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The map label for this gene is erg3 [H]

Identifier: 13471168

GI number: 13471168

Start: 892574

End: 893527

Strand: Reverse

Name: erg3 [H]

Synonym: mll1065

Alternate gene names: 13471168

Gene position: 893527-892574 (Counterclockwise)

Preceding gene: 13471169

Following gene: 13471165

Centisome position: 12.7

GC content: 61.74

Gene sequence:

>954_bases
GTGATGGACAGCTATGATTTTCCGCAGGTCACCCAGCTGGCCATTCCGTTCTTCGTCGCCGCCATCCTGATCGAGCTCTG
GCTTGTGCGCACCGGCCGCGCCAAGGGCTCGTTCGAGACGCGCGACACGCTGACCAGCCTGATGATGGGCACAGGCAATG
TCGTCGCCGGGCTGTTGCTTGGCGTCGTCTCCTACTGGGCGCTGCTGTGGCTGTGGCAGTTCCGCGTCTTCAATCTCGGC
CTGTCGGTCTGGGTGTTCCTCGCTGCCTTCCTGCTCGACGATCTGCGCTACTATGTCTACCACCGCATCGCGCACCGGGT
GCGCTGGGTGTGGGCCGAGCACGTCAACCATCACTCCAGCCAGCACTACAATCTGTCGACGGCGCTCAGGCAAAGCTGGA
CGGGTCTGTTCACCTTCATGTTCGTGCTGCAGGCGCCTTTGGTGCTGCTCGGCTTTCACCCGGCGGTGATTGCCTTCACC
TTCGGCTTCAACCTGGTCTGGCAGTTCTGGATCCACACCGAGACTATCGGCAAGATGTGGGGCTGGTTCGAATTCGTCTT
CAACACGCCCTCGCACCACCGCGTCCACCACGCCACCAACCCGCGCTATCTCGACGCCAACTATGCCGGCACGTTGATCA
TCTGGGACCGCATGTTCGGCACATTCGTCGAGGAGTTGGAAGAGGACCGGCCGCGCTACGGCATCGTCAAGAATCTGGGC
ACCTTCAACCCGTTGAAAGTGGCGTTCCACGAATGGATCGGCATGTTCAGCGATGCGTTTGCGCCGGGGCTGATCTTGAG
CGACCGGCTGAACTACCTGATCAAGCCGCCAGGCTGGAGCCATGACGGCTCGCGCGAAACCTCGGAGAGCCTGAAAGCTG
CCTATGTCAGGCGAAATCCGGGTGAGGCTGGCAAGCCGGGACTGCCGACGGCGAATGTCGAGCCGGCGGAATAG

Upstream 100 bases:

>100_bases
ACTTCACCTGGAAGGGCGGCCGCTTCCACTTGGCCAATGCCGGCGATGCGCAGGCCTTGCTGAAGGCTCTTGAAGCACGC
CATGCCGCCAAGGAGGCCGC

Downstream 100 bases:

>100_bases
GGGAATTACTCCGCCGCTTCGGCCGTTTCTGTTGGCGCCGGCAGGCCCAGCCATTGCCGGCAATCGCCCAGCGCGCGCGA
TGTGATGGCGTGCCGTTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MMDSYDFPQVTQLAIPFFVAAILIELWLVRTGRAKGSFETRDTLTSLMMGTGNVVAGLLLGVVSYWALLWLWQFRVFNLG
LSVWVFLAAFLLDDLRYYVYHRIAHRVRWVWAEHVNHHSSQHYNLSTALRQSWTGLFTFMFVLQAPLVLLGFHPAVIAFT
FGFNLVWQFWIHTETIGKMWGWFEFVFNTPSHHRVHHATNPRYLDANYAGTLIIWDRMFGTFVEELEEDRPRYGIVKNLG
TFNPLKVAFHEWIGMFSDAFAPGLILSDRLNYLIKPPGWSHDGSRETSESLKAAYVRRNPGEAGKPGLPTANVEPAE

Sequences:

>Translated_317_residues
MMDSYDFPQVTQLAIPFFVAAILIELWLVRTGRAKGSFETRDTLTSLMMGTGNVVAGLLLGVVSYWALLWLWQFRVFNLG
LSVWVFLAAFLLDDLRYYVYHRIAHRVRWVWAEHVNHHSSQHYNLSTALRQSWTGLFTFMFVLQAPLVLLGFHPAVIAFT
FGFNLVWQFWIHTETIGKMWGWFEFVFNTPSHHRVHHATNPRYLDANYAGTLIIWDRMFGTFVEELEEDRPRYGIVKNLG
TFNPLKVAFHEWIGMFSDAFAPGLILSDRLNYLIKPPGWSHDGSRETSESLKAAYVRRNPGEAGKPGLPTANVEPAE
>Mature_317_residues
MMDSYDFPQVTQLAIPFFVAAILIELWLVRTGRAKGSFETRDTLTSLMMGTGNVVAGLLLGVVSYWALLWLWQFRVFNLG
LSVWVFLAAFLLDDLRYYVYHRIAHRVRWVWAEHVNHHSSQHYNLSTALRQSWTGLFTFMFVLQAPLVLLGFHPAVIAFT
FGFNLVWQFWIHTETIGKMWGWFEFVFNTPSHHRVHHATNPRYLDANYAGTLIIWDRMFGTFVEELEEDRPRYGIVKNLG
TFNPLKVAFHEWIGMFSDAFAPGLILSDRLNYLIKPPGWSHDGSRETSESLKAAYVRRNPGEAGKPGLPTANVEPAE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=286, Percent_Identity=40.5594405594406, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI25144659, Length=278, Percent_Identity=34.5323741007194, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 36543; Mature: 36543

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDSYDFPQVTQLAIPFFVAAILIELWLVRTGRAKGSFETRDTLTSLMMGTGNVVAGLLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
GVVSYWALLWLWQFRVFNLGLSVWVFLAAFLLDDLRYYVYHRIAHRVRWVWAEHVNHHSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QHYNLSTALRQSWTGLFTFMFVLQAPLVLLGFHPAVIAFTFGFNLVWQFWIHTETIGKMW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWFEFVFNTPSHHRVHHATNPRYLDANYAGTLIIWDRMFGTFVEELEEDRPRYGIVKNLG
HHHHHHHCCCCCCEEECCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHCC
TFNPLKVAFHEWIGMFSDAFAPGLILSDRLNYLIKPPGWSHDGSRETSESLKAAYVRRNP
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
GEAGKPGLPTANVEPAE
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMDSYDFPQVTQLAIPFFVAAILIELWLVRTGRAKGSFETRDTLTSLMMGTGNVVAGLLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
GVVSYWALLWLWQFRVFNLGLSVWVFLAAFLLDDLRYYVYHRIAHRVRWVWAEHVNHHSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QHYNLSTALRQSWTGLFTFMFVLQAPLVLLGFHPAVIAFTFGFNLVWQFWIHTETIGKMW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWFEFVFNTPSHHRVHHATNPRYLDANYAGTLIIWDRMFGTFVEELEEDRPRYGIVKNLG
HHHHHHHCCCCCCEEECCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHCC
TFNPLKVAFHEWIGMFSDAFAPGLILSDRLNYLIKPPGWSHDGSRETSESLKAAYVRRNP
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCC
GEAGKPGLPTANVEPAE
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]