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The map label for this gene is ntrY [H]

Identifier: 13470633

GI number: 13470633

Start: 284838

End: 287054

Strand: Direct

Name: ntrY [H]

Synonym: mlr0399

Alternate gene names: 13470633

Gene position: 284838-287054 (Clockwise)

Preceding gene: 13470632

Following gene: 13470634

Centisome position: 4.05

GC content: 63.37

Gene sequence:

>2217_bases
TTGCTGGCGCTGCCCGGCGTGGTGGCCGTCGTCGGCGCGCTGGTCATGGCGGCCATCTCGTTCACCATCCTGGTCGGCGC
GACGCCGATCGCGCCTGACGCCAGGACGACCTGGGCGCTGATCGCGCTCAATGCCGCTTTCGTGCTGTTCCTCATGGCGC
TGGTCGGGCGCGAAGTGCATCGCATCGTCATGGCCCGCCGGCATGGCAAGGCGGCCTCGCGGCTGCATGTGCGCATCGTC
GCCATGTTCGCGCTGGTTGCCGCCATCCCCGCCATCATGGTGGCCATCATCGCCTCGATCACGCTCGATATCGGCCTCGA
CCGCTGGTTCGAGATTCGTACCAAGACGATCGTCAATTCCTCGCTGTCGATCGCCGATGCCTATGTCCAGGAGAACGCCC
GCAATCTGCAGGGCACGACGCTGTCGATGGCCTATGATCTCGACGCGTCGCGCTCGCTATACGGCCTTGATCGCACAGGC
TTTCTCGACCTCCTGAACAAGGAGGCGGTGGGCCGGTCGCTGGCCCATGCGGCGCTGATCAAGCCCGACGGTTCGTTCGT
CATGAGCGCGCAGACCGATGCCGATTTCGCCATGCCGGAACCGCCGGAAGGTTCAGTCAGCAGCGCCACCGACGGCAAGC
CGGTGCTGATAGAGCCGCGCACCCGCAACATCATGGGCGCCATCGTCAAGCTGCGCGAAATCGAGGGCCTCTACCTCTAC
ACCATCCGCCTTGTCGATCCCGAGGTGATCAAGGCGCGGCAGATCGTCAGGTCCAACACCGACGAGTATCGCAATCTCGA
AGACAACAGGCGCACGTCGCAAGTAGCCTTCGCGCTGCCCTATCTGTCGCTGACCCTGATCATCATCTTGTCGGCAATCT
GGACGGGCATCGCGGTCGCCGACCGCCTCGTGCGGCCGATTCGCCAGCTCATTGGCGCTGCCGACGAAGTGGCGACCGGC
AATCTCGACGTCGCGGTTCCGGTTAGATCTTCCGACGGCGATGTCGCCTCGCTTGGCGACACCTTCAACAAGATGCTGCT
GGAGCTCAAATCGCAGCGCAACGAGATCCTGTCGGCGAAGGACCTGATCGACGAGCGGCGGCGCTTCTCCGAAGCCGTGC
TTGCCGGTGTCACCGCCGGCGTCATCGGCGTCGATCCCTACGGCATCGTCACCATCGTCAACCGTTCGGCCGAATCGATG
CTGGCCATCTCCGCCAGTGCCGCACTCGGGCAGAACCTTTCCGCTATTTTGCCGCATGTCGGCCGCGTCTTCGAGATCGG
CCGCCAGTCGGGCAAGCCCGTCTACCGCGAGCAGGTGACGTTTTTCCGCGCCGGCACCGAGCGCACTTTCAACGTGCAGA
TCACCATCGAAGCGGGCGACGACGGCTCGGAAGAGAAATCCTACGTCGTGACCGTCGACGACATCACCGATCTGGTCCAG
GCGCAGCGTTCTTCAGCCTGGGCCGACGTCGCGCGCCGCATCGCCCACGAGATCAAGAACCCGCTGACGCCGATCCAGCT
TTCGGCCGAGCGCATCAAGCGCCGATACGGCAAGGTCATCACCGAGGACCGCGAGGTTTTCGACCAATGCACCGACACCA
TCATCCGGCAGGTCGAGGACATCGGCCGCATGGTCGACGAATTCTCCGCCTTCGCGCGCATGCCCAAGCCCGAGATGAAG
GCCATCGATCTGCGCGAATCGCTGCGCGAGGCATCCTTCCTGGTCGAGGTCAGCCGCGCCGACATCACCTTCGAGCGGAT
TTTCGGCAATGAACCGCTCAAGGGCACATTCGACAGCCGCCTTCTGGCGCAGGCTTTCGGCAATGTGATCAAGAACGCCG
CCGAGGCGATCGACGGACTGGAACAAAAGGACGGTTCGCACGGCATAATCCGGATTCAAGCCGGCCGTCAGAATGGCGCG
ATTCGTATCGACGTCATCGACAATGGCAAAGGCCTGCCGCGCGAGAATCGCCAACGGCTGCTCGAGCCCTATATGACCAC
GCGCGAGAAAGGCACCGGGCTTGGTCTCGCTATCGTCAAGAAGATCGTGGAGGACCATGGCGGCAGGCTGGAACTTCATG
ATGCGCCTGCGGACTTCCACGGCGGCCGCGGGGCGATGATCAGCATCATCCTGCCGCTGGCGGCCGTCACGCCGTTGCGC
GGCGAAGGCAAGACGGAACACGAAAGAGAAACTGAAAAGGTCGGTAATGGCGTCTGA

Upstream 100 bases:

>100_bases
CGGACGCAATCATTGGCTCCCAGACGGCGACATGGCTCCGCAGGCACCTGTACTCAATCAACCGCTATTCAGCGAACCCG
GCGCGCGCGACGGGCGCCGC

Downstream 100 bases:

>100_bases
TATTCTCATCGTCGATGACGAGGAAGACATCCGCGAGCTCGTCGCAGGCATATTGAGCGACGAAGGTCACGAAACCCGCA
CGGCATTCGACGCCGACAGC

Product: nitrogen regulation protein ntrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 738; Mature: 738

Protein sequence:

>738_residues
MLALPGVVAVVGALVMAAISFTILVGATPIAPDARTTWALIALNAAFVLFLMALVGREVHRIVMARRHGKAASRLHVRIV
AMFALVAAIPAIMVAIIASITLDIGLDRWFEIRTKTIVNSSLSIADAYVQENARNLQGTTLSMAYDLDASRSLYGLDRTG
FLDLLNKEAVGRSLAHAALIKPDGSFVMSAQTDADFAMPEPPEGSVSSATDGKPVLIEPRTRNIMGAIVKLREIEGLYLY
TIRLVDPEVIKARQIVRSNTDEYRNLEDNRRTSQVAFALPYLSLTLIIILSAIWTGIAVADRLVRPIRQLIGAADEVATG
NLDVAVPVRSSDGDVASLGDTFNKMLLELKSQRNEILSAKDLIDERRRFSEAVLAGVTAGVIGVDPYGIVTIVNRSAESM
LAISASAALGQNLSAILPHVGRVFEIGRQSGKPVYREQVTFFRAGTERTFNVQITIEAGDDGSEEKSYVVTVDDITDLVQ
AQRSSAWADVARRIAHEIKNPLTPIQLSAERIKRRYGKVITEDREVFDQCTDTIIRQVEDIGRMVDEFSAFARMPKPEMK
AIDLRESLREASFLVEVSRADITFERIFGNEPLKGTFDSRLLAQAFGNVIKNAAEAIDGLEQKDGSHGIIRIQAGRQNGA
IRIDVIDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIVEDHGGRLELHDAPADFHGGRGAMISIILPLAAVTPLR
GEGKTEHERETEKVGNGV

Sequences:

>Translated_738_residues
MLALPGVVAVVGALVMAAISFTILVGATPIAPDARTTWALIALNAAFVLFLMALVGREVHRIVMARRHGKAASRLHVRIV
AMFALVAAIPAIMVAIIASITLDIGLDRWFEIRTKTIVNSSLSIADAYVQENARNLQGTTLSMAYDLDASRSLYGLDRTG
FLDLLNKEAVGRSLAHAALIKPDGSFVMSAQTDADFAMPEPPEGSVSSATDGKPVLIEPRTRNIMGAIVKLREIEGLYLY
TIRLVDPEVIKARQIVRSNTDEYRNLEDNRRTSQVAFALPYLSLTLIIILSAIWTGIAVADRLVRPIRQLIGAADEVATG
NLDVAVPVRSSDGDVASLGDTFNKMLLELKSQRNEILSAKDLIDERRRFSEAVLAGVTAGVIGVDPYGIVTIVNRSAESM
LAISASAALGQNLSAILPHVGRVFEIGRQSGKPVYREQVTFFRAGTERTFNVQITIEAGDDGSEEKSYVVTVDDITDLVQ
AQRSSAWADVARRIAHEIKNPLTPIQLSAERIKRRYGKVITEDREVFDQCTDTIIRQVEDIGRMVDEFSAFARMPKPEMK
AIDLRESLREASFLVEVSRADITFERIFGNEPLKGTFDSRLLAQAFGNVIKNAAEAIDGLEQKDGSHGIIRIQAGRQNGA
IRIDVIDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIVEDHGGRLELHDAPADFHGGRGAMISIILPLAAVTPLR
GEGKTEHERETEKVGNGV
>Mature_738_residues
MLALPGVVAVVGALVMAAISFTILVGATPIAPDARTTWALIALNAAFVLFLMALVGREVHRIVMARRHGKAASRLHVRIV
AMFALVAAIPAIMVAIIASITLDIGLDRWFEIRTKTIVNSSLSIADAYVQENARNLQGTTLSMAYDLDASRSLYGLDRTG
FLDLLNKEAVGRSLAHAALIKPDGSFVMSAQTDADFAMPEPPEGSVSSATDGKPVLIEPRTRNIMGAIVKLREIEGLYLY
TIRLVDPEVIKARQIVRSNTDEYRNLEDNRRTSQVAFALPYLSLTLIIILSAIWTGIAVADRLVRPIRQLIGAADEVATG
NLDVAVPVRSSDGDVASLGDTFNKMLLELKSQRNEILSAKDLIDERRRFSEAVLAGVTAGVIGVDPYGIVTIVNRSAESM
LAISASAALGQNLSAILPHVGRVFEIGRQSGKPVYREQVTFFRAGTERTFNVQITIEAGDDGSEEKSYVVTVDDITDLVQ
AQRSSAWADVARRIAHEIKNPLTPIQLSAERIKRRYGKVITEDREVFDQCTDTIIRQVEDIGRMVDEFSAFARMPKPEMK
AIDLRESLREASFLVEVSRADITFERIFGNEPLKGTFDSRLLAQAFGNVIKNAAEAIDGLEQKDGSHGIIRIQAGRQNGA
IRIDVIDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIVEDHGGRLELHDAPADFHGGRGAMISIILPLAAVTPLR
GEGKTEHERETEKVGNGV

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=363, Percent_Identity=24.7933884297521, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=28.6324786324786, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790300, Length=345, Percent_Identity=24.9275362318841, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=207, Percent_Identity=28.9855072463768, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=29.3859649122807, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80534; Mature: 80534

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALPGVVAVVGALVMAAISFTILVGATPIAPDARTTWALIALNAAFVLFLMALVGREVH
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RIVMARRHGKAASRLHVRIVAMFALVAAIPAIMVAIIASITLDIGLDRWFEIRTKTIVNS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
SLSIADAYVQENARNLQGTTLSMAYDLDASRSLYGLDRTGFLDLLNKEAVGRSLAHAALI
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEE
KPDGSFVMSAQTDADFAMPEPPEGSVSSATDGKPVLIEPRTRNIMGAIVKLREIEGLYLY
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEE
TIRLVDPEVIKARQIVRSNTDEYRNLEDNRRTSQVAFALPYLSLTLIIILSAIWTGIAVA
EEEECCHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLVRPIRQLIGAADEVATGNLDVAVPVRSSDGDVASLGDTFNKMLLELKSQRNEILSAK
HHHHHHHHHHHCCCHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLIDERRRFSEAVLAGVTAGVIGVDPYGIVTIVNRSAESMLAISASAALGQNLSAILPHV
HHHHHHHHHHHHHHHHHHHCEEECCCCEEEEEECCCCHHHHHEEHHHHHCCCHHHHHHHH
GRVFEIGRQSGKPVYREQVTFFRAGTERTFNVQITIEAGDDGSEEKSYVVTVDDITDLVQ
HHHHHHHHCCCCCHHHHHHHHEECCCCEEEEEEEEEEECCCCCCCCEEEEEHHHHHHHHH
AQRSSAWADVARRIAHEIKNPLTPIQLSAERIKRRYGKVITEDREVFDQCTDTIIRQVED
HHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IGRMVDEFSAFARMPKPEMKAIDLRESLREASFLVEVSRADITFERIFGNEPLKGTFDSR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEHHHHHCCCCCCCCHHHH
LLAQAFGNVIKNAAEAIDGLEQKDGSHGIIRIQAGRQNGAIRIDVIDNGKGLPRENRQRL
HHHHHHHHHHHHHHHHHHCHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHH
LEPYMTTREKGTGLGLAIVKKIVEDHGGRLELHDAPADFHGGRGAMISIILPLAAVTPLR
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
GEGKTEHERETEKVGNGV
CCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MLALPGVVAVVGALVMAAISFTILVGATPIAPDARTTWALIALNAAFVLFLMALVGREVH
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RIVMARRHGKAASRLHVRIVAMFALVAAIPAIMVAIIASITLDIGLDRWFEIRTKTIVNS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
SLSIADAYVQENARNLQGTTLSMAYDLDASRSLYGLDRTGFLDLLNKEAVGRSLAHAALI
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEE
KPDGSFVMSAQTDADFAMPEPPEGSVSSATDGKPVLIEPRTRNIMGAIVKLREIEGLYLY
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEE
TIRLVDPEVIKARQIVRSNTDEYRNLEDNRRTSQVAFALPYLSLTLIIILSAIWTGIAVA
EEEECCHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLVRPIRQLIGAADEVATGNLDVAVPVRSSDGDVASLGDTFNKMLLELKSQRNEILSAK
HHHHHHHHHHHCCCHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLIDERRRFSEAVLAGVTAGVIGVDPYGIVTIVNRSAESMLAISASAALGQNLSAILPHV
HHHHHHHHHHHHHHHHHHHCEEECCCCEEEEEECCCCHHHHHEEHHHHHCCCHHHHHHHH
GRVFEIGRQSGKPVYREQVTFFRAGTERTFNVQITIEAGDDGSEEKSYVVTVDDITDLVQ
HHHHHHHHCCCCCHHHHHHHHEECCCCEEEEEEEEEEECCCCCCCCEEEEEHHHHHHHHH
AQRSSAWADVARRIAHEIKNPLTPIQLSAERIKRRYGKVITEDREVFDQCTDTIIRQVED
HHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IGRMVDEFSAFARMPKPEMKAIDLRESLREASFLVEVSRADITFERIFGNEPLKGTFDSR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEHHHHHCCCCCCCCHHHH
LLAQAFGNVIKNAAEAIDGLEQKDGSHGIIRIQAGRQNGAIRIDVIDNGKGLPRENRQRL
HHHHHHHHHHHHHHHHHHCHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHH
LEPYMTTREKGTGLGLAIVKKIVEDHGGRLELHDAPADFHGGRGAMISIILPLAAVTPLR
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCC
GEGKTEHERETEKVGNGV
CCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]