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The map label for this gene is aroK

Identifier: 15673725

GI number: 15673725

Start: 1801002

End: 1801490

Strand: Reverse

Name: aroK

Synonym: L0056

Alternate gene names: 15673725

Gene position: 1801490-1801002 (Counterclockwise)

Preceding gene: 15673726

Following gene: 15673724

Centisome position: 76.15

GC content: 34.56

Gene sequence:

>489_bases
ATGAGTATCATTTTAATTGGATTTATGGGTGCGGGAAAGTCCACAGTAGCAAAACTTTTAACAGAAAATTTTACTGATTT
GGATCAATTAATTGAAGAAGAAATTGAGATGACAATTGCTGAATTTTTTGAATTATTTGGGGAAGCTGATTTTCGTAAAA
TTGAAAATGAGGTTTTTGAACTTGCGCTGCAAAAGAATATAATTATTGCAACGGGTGGTGGAATAATTGAAAATCCAAAG
AATTTAGAGGCTCTTGATAGAGAAGCTGGAGTTGTCTTTTTGACCGCTGATTTTGAAACGCTTTGGGAACGAATTTCGAT
GGATTTGCAGAATGTTCGTCCTCTAGCGCAGGATAAAAAGGCCGCTCAACTTTTATTTGAAAAAAGAAAAAATGACTATG
CAAAAGTGGCCGATTTAACGATTGATGTTACTGATAAGAGTCCTGAGCAAATTGTAGAAGAGATTCGTGAAAAATGGGGG
ATAAATTAA

Upstream 100 bases:

>100_bases
TTGAACGTGCCGAAGCAATTCAAACAAGTTATCCAAGTTTCTTTGACGATTTAGAACAATTGTCGGAAAATATTTGAACT
TAAGTGATTGGAAGTAAAAA

Downstream 100 bases:

>100_bases
GATGAAAATTGCGTATTTAGGACCTCGTGGCTCTTTTTGTTCGGTGGTGGCTGAGACAGCATTTGTATCAGAAGAATTAT
TTGCTTATGATAGTATTCTG

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSIILIGFMGAGKSTVAKLLTENFTDLDQLIEEEIEMTIAEFFELFGEADFRKIENEVFELALQKNIIIATGGGIIENPK
NLEALDREAGVVFLTADFETLWERISMDLQNVRPLAQDKKAAQLLFEKRKNDYAKVADLTIDVTDKSPEQIVEEIREKWG
IN

Sequences:

>Translated_162_residues
MSIILIGFMGAGKSTVAKLLTENFTDLDQLIEEEIEMTIAEFFELFGEADFRKIENEVFELALQKNIIIATGGGIIENPK
NLEALDREAGVVFLTADFETLWERISMDLQNVRPLAQDKKAAQLLFEKRKNDYAKVADLTIDVTDKSPEQIVEEIREKWG
IN
>Mature_161_residues
SIILIGFMGAGKSTVAKLLTENFTDLDQLIEEEIEMTIAEFFELFGEADFRKIENEVFELALQKNIIIATGGGIIENPKN
LEALDREAGVVFLTADFETLWERISMDLQNVRPLAQDKKAAQLLFEKRKNDYAKVADLTIDVTDKSPEQIVEEIREKWGI
N

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI1786587, Length=162, Percent_Identity=34.5679012345679, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI87082255, Length=163, Percent_Identity=32.5153374233129, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_LACLA (Q9CEU1)

Other databases:

- EMBL:   AE005176
- PIR:   G86842
- RefSeq:   NP_267899.1
- ProteinModelPortal:   Q9CEU1
- SMR:   Q9CEU1
- GeneID:   1115406
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0056
- NMPDR:   fig|272623.1.peg.1787
- HOGENOM:   HBG335815
- OMA:   SITTIFA
- ProtClustDB:   CLSK697918
- BioCyc:   LLAC272623:L0056-MONOMER
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 18383; Mature: 18252

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 28-28 BINDING 52-52 BINDING 73-73 BINDING 113-113 BINDING 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILIGFMGAGKSTVAKLLTENFTDLDQLIEEEIEMTIAEFFELFGEADFRKIENEVFE
CEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LALQKNIIIATGGGIIENPKNLEALDREAGVVFLTADFETLWERISMDLQNVRPLAQDKK
HHHHCCEEEEECCCCCCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHH
AAQLLFEKRKNDYAKVADLTIDVTDKSPEQIVEEIREKWGIN
HHHHHHHHHCCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIILIGFMGAGKSTVAKLLTENFTDLDQLIEEEIEMTIAEFFELFGEADFRKIENEVFE
EEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LALQKNIIIATGGGIIENPKNLEALDREAGVVFLTADFETLWERISMDLQNVRPLAQDKK
HHHHCCEEEEECCCCCCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHH
AAQLLFEKRKNDYAKVADLTIDVTDKSPEQIVEEIREKWGIN
HHHHHHHHHCCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471