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The map label for this gene is dhaL

Identifier: 30023984

GI number: 30023984

Start: 245692

End: 246690

Strand: Direct

Name: dhaL

Synonym: L45677

Alternate gene names: 30023984

Gene position: 245692-246690 (Clockwise)

Preceding gene: 30023982

Following gene: 15672231

Centisome position: 10.39

GC content: 37.94

Gene sequence:

>999_bases
ATGAGTGATGAAAAAATTATTAATCAACCACAAGATGTGGTCTCAGAAATGTTAGACGGATTAACCTATGCTTACGGGGA
TTTGATTGAAAAAGTTCCAGATTTTGAAATTATTCAACGTAAAAGTCCTAAAAGTGGAAAAGTTGCCTTAGTATCAGGCG
GGGGTTCTGGACACAAACCGGCTCATGCTGGCTTTGTCGGGGAAGGAATGCTGTCAGCAGCTGTTTGTGGAGCTATTTTC
ACATCACCAACGCCTGATCAAATTTATGAGGCAATCAAATCTGCTGACGAAGGAGCTGGAGTACTCTTAATTATCAAAAA
TTATTTAGGCGATGTGATGAATTTTGAAATGGCACGAGAAATGGCTGAGATGGAAGAGATTAAGGTTGAGCAAATTATTG
TTGACGATGATATCGCCGTTGAAAATTCGCTCTATACTCAAGGAAGACGAGGAGTTGCTGGAACAGTCCTTGTTCATAAA
ATATTAGGCGCAGCTGCCCATCAAGAGGCTTCTTTAGATGAAATCAAAGATTTGGCTGATAAGGTCGTCAAGAATATCAA
GACTATTGGCTTAGCTTTGTCAGCCGCAACAGTTCCAGAAGTTGGAAAACCTGGTTTTGTTCTTGATGATAATGAAATTG
AATATGGCGTAGGAATTCATAGTGAACCCGGATACCGTCGGGAAAAAATGAAAACTTCTTATGAGCTAGCAACAGAACTG
GTTGGAAAGTTGAAAGAAGAATTCAAATTTGAAGCTGGTCAAAAATATGGAATTCTTGTAAATGGTATGGGAGCGACGCC
ACTAATGGAGCAATTCATTTTTATGAATGATGTTGCAAAATTACTGACAGAAGAAAATATTGAAATTCTTTTTAAAAAAG
TTGGGAATTATATGACTTCAATTGATATGGCAGGCTTGTCACTTACAATGATTAAGTTGGAAGATGACCAATGGCTCAAA
AATCTTAATGAAGACGTGAAAACTATTTCTTGGGGATAA

Upstream 100 bases:

>100_bases
TTTTCATATTTAAAAAGAAAGCGGACACATTTTGCGATTTGTCCCTTATTTTTATGGACTTTATATTTTATACTAAGTAT
AACATAAGAAACTCAGGAGG

Downstream 100 bases:

>100_bases
GGAGAGAGAATGTTAACAATAGATACAACCATTGAATGGTTAGGAAAATTCAACGAAAAAATACAAGAAAATAAAGCTTA
TCTAAGCGAACTAGACGGAC

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSDEKIINQPQDVVSEMLDGLTYAYGDLIEKVPDFEIIQRKSPKSGKVALVSGGGSGHKPAHAGFVGEGMLSAAVCGAIF
TSPTPDQIYEAIKSADEGAGVLLIIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHK
ILGAAAHQEASLDEIKDLADKVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHSEPGYRREKMKTSYELATEL
VGKLKEEFKFEAGQKYGILVNGMGATPLMEQFIFMNDVAKLLTEENIEILFKKVGNYMTSIDMAGLSLTMIKLEDDQWLK
NLNEDVKTISWG

Sequences:

>Translated_332_residues
MSDEKIINQPQDVVSEMLDGLTYAYGDLIEKVPDFEIIQRKSPKSGKVALVSGGGSGHKPAHAGFVGEGMLSAAVCGAIF
TSPTPDQIYEAIKSADEGAGVLLIIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHK
ILGAAAHQEASLDEIKDLADKVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHSEPGYRREKMKTSYELATEL
VGKLKEEFKFEAGQKYGILVNGMGATPLMEQFIFMNDVAKLLTEENIEILFKKVGNYMTSIDMAGLSLTMIKLEDDQWLK
NLNEDVKTISWG
>Mature_331_residues
SDEKIINQPQDVVSEMLDGLTYAYGDLIEKVPDFEIIQRKSPKSGKVALVSGGGSGHKPAHAGFVGEGMLSAAVCGAIFT
SPTPDQIYEAIKSADEGAGVLLIIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHKI
LGAAAHQEASLDEIKDLADKVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHSEPGYRREKMKTSYELATELV
GKLKEEFKFEAGQKYGILVNGMGATPLMEQFIFMNDVAKLLTEENIEILFKKVGNYMTSIDMAGLSLTMIKLEDDQWLKN
LNEDVKTISWG

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain

Homologues:

Organism=Homo sapiens, GI20149621, Length=346, Percent_Identity=36.4161849710983, Blast_Score=218, Evalue=8e-57,
Organism=Escherichia coli, GI87081857, Length=355, Percent_Identity=42.8169014084507, Blast_Score=278, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17565018, Length=329, Percent_Identity=32.5227963525836, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321055, Length=319, Percent_Identity=39.4984326018809, Blast_Score=186, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323570, Length=337, Percent_Identity=37.6854599406528, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHAK_LACLA (Q9CIV8)

Other databases:

- EMBL:   AE005176
- PIR:   H86655
- RefSeq:   NP_266404.2
- PDB:   3CT4
- PDBsum:   3CT4
- ProteinModelPortal:   Q9CIV8
- SMR:   Q9CIV8
- GeneID:   1113858
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L45677
- NMPDR:   fig|272623.1.peg.256
- HOGENOM:   HBG473357
- OMA:   TSLEMQG
- ProtClustDB:   PRK14481
- BioCyc:   LLAC272623:L45677-MONOMER
- InterPro:   IPR004006
- InterPro:   IPR012736
- TIGRFAMs:   TIGR02363

Pfam domain/function: PF02733 Dak1

EC number: 2.7.1.29

Molecular weight: Translated: 36243; Mature: 36112

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS51481 DHAK

Important sites: ACT_SITE 220-220 BINDING 106-106 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEKIINQPQDVVSEMLDGLTYAYGDLIEKVPDFEIIQRKSPKSGKVALVSGGGSGHKP
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCC
AHAGFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLLIIKNYLGDVMNFEMARE
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
MAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHKILGAAAHQEASLDEIKDLAD
HHHHHHHHHHHEEECCCHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHSEPGYRREKMKTSYELATEL
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHH
VGKLKEEFKFEAGQKYGILVNGMGATPLMEQFIFMNDVAKLLTEENIEILFKKVGNYMTS
HHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDMAGLSLTMIKLEDDQWLKNLNEDVKTISWG
HHHCCCEEEEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDEKIINQPQDVVSEMLDGLTYAYGDLIEKVPDFEIIQRKSPKSGKVALVSGGGSGHKP
CCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCC
AHAGFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLLIIKNYLGDVMNFEMARE
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
MAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHKILGAAAHQEASLDEIKDLAD
HHHHHHHHHHHEEECCCHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHSEPGYRREKMKTSYELATEL
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHH
VGKLKEEFKFEAGQKYGILVNGMGATPLMEQFIFMNDVAKLLTEENIEILFKKVGNYMTS
HHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDMAGLSLTMIKLEDDQWLKNLNEDVKTISWG
HHHCCCEEEEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471