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The map label for this gene is dhaM

Identifier: 15672231

GI number: 15672231

Start: 246700

End: 247278

Strand: Direct

Name: dhaM

Synonym: L46694

Alternate gene names: 15672231

Gene position: 246700-247278 (Clockwise)

Preceding gene: 30023984

Following gene: 15672232

Centisome position: 10.43

GC content: 37.31

Gene sequence:

>579_bases
ATGTTAACAATAGATACAACCATTGAATGGTTAGGAAAATTCAACGAAAAAATACAAGAAAATAAAGCTTATCTAAGCGA
ACTAGACGGACCTATTGGTGACGGGGATCATGGTGCAAATATGGCTCGTGGGATGTCTGAAACAATGAAAGCATTGGAAG
TTTCAAACTTTGGAAATGTCTCAGAAATCTTTAAAAAAGTGGCTATGACCCTAATGTCAAAAGTAGGAGGAGCTTCTGGT
CCTTTGTATGGTTCAGCCTTTCTAGCCATGAGTAAGACTGCCATAGAAACTTTGGATACAAGTGAATTAATTTATGCTGG
ACTAGAAGCTATTCAAAAAAGAGGAAAAGCTCAAGTCGGTGAAAAAACGATGGTTGATATCTGGTCAGCATTTTTAAATG
ACTTACAAACTGATTCAGCTTCCAAAGATAATTTAGAAAAAGTTGTTAAAGCAAGTGCAGGACTTTTAGCTACAAAAGGA
CGAGCTTCTTATCTTGGGGAACGCTCAATTGGGCACATTGACCCTGGAACACAATCAAGTGCTTATTTATTTGAAACACT
TTTGGAGGTAGTAGCATGA

Upstream 100 bases:

>100_bases
GGCAGGCTTGTCACTTACAATGATTAAGTTGGAAGATGACCAATGGCTCAAAAATCTTAATGAAGACGTGAAAACTATTT
CTTGGGGATAAGGAGAGAGA

Downstream 100 bases:

>100_bases
CTTATGGAATTGTAATCGTTTCTCATTCCCCTGAGATTGCCTCAGGACTAAAAAAATTAATTCGTGAAGTCGCTAAAAAT
ATTTCGCTAACCGCTATAGG

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLTIDTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEVSNFGNVSEIFKKVAMTLMSKVGGASG
PLYGSAFLAMSKTAIETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLNDLQTDSASKDNLEKVVKASAGLLATKG
RASYLGERSIGHIDPGTQSSAYLFETLLEVVA

Sequences:

>Translated_192_residues
MLTIDTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEVSNFGNVSEIFKKVAMTLMSKVGGASG
PLYGSAFLAMSKTAIETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLNDLQTDSASKDNLEKVVKASAGLLATKG
RASYLGERSIGHIDPGTQSSAYLFETLLEVVA
>Mature_192_residues
MLTIDTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEVSNFGNVSEIFKKVAMTLMSKVGGASG
PLYGSAFLAMSKTAIETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLNDLQTDSASKDNLEKVVKASAGLLATKG
RASYLGERSIGHIDPGTQSSAYLFETLLEVVA

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain

Homologues:

Organism=Escherichia coli, GI1787449, Length=198, Percent_Identity=37.8787878787879, Blast_Score=126, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17565018, Length=175, Percent_Identity=30.2857142857143, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323570, Length=190, Percent_Identity=28.4210526315789, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHAL_LACLA (Q9CIV7)

Other databases:

- EMBL:   AE005176
- PIR:   A86656
- RefSeq:   NP_266405.1
- PDB:   3CR3
- PDBsum:   3CR3
- ProteinModelPortal:   Q9CIV7
- SMR:   Q9CIV7
- GeneID:   1113859
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L46694
- NMPDR:   fig|272623.1.peg.257
- HOGENOM:   HBG579729
- OMA:   FETRITK
- ProtClustDB:   CLSK697108
- BioCyc:   LLAC272623:L46694-MONOMER
- InterPro:   IPR004007
- InterPro:   IPR012737
- TIGRFAMs:   TIGR02365

Pfam domain/function: PF02734 Dak2; SSF101473 Dak2

EC number: 2.7.1.29

Molecular weight: Translated: 20579; Mature: 20579

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS51480 DHAL

Important sites: BINDING 115-115 BINDING 161-161

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIDTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEVSNFGNV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
SEIFKKVAMTLMSKVGGASGPLYGSAFLAMSKTAIETLDTSELIYAGLEAIQKRGKAQVG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHCC
EKTMVDIWSAFLNDLQTDSASKDNLEKVVKASAGLLATKGRASYLGERSIGHIDPGTQSS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHCCCHHHHHCCCCCCCCCCCCCCH
AYLFETLLEVVA
HHHHHHHHHHHC
>Mature Secondary Structure
MLTIDTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEVSNFGNV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
SEIFKKVAMTLMSKVGGASGPLYGSAFLAMSKTAIETLDTSELIYAGLEAIQKRGKAQVG
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHCC
EKTMVDIWSAFLNDLQTDSASKDNLEKVVKASAGLLATKGRASYLGERSIGHIDPGTQSS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHCCCHHHHHCCCCCCCCCCCCCCH
AYLFETLLEVVA
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471