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The map label for this gene is pepT

Identifier: 15673792

GI number: 15673792

Start: 1877242

End: 1878483

Strand: Reverse

Name: pepT

Synonym: L60596

Alternate gene names: 15673792

Gene position: 1878483-1877242 (Counterclockwise)

Preceding gene: 15673793

Following gene: 30024056

Centisome position: 79.41

GC content: 36.39

Gene sequence:

>1242_bases
ATGAAGTACGAAAAACTGTTACCACGTTTTCTTGAATATGTTAAAGTAAATACACGTTCAGATGAAAACAGCACAACAAC
ACCTTCAACTCAAGCGCTCGTAGAATTTGCCCACAAAATGGGTGAAGATATGAAAGCCCTTGGTCTCAAAGATGTTCATT
ATCTTGAATCAAATGGTTATGTTATCGGTACAATTCCTGCAAATACAGATAAAAAAGTGCGCAAAATTGGACTTTTAGCT
CACTTGGATACTGCTGATTTCAACGCAGAGGGTGTTAACCCACAAATTTTGGAAAATTATGATGGTGAATCTGTGATTAA
ACTTGGTGATACTGAGTTTACACTTGATCCAAAAGATTTCCCAAATCTAAAAAACTACAAAGGGCAAACTTTAGTTCATA
CTGACGGAACAACTTTGCTTGGTTCAGATGATAAATCTGGTGTAGCTGAAATCATGACTTTAGCTGACTATCTATTGAAT
ATTAATCCTGATTTTGAACACGGTGAAATTCGTGTTGGATTTGGTCCTGATGAAGAAATTGGTGTAGGTGCTGATAAATT
TGACGTAGCTGACTTTGATGTTGACTTTGCTTACACTGTAGATGGTGGACCACTTGGAGAACTTCAATATGAAACTTTCT
CAGCAGCTGGTGCAGTGATTGAGTTCCAAGGTAAAAATGTTCACCCAGGGACAGCAAAAAATACAATGGTTAATGCATTG
CAATTAGCAATTGACTACCACAATGCACTTCCAGAATTTGATCGTCCTGAAAAAACCGAAGGCCGTGAAGGTTTCTTCCA
TCTTTTAAAACTTGATGGTACACCAGAAGAAGCAAGAGCTCAATATATCATTCGTGACCATGAAGAAGGTAAATTCAACG
AACGTAAAGCTTTGATGCAAGAGATTGCAGATAAAATGAATGCTGAACTTGGTCAAAACCGTGTGAAACCAGTTATTAAA
GACCAATACTACAACATGGCTCAAATCATTGAAAAAGATATGTCAATTATTGATATTGCTAAAAAAGCAATGGAAAATCT
TGATATTGTCCCAATTATTGAACCAATTCGTGGTGGAACTGATGGGTCTAAAATTTCATTTATGGGACTTCCAACACCAA
ACCTTTTTGCAGGTGGTGAAAACATGCACGGACGTTTTGAATTTGTTTCTGTACAAACAATGGAAAAAGCTGTAGATACT
TTGCTTGAAATCATTCGTTTGAACAATGAAGTAGTAAAATAA

Upstream 100 bases:

>100_bases
AAATCTTTCATTATTGCTCAAATTCAACAAACCACAGCTATTGAGCCGTTCATCTCACTTGGAGACAAATAGGCTATTAG
AATAAATTTAAGGAGAACAA

Downstream 100 bases:

>100_bases
AAGAAAAAGAGAGAGTAATTAGTTTTTAAACTCGATAATAAAAGAACAAGTCGCCCAAGAAGGTTTTTGATTAAAAATCT
TCATGAGCGGCTTGCTTTGC

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGYVIGTIPANTDKKVRKIGLLA
HLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDFPNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLN
INPDFEHGEIRVGFGPDEEIGVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNAL
QLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQEIADKMNAELGQNRVKPVIK
DQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGTDGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDT
LLEIIRLNNEVVK

Sequences:

>Translated_413_residues
MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGYVIGTIPANTDKKVRKIGLLA
HLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDFPNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLN
INPDFEHGEIRVGFGPDEEIGVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNAL
QLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQEIADKMNAELGQNRVKPVIK
DQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGTDGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDT
LLEIIRLNNEVVK
>Mature_413_residues
MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGYVIGTIPANTDKKVRKIGLLA
HLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDFPNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLN
INPDFEHGEIRVGFGPDEEIGVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNAL
QLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQEIADKMNAELGQNRVKPVIK
DQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGTDGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDT
LLEIIRLNNEVVK

Specific function: Cleaves the N-terminal amino acid of tripeptides

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family

Homologues:

Organism=Escherichia coli, GI1787372, Length=409, Percent_Identity=47.921760391198, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPT_LACLA (Q9CEM7)

Other databases:

- EMBL:   AE005176
- PIR:   B86851
- RefSeq:   NP_267967.1
- ProteinModelPortal:   Q9CEM7
- SMR:   Q9CEM7
- GeneID:   1115475
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L60596
- NMPDR:   fig|272623.1.peg.1856
- HOGENOM:   HBG288638
- OMA:   HMDTAPD
- ProtClustDB:   PRK05469
- BioCyc:   LLAC272623:L60596-MONOMER
- BRENDA:   3.4.11.4
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00550
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161
- PIRSF:   PIRSF037215
- TIGRFAMs:   TIGR01882

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.4.11.4

Molecular weight: Translated: 45972; Mature: 45972

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 83-83 ACT_SITE 178-178

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGY
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCE
VIGTIPANTDKKVRKIGLLAHLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDF
EEEEECCCCCHHHHHHHHEEEECCCCCCCCCCCHHHHHCCCCCEEEEECCCEEEECCCCC
PNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLNINPDFEHGEIRVGFGPDEEI
CCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCC
GVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNAL
CCCCCCCEEEECCCEEEEEECCCCCCCEEEHHHHCCCEEEEECCCCCCCCCCHHHHHHHH
QLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQ
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHEEEEECCCCCCCHHHHHHHH
EIADKMNAELGQNRVKPVIKDQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCC
DGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDTLLEIIRLNNEVVK
CCCEEEEEECCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCHHHCC
>Mature Secondary Structure
MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGY
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCE
VIGTIPANTDKKVRKIGLLAHLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDF
EEEEECCCCCHHHHHHHHEEEECCCCCCCCCCCHHHHHCCCCCEEEEECCCEEEECCCCC
PNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLNINPDFEHGEIRVGFGPDEEI
CCCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCC
GVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNAL
CCCCCCCEEEECCCEEEEEECCCCCCCEEEHHHHCCCEEEEECCCCCCCCCCHHHHHHHH
QLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQ
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHEEEEECCCCCCCHHHHHHHH
EIADKMNAELGQNRVKPVIKDQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCC
DGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDTLLEIIRLNNEVVK
CCCEEEEEECCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471