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The map label for this gene is ysiA

Identifier: 15673796

GI number: 15673796

Start: 1881457

End: 1882806

Strand: Reverse

Name: ysiA

Synonym: L64811

Alternate gene names: 15673796

Gene position: 1882806-1881457 (Counterclockwise)

Preceding gene: 15673797

Following gene: 15673795

Centisome position: 79.59

GC content: 36.37

Gene sequence:

>1350_bases
ATGTCAAACCCTGATCCCGAGAGTGTATCGATACTCTTGCAGATTCTTTTACTTATTTTTTTAACAGCTTTAAATGCCTT
CTTTTCAGCCAGTGAGATGGCCATGGTCAGTCTCAGCCGGACGAAAGTAGAACAAAAGGCTAGCGAAGGTGATAAGAAAT
ATATCAACCTTGTTAATATCCTTAATCAACCAAGTAATTTCCTCTCAACGATTCAAATTGGGATTACTTTGATTAATATT
TTAGCGGGGGCTAGTTTGGCCGAAGCCTTATCTTCACGTTTAGCTCCACTGTTAGGTGGAACAGCTCTAGCTAAAACTTT
GGCTCAAATTATTGTTTTAGCTGTCTTAACCTATGTCTCTCTCGTATTTGGTGAACTTTATCCGAAGCGAATTGCCCAAA
ACCTTAAAGAAAAACTGGCCCTAAGAGTCGCACCACCTATCCAATTTTTGGGAAAAGTGATGAAACCTTTCGTTTGGTTC
TTGGCAAGTTCAACAAATTTCTTAAGCCGATTGACTCCAATGAAATTTGATGATTTGGATGAAGGGATGACTCGAGATGA
GATTGAGTATTTACTCAATACAAATGATGAAGCACTTGACGCTAATGAGCGTGAAATGATTACTGGGGTGTTCAGCTTAG
ACGAGTTGGTTGCGCGTGAAATCATGGTTCCAAGAACGGATGCTTTCATGATTGATATTAATGATGATTCACGTGAAAAT
ATTACCGCTATTCTAAGTGAAACTTATTCACGGGTACCAGTTTATGATGATGATAAAGATAATATTCTGGGAATTTTACA
TGTGAAAAAACTTTTAAGATATTCTTTTGACCATGGTTTTGATGATATTGACTTACGAGAAATTCTTCAAGAACCTTTGT
TTGTTCCTGAAACAATCTTTGTTGATGACTTAATGCGTCAAATGCGTAAAACTCAGAATCAAATGGCTGTATTATTAAAC
GAATATGGTGGTGTTGAAGGCGTAGTTACCTTAGAAGATTTACTAGAAGAAATCGTTGGTGAAATTGATGACGAAACCGA
TATTGCTGAAGAAGAAGTCTTCAAAATCGGTGAAAATCTCTATGTTGTCCAAGGGAAAATGACTTTGAATGACTTCAATG
AAGAATTTGATACACATCTTGAAAGCAATGACGTTGATACAATTGCAGGTTATTTCTTAGCGACAACTGGTAAAATTCCA
GCTAAAGGACAACAAATTGTCTGCAAAGTAGATAATGATGAAGATCATTTTTCACTGACAAGTTTAGAAGTCTCTGGAAA
ACGTGTGGTTAAACTTCGTGTTGAATTTGATGTCGAACCAGAAGAAACAGAAATTAAAAAAAATTACTGA

Upstream 100 bases:

>100_bases
AATTCTATCTAAATTGTTAACTCTCATTTTCAGTAAATTTGAGTTGGCAAAGTTTTGAGTGTTAAAATAAACACTATAAT
ATTTTTCTCAAGGAGCACTA

Downstream 100 bases:

>100_bases
CAGAAATTCTGTCAGTTTTTTTATAGAATAAAACTGATAATTATTTAGATAAGCCCTTACATCTAGGTACTGACAAGAAA
TAATTTACTAAAAATTTTTA

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSNPDPESVSILLQILLLIFLTALNAFFSASEMAMVSLSRTKVEQKASEGDKKYINLVNILNQPSNFLSTIQIGITLINI
LAGASLAEALSSRLAPLLGGTALAKTLAQIIVLAVLTYVSLVFGELYPKRIAQNLKEKLALRVAPPIQFLGKVMKPFVWF
LASSTNFLSRLTPMKFDDLDEGMTRDEIEYLLNTNDEALDANEREMITGVFSLDELVAREIMVPRTDAFMIDINDDSREN
ITAILSETYSRVPVYDDDKDNILGILHVKKLLRYSFDHGFDDIDLREILQEPLFVPETIFVDDLMRQMRKTQNQMAVLLN
EYGGVEGVVTLEDLLEEIVGEIDDETDIAEEEVFKIGENLYVVQGKMTLNDFNEEFDTHLESNDVDTIAGYFLATTGKIP
AKGQQIVCKVDNDEDHFSLTSLEVSGKRVVKLRVEFDVEPEETEIKKNY

Sequences:

>Translated_449_residues
MSNPDPESVSILLQILLLIFLTALNAFFSASEMAMVSLSRTKVEQKASEGDKKYINLVNILNQPSNFLSTIQIGITLINI
LAGASLAEALSSRLAPLLGGTALAKTLAQIIVLAVLTYVSLVFGELYPKRIAQNLKEKLALRVAPPIQFLGKVMKPFVWF
LASSTNFLSRLTPMKFDDLDEGMTRDEIEYLLNTNDEALDANEREMITGVFSLDELVAREIMVPRTDAFMIDINDDSREN
ITAILSETYSRVPVYDDDKDNILGILHVKKLLRYSFDHGFDDIDLREILQEPLFVPETIFVDDLMRQMRKTQNQMAVLLN
EYGGVEGVVTLEDLLEEIVGEIDDETDIAEEEVFKIGENLYVVQGKMTLNDFNEEFDTHLESNDVDTIAGYFLATTGKIP
AKGQQIVCKVDNDEDHFSLTSLEVSGKRVVKLRVEFDVEPEETEIKKNY
>Mature_448_residues
SNPDPESVSILLQILLLIFLTALNAFFSASEMAMVSLSRTKVEQKASEGDKKYINLVNILNQPSNFLSTIQIGITLINIL
AGASLAEALSSRLAPLLGGTALAKTLAQIIVLAVLTYVSLVFGELYPKRIAQNLKEKLALRVAPPIQFLGKVMKPFVWFL
ASSTNFLSRLTPMKFDDLDEGMTRDEIEYLLNTNDEALDANEREMITGVFSLDELVAREIMVPRTDAFMIDINDDSRENI
TAILSETYSRVPVYDDDKDNILGILHVKKLLRYSFDHGFDDIDLREILQEPLFVPETIFVDDLMRQMRKTQNQMAVLLNE
YGGVEGVVTLEDLLEEIVGEIDDETDIAEEEVFKIGENLYVVQGKMTLNDFNEEFDTHLESNDVDTIAGYFLATTGKIPA
KGQQIVCKVDNDEDHFSLTSLEVSGKRVVKLRVEFDVEPEETEIKKNY

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=403, Percent_Identity=32.5062034739454, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI40068055, Length=358, Percent_Identity=24.8603351955307, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI40068053, Length=358, Percent_Identity=24.8603351955307, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI145693175, Length=387, Percent_Identity=29.7157622739018, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790664, Length=404, Percent_Identity=25.990099009901, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786879, Length=258, Percent_Identity=32.1705426356589, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082033, Length=246, Percent_Identity=28.8617886178862, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788119, Length=242, Percent_Identity=30.9917355371901, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17539402, Length=364, Percent_Identity=24.1758241758242, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324512, Length=277, Percent_Identity=25.6317689530686, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50484; Mature: 50353

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPDPESVSILLQILLLIFLTALNAFFSASEMAMVSLSRTKVEQKASEGDKKYINLVNI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LNQPSNFLSTIQIGITLINILAGASLAEALSSRLAPLLGGTALAKTLAQIIVLAVLTYVS
HCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LVFGELYPKRIAQNLKEKLALRVAPPIQFLGKVMKPFVWFLASSTNFLSRLTPMKFDDLD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
EGMTRDEIEYLLNTNDEALDANEREMITGVFSLDELVAREIMVPRTDAFMIDINDDSREN
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
ITAILSETYSRVPVYDDDKDNILGILHVKKLLRYSFDHGFDDIDLREILQEPLFVPETIF
HHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHH
VDDLMRQMRKTQNQMAVLLNEYGGVEGVVTLEDLLEEIVGEIDDETDIAEEEVFKIGENL
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHCCCE
YVVQGKMTLNDFNEEFDTHLESNDVDTIAGYFLATTGKIPAKGQQIVCKVDNDEDHFSLT
EEEEECEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEE
SLEVSGKRVVKLRVEFDVEPEETEIKKNY
EEEECCCEEEEEEEEECCCCCHHHHCCCC
>Mature Secondary Structure 
SNPDPESVSILLQILLLIFLTALNAFFSASEMAMVSLSRTKVEQKASEGDKKYINLVNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LNQPSNFLSTIQIGITLINILAGASLAEALSSRLAPLLGGTALAKTLAQIIVLAVLTYVS
HCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LVFGELYPKRIAQNLKEKLALRVAPPIQFLGKVMKPFVWFLASSTNFLSRLTPMKFDDLD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
EGMTRDEIEYLLNTNDEALDANEREMITGVFSLDELVAREIMVPRTDAFMIDINDDSREN
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
ITAILSETYSRVPVYDDDKDNILGILHVKKLLRYSFDHGFDDIDLREILQEPLFVPETIF
HHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHH
VDDLMRQMRKTQNQMAVLLNEYGGVEGVVTLEDLLEEIVGEIDDETDIAEEEVFKIGENL
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHCCCE
YVVQGKMTLNDFNEEFDTHLESNDVDTIAGYFLATTGKIPAKGQQIVCKVDNDEDHFSLT
EEEEECEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEE
SLEVSGKRVVKLRVEFDVEPEETEIKKNY
EEEECCCEEEEEEEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]