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The map label for this gene is aroA

Identifier: 15673726

GI number: 15673726

Start: 1801514

End: 1802806

Strand: Reverse

Name: aroA

Synonym: L0057

Alternate gene names: 15673726

Gene position: 1802806-1801514 (Counterclockwise)

Preceding gene: 15673727

Following gene: 15673725

Centisome position: 76.21

GC content: 37.9

Gene sequence:

>1293_bases
ATGAAATTAAAGATAAATTCGCAAGGCTTAAAAGGACGTTTAAAAGTTCCAGGAGATAAATCAATCTCACATCGTAGTAT
TATGTTTGGCTCTATTGCTAAAGGAAAAACTGTTATTTATGATATTTTACGTGGAGAAGATGTCTTATCTACTATTGAAG
CTTTCCGTGCGATGGGAGTTGAAATTGAAGATAAGGGTGAGGTGATTACTGTCCACGGTAAAGGAATTTCAGAACTTAAG
GCTCCTGAAAAAGCACTGGATATGGGAAATTCCGGAACTTCAACTCGTCTTTTATCGGGAATTTTAGCAGGCCTTCCTTT
TGAAACTACTTTGTTTGGTGATGACAGTTTATCAAAAAGACCAATGGATCGTGTAGCAACTCCTTTACAATTGATGGGGG
CAGAAATTACTGGTCAAACCGATAAGGTTAAATTACCGATGACAATTAAAGGAAGCACGCATTTGAAGGCAATTGACTAT
GTTCTTCCGGTGGCTTCGGCTCAGGTAAAATCAGCTGTAATTTTTGCTGCTTTACAGGCAGAAGGGCTGACGAAAGTTGT
TGAAAAGGAAAAAACACGCTCACATACCGAAGAAATGTTAGTTCAATTTGGTGGAGAACTAAAGGTTTCTGATAAAACAA
TTCTTGTACCTGGTGGACAAAAACTTGTGGGTCAAAAAGTAGTAGTTCCTGGAGATATTAGTTCGGCAGCTTTTTGGTTG
GTTGCGGCCTTGGTTGTTGAAAATTCAGAACTTATTTTAGAAAACGTTGGAGTTAATGAAACAAGAACTGGAATTATCGA
AGTCATTCAAGCAATGGGTGGACAGTTGGAAATTTTAGAGCAAGATAATGTGGCAAAGGCTGCAACTCTAAAAGTAAAAG
CTAGTCAATTGAAAGGAACTGAAATTTCAGGTGATTTAATTCCTAGATTAATTGATGAATTGCCAATCATTGCTCTCTTA
GCAACGCAAGCTCAAGGCCAAACAATTATTCGAGATGCGGCTGAGCTTAAAGTAAAAGAAACTGACCGAATTGCTGTTGT
CGCGAATGCTCTTAATAGTATGGGGGCCAAAATTCAACCAACAGATGATGGAATGATTATTCAAGGTGGAACGAAACTCC
ATGCTCCAGAAAATTCAATTAATACTTTAGGTGACCATAGAATTGGAATGATGGCTGCAATTGCAGCACTTTTGGTTAAA
AATGGGGAAATTGAGCTTGAACGTGCCGAAGCAATTCAAACAAGTTATCCAAGTTTCTTTGACGATTTAGAACAATTGTC
GGAAAATATTTGA

Upstream 100 bases:

>100_bases
TTCTTAGTCTTAAAATCTTAGGAAAAATTGTTGAAAATAAAAGGGCTCTGAGCGCCCTTTTATGCTATAATAAATACTAA
AAAATGTTTAGGATAATATA

Downstream 100 bases:

>100_bases
ACTTAAGTGATTGGAAGTAAAAAATGAGTATCATTTTAATTGGATTTATGGGTGCGGGAAAGTCCACAGTAGCAAAACTT
TTAACAGAAAATTTTACTGA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTVIYDILRGEDVLSTIEAFRAMGVEIEDKGEVITVHGKGISELK
APEKALDMGNSGTSTRLLSGILAGLPFETTLFGDDSLSKRPMDRVATPLQLMGAEITGQTDKVKLPMTIKGSTHLKAIDY
VLPVASAQVKSAVIFAALQAEGLTKVVEKEKTRSHTEEMLVQFGGELKVSDKTILVPGGQKLVGQKVVVPGDISSAAFWL
VAALVVENSELILENVGVNETRTGIIEVIQAMGGQLEILEQDNVAKAATLKVKASQLKGTEISGDLIPRLIDELPIIALL
ATQAQGQTIIRDAAELKVKETDRIAVVANALNSMGAKIQPTDDGMIIQGGTKLHAPENSINTLGDHRIGMMAAIAALLVK
NGEIELERAEAIQTSYPSFFDDLEQLSENI

Sequences:

>Translated_430_residues
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTVIYDILRGEDVLSTIEAFRAMGVEIEDKGEVITVHGKGISELK
APEKALDMGNSGTSTRLLSGILAGLPFETTLFGDDSLSKRPMDRVATPLQLMGAEITGQTDKVKLPMTIKGSTHLKAIDY
VLPVASAQVKSAVIFAALQAEGLTKVVEKEKTRSHTEEMLVQFGGELKVSDKTILVPGGQKLVGQKVVVPGDISSAAFWL
VAALVVENSELILENVGVNETRTGIIEVIQAMGGQLEILEQDNVAKAATLKVKASQLKGTEISGDLIPRLIDELPIIALL
ATQAQGQTIIRDAAELKVKETDRIAVVANALNSMGAKIQPTDDGMIIQGGTKLHAPENSINTLGDHRIGMMAAIAALLVK
NGEIELERAEAIQTSYPSFFDDLEQLSENI
>Mature_430_residues
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTVIYDILRGEDVLSTIEAFRAMGVEIEDKGEVITVHGKGISELK
APEKALDMGNSGTSTRLLSGILAGLPFETTLFGDDSLSKRPMDRVATPLQLMGAEITGQTDKVKLPMTIKGSTHLKAIDY
VLPVASAQVKSAVIFAALQAEGLTKVVEKEKTRSHTEEMLVQFGGELKVSDKTILVPGGQKLVGQKVVVPGDISSAAFWL
VAALVVENSELILENVGVNETRTGIIEVIQAMGGQLEILEQDNVAKAATLKVKASQLKGTEISGDLIPRLIDELPIIALL
ATQAQGQTIIRDAAELKVKETDRIAVVANALNSMGAKIQPTDDGMIIQGGTKLHAPENSINTLGDHRIGMMAAIAALLVK
NGEIELERAEAIQTSYPSFFDDLEQLSENI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=25.9174311926606, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=461, Percent_Identity=24.5119305856833, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_LACLA (Q9CEU0)

Other databases:

- EMBL:   AE005176
- PIR:   H86842
- RefSeq:   NP_267900.1
- ProteinModelPortal:   Q9CEU0
- SMR:   Q9CEU0
- GeneID:   1115407
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0057
- NMPDR:   fig|272623.1.peg.1788
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   LLAC272623:L0057-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45959; Mature: 45959

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTVIYDILRGEDVLSTIEAFRAMGV
CEEEECCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHCC
EIEDKGEVITVHGKGISELKAPEKALDMGNSGTSTRLLSGILAGLPFETTLFGDDSLSKR
EEECCCCEEEEECCCHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PMDRVATPLQLMGAEITGQTDKVKLPMTIKGSTHLKAIDYVLPVASAQVKSAVIFAALQA
CHHHHCCCHHHHCCEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLTKVVEKEKTRSHTEEMLVQFGGELKVSDKTILVPGGQKLVGQKVVVPGDISSAAFWL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCHHCCCEEEECCCCCHHHHHH
VAALVVENSELILENVGVNETRTGIIEVIQAMGGQLEILEQDNVAKAATLKVKASQLKGT
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEHHHCCCC
EISGDLIPRLIDELPIIALLATQAQGQTIIRDAAELKVKETDRIAVVANALNSMGAKIQP
CCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCEECCCCCCHHHHHHHHHCCCEEEE
TDDGMIIQGGTKLHAPENSINTLGDHRIGMMAAIAALLVKNGEIELERAEAIQTSYPSFF
CCCCEEEECCCEECCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCHHH
DDLEQLSENI
HHHHHHHHCC
>Mature Secondary Structure
MKLKINSQGLKGRLKVPGDKSISHRSIMFGSIAKGKTVIYDILRGEDVLSTIEAFRAMGV
CEEEECCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHCC
EIEDKGEVITVHGKGISELKAPEKALDMGNSGTSTRLLSGILAGLPFETTLFGDDSLSKR
EEECCCCEEEEECCCHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PMDRVATPLQLMGAEITGQTDKVKLPMTIKGSTHLKAIDYVLPVASAQVKSAVIFAALQA
CHHHHCCCHHHHCCEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLTKVVEKEKTRSHTEEMLVQFGGELKVSDKTILVPGGQKLVGQKVVVPGDISSAAFWL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCHHCCCEEEECCCCCHHHHHH
VAALVVENSELILENVGVNETRTGIIEVIQAMGGQLEILEQDNVAKAATLKVKASQLKGT
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEHHHCCCC
EISGDLIPRLIDELPIIALLATQAQGQTIIRDAAELKVKETDRIAVVANALNSMGAKIQP
CCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCEECCCCCCHHHHHHHHHCCCEEEE
TDDGMIIQGGTKLHAPENSINTLGDHRIGMMAAIAALLVKNGEIELERAEAIQTSYPSFF
CCCCEEEECCCEECCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCHHH
DDLEQLSENI
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471