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The map label for this gene is frdD

Identifier: 15602063

GI number: 15602063

Start: 222047

End: 222397

Strand: Reverse

Name: frdD

Synonym: PM0198

Alternate gene names: 15602063

Gene position: 222397-222047 (Counterclockwise)

Preceding gene: 15602064

Following gene: 15602060

Centisome position: 9.85

GC content: 37.04

Gene sequence:

>351_bases
ATGAAAGATACACCAAAACGTTCTAATGAACCTGTTGTATGGTTATTGTTTGGCGCAGGAACAACTGTCAGTGCCATGTT
CTATCCTGTGTTAGTATTAATTCTTGGCTTCTTGCTACCATTTGGTTTAATTGATCCCAAAAATATCATTGAACTTATAG
GCTTCTTACACAGCCCATTAGGTAAATTACTGTTACTTGTGTTATTAATTTTCCCAATGTGGGGAGCGATGCACCGTATC
CATCATGGTATGCATGACTTCAAAATCCACATTCCAGCAAGTGGTGTCATTTTCTATGGTTTATCTGTGCTTTATACGGT
ATTAGTTTGCTTCGCTGTATTTAGCTTATAA

Upstream 100 bases:

>100_bases
GAATTAATCCTAACATCATTACGATGGCATTGTGGGCGGTAACAGCCTTTATCAGCCTCGTCATTTTAGTCTTTATGTAT
GTATAAGCGAGGAGAGAAAG

Downstream 100 bases:

>100_bases
TTCATCCCTAAATCACAAAAGGCGGATATGTTATCCGCCTTTCTTATATTACATTCCCTCTCCCCTTTCCTCATTCTTAG
CAAGCAAGTTTTCTTCCTTC

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKDTPKRSNEPVVWLLFGAGTTVSAMFYPVLVLILGFLLPFGLIDPKNIIELIGFLHSPLGKLLLLVLLIFPMWGAMHRI
HHGMHDFKIHIPASGVIFYGLSVLYTVLVCFAVFSL

Sequences:

>Translated_116_residues
MKDTPKRSNEPVVWLLFGAGTTVSAMFYPVLVLILGFLLPFGLIDPKNIIELIGFLHSPLGKLLLLVLLIFPMWGAMHRI
HHGMHDFKIHIPASGVIFYGLSVLYTVLVCFAVFSL
>Mature_116_residues
MKDTPKRSNEPVVWLLFGAGTTVSAMFYPVLVLILGFLLPFGLIDPKNIIELIGFLHSPLGKLLLLVLLIFPMWGAMHRI
HHGMHDFKIHIPASGVIFYGLSVLYTVLVCFAVFSL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family

Homologues:

Organism=Escherichia coli, GI1790594, Length=118, Percent_Identity=42.3728813559322, Blast_Score=105, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDD_PASMU (Q9CP59)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245135.1
- ProteinModelPortal:   Q9CP59
- SMR:   Q9CP59
- GeneID:   1243545
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0198
- NMPDR:   fig|272843.1.peg.198
- HOGENOM:   HBG297136
- OMA:   HRIHHGM
- ProtClustDB:   PRK05470
- BioCyc:   PMUL272843:PM0198-MONOMER
- HAMAP:   MF_00709
- InterPro:   IPR003418
- ProDom:   PD015693

Pfam domain/function: PF02313 Fumarate_red_D

EC number: 1.3.99.1

Molecular weight: Translated: 12947; Mature: 12947

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbb51f54)-; HASH(0xbb12690)-; HASH(0xc3913ac)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDTPKRSNEPVVWLLFGAGTTVSAMFYPVLVLILGFLLPFGLIDPKNIIELIGFLHSPL
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCH
GKLLLLVLLIFPMWGAMHRIHHGMHDFKIHIPASGVIFYGLSVLYTVLVCFAVFSL
HHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MKDTPKRSNEPVVWLLFGAGTTVSAMFYPVLVLILGFLLPFGLIDPKNIIELIGFLHSPL
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCH
GKLLLLVLLIFPMWGAMHRIHHGMHDFKIHIPASGVIFYGLSVLYTVLVCFAVFSL
HHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100