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The map label for this gene is frdC

Identifier: 15602064

GI number: 15602064

Start: 222412

End: 222810

Strand: Reverse

Name: frdC

Synonym: PM0199

Alternate gene names: 15602064

Gene position: 222810-222412 (Counterclockwise)

Preceding gene: 229282647

Following gene: 15602063

Centisome position: 9.87

GC content: 34.34

Gene sequence:

>399_bases
ATGACAGCAACAACCAGTAAACGCAAAAAATACGTGCGTGAAATGAAACCAACTTGGTGGAAAAAGTTAGATTTTTACAA
ACTTTATATTGCGCGTGAAGCCACTGCAATTCCAACACTTTGGTTCTGTTTAGTCTTACTTTATGGAGTGATTAGCCTAG
GTAGTTTAGACAGTTTTGGCAATTTCATTTCATTCTTGAAAAACCCGATTGTGATTATTTTAAATATCATCACACTCGGT
GCAATGTTATTAAATACGGTGACTTACTATGTAATGACACCTAAAGTATTAAATATCATTGTTAAGAATGAACGAATTAA
TCCTAACATCATTACGATGGCATTGTGGGCGGTAACAGCCTTTATCAGCCTCGTCATTTTAGTCTTTATGTATGTATAA

Upstream 100 bases:

>100_bases
AAACACGTCGATCCAGCTTCCGCGGTAAACCAAGGTAAAGTCGAAAGTGCAAAAGACTTTGTAATTGCAATGCTTAAACC
GCAAAAGTAAGGAGTGTAAA

Downstream 100 bases:

>100_bases
GCGAGGAGAGAAAGATGAAAGATACACCAAAACGTTCTAATGAACCTGTTGTATGGTTATTGTTTGGCGCAGGAACAACT
GTCAGTGCCATGTTCTATCC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MTATTSKRKKYVREMKPTWWKKLDFYKLYIAREATAIPTLWFCLVLLYGVISLGSLDSFGNFISFLKNPIVIILNIITLG
AMLLNTVTYYVMTPKVLNIIVKNERINPNIITMALWAVTAFISLVILVFMYV

Sequences:

>Translated_132_residues
MTATTSKRKKYVREMKPTWWKKLDFYKLYIAREATAIPTLWFCLVLLYGVISLGSLDSFGNFISFLKNPIVIILNIITLG
AMLLNTVTYYVMTPKVLNIIVKNERINPNIITMALWAVTAFISLVILVFMYV
>Mature_131_residues
TATTSKRKKYVREMKPTWWKKLDFYKLYIAREATAIPTLWFCLVLLYGVISLGSLDSFGNFISFLKNPIVIILNIITLGA
MLLNTVTYYVMTPKVLNIIVKNERINPNIITMALWAVTAFISLVILVFMYV

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family

Homologues:

Organism=Escherichia coli, GI1790595, Length=124, Percent_Identity=48.3870967741936, Blast_Score=132, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDC_PASMU (Q9CP58)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245136.1
- ProteinModelPortal:   Q9CP58
- SMR:   Q9CP58
- GeneID:   1243546
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0199
- NMPDR:   fig|272843.1.peg.199
- HOGENOM:   HBG554089
- OMA:   KMGPEPV
- ProtClustDB:   PRK04987
- BioCyc:   PMUL272843:PM0199-MONOMER
- HAMAP:   MF_00708
- InterPro:   IPR003510
- ProDom:   PD015900

Pfam domain/function: PF02300 Fumarate_red_C

EC number: 1.3.99.1

Molecular weight: Translated: 15205; Mature: 15073

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x403a7fc4)-; HASH(0xb0c9688)-; HASH(0xc44c940)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATTSKRKKYVREMKPTWWKKLDFYKLYIAREATAIPTLWFCLVLLYGVISLGSLDSFG
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NFISFLKNPIVIILNIITLGAMLLNTVTYYVMTPKVLNIIVKNERINPNIITMALWAVTA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
FISLVILVFMYV
HHHHHHHHHHHH
>Mature Secondary Structure 
TATTSKRKKYVREMKPTWWKKLDFYKLYIAREATAIPTLWFCLVLLYGVISLGSLDSFG
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NFISFLKNPIVIILNIITLGAMLLNTVTYYVMTPKVLNIIVKNERINPNIITMALWAVTA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
FISLVILVFMYV
HHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100