPKWLTVIGIGEDGLAGLGDEAKQRIAKAEIIFGGKRHLALVASFAKGEPR
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHEEEEECCCCEEEEEEEHHCCCCC
PWPVPFDAGMADVLALAGRNVCVLASGDPFFHGVGATLARKVKPGEMHVIPAPSAVSLAA
CCCCCCCCCHHHHHHHCCCCEEEEECCCCCEECCCHHHHHCCCCCCEEEEECCCHHHHHH
ARLGWALQDIEIVSLHGRPLDLIRPLLQPNARILALTSDAEAPDAIARLLTELDFGASRL
HHHCCEEECEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHH
TVLEALGGPKENQRSARADTFDLENINPLNVLAIEIDSNPQARVLPLTVGLADHLFDHDG
HHHHHHCCCCCCCCCCCCCEECCCCCCCEEEEEEEECCCCCEEEEEEEECHHHHHHCCCC
QITKREIRAITLSSLAPRRGELLWDIGAGSGSIGIEWMLAHPSMRTIAIEADPTRAVRIH
CEEHHHHEEEEEHHCCCCCCCEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCEEEEEE
RNAAACGVPGLVVVEGSAPKALARLDTPDAIFIGGGGSDSGVLNAAIKALRSGGRLVANA
CCCCCCCCCEEEEEECCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEE
VTLEMEALLLAQHAKLGGDIIRINISRASPVGSMQAWRPAMPVTQWSWVKP
EEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PAESSRGAGPKWLTVIGIGEDGLAGLGDEAKQRIAKAEIIFGGKRHLALVASFAKGEPR
CCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHEEEEECCCCEEEEEEEHHCCCCC
PWPVPFDAGMADVLALAGRNVCVLASGDPFFHGVGATLARKVKPGEMHVIPAPSAVSLAA
CCCCCCCCCHHHHHHHCCCCEEEEECCCCCEECCCHHHHHCCCCCCEEEEECCCHHHHHH
ARLGWALQDIEIVSLHGRPLDLIRPLLQPNARILALTSDAEAPDAIARLLTELDFGASRL
HHHCCEEECEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHH
TVLEALGGPKENQRSARADTFDLENINPLNVLAIEIDSNPQARVLPLTVGLADHLFDHDG
HHHHHHCCCCCCCCCCCCCEECCCCCCCEEEEEEEECCCCCEEEEEEEECHHHHHHCCCC
QITKREIRAITLSSLAPRRGELLWDIGAGSGSIGIEWMLAHPSMRTIAIEADPTRAVRIH
CEEHHHHEEEEEHHCCCCCCCEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCEEEEEE
RNAAACGVPGLVVVEGSAPKALARLDTPDAIFIGGGGSDSGVLNAAIKALRSGGRLVANA
CCCCCCCCCEEEEEECCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEE
VTLEMEALLLAQHAKLGGDIIRINISRASPVGSMQAWRPAMPVTQWSWVKP
EEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]