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The map label for this gene is xylA

Identifier: 15673491

GI number: 15673491

Start: 1549053

End: 1550372

Strand: Reverse

Name: xylA

Synonym: L0230

Alternate gene names: 15673491

Gene position: 1550372-1549053 (Counterclockwise)

Preceding gene: 15673493

Following gene: 15673490

Centisome position: 65.54

GC content: 37.05

Gene sequence:

>1320_bases
ATGGCTTACTTTAACGACATCGCACCTATCAAATACGAAGGTACAAAAACTAAAAATATGTTTGCCTTTCGCCATTATAA
TCCAGAAGAAGTAGTTGCTGGTAAAACAATGGAAGAACAACTTCATTTTGCCCTTGCATTTTGGCATACAATTACAATGG
ATGGGTCAGACCCCTTTGGGGGAGCAACAATGGAACGTCCTTGGGATTTGGAAGGTGGTTCTGAACTTGACCGTGCTCAC
CGTCGAGTAGATGCTTTCTTTGAAATTGCTGAAAAATTAGGTGTTAAATATTATTGTTTCCATGATATTGATATTGCACC
TACTGGAAATTCTTTGAAAGAATTTTATGCTAATTTGGACGAAATTACTGACCACCTTCTTGAAAAACAAAAAGCAACAG
GGATTAAATTACTTTGGAATACAGCAAACATGTTTTCAAATCCCCGCTATATGAATGGTGTTTCAACTTCTAACCGTGCT
GAAGTCTTTGCTTATGGTGCTGCACAAGTTAAAAAAGGTCTTGAACTTTCTAAAAAACTCGGTGGCGAAAATTATGTCTT
CTGGGGTGGTCGTGAAGGTTATGAATCACTTTTGAACACAGATAGGGGTCTTGAAATGGACCACATGGCAAAATTCTTCC
ATTTGGCAATTGATTATGCAAAATCAATCAACCACTTGCCTATTTTCTTGATTGAACCAAAACCAAAAGAACCAATGACT
CACCAATATGATTTTGACGCAGCAACAGCTCTTGCTTTCTTGCAAAAATATGATTTGGACAAATATTTCAAACTCAATCT
TGAAACAAATCATGCTTGGCTTGTTGGTCACACTTTTGAACACGAATTAAATACTGCACGTACTTTCAATGCTTTGGGTT
CTATTGATGCCAATCAAGGAAATTACTTGCTTGGTTGGGATACAGATGAATTCCCAACACTTGTTATTGATATCACACTT
GCGATGCACCAAATTCTTTTGAACGGTGGACTTGGCAAAGGTGGAATTAACTTTGATGCGAAAGTACGTCGTACAAGTTT
CAAAGCAGAAGATTTAATTCTTGCTCATATTGCAGGGATGGATACTTATGCGCGTGCTTTGAAAGGTGCAGCAGCAATCA
TTGAAGATAAATTCTTGTCTGATATTGTTGACGAACGTTATACTTCATACAAAAATACAGAAGTTGGTCAATCCATTGAA
AATGGAACAGCAACTTTTGAAAGTCTTGCCGCATTTGCACTTGAACATGGTGACGATATTGAACTTGATTCTAATCACTT
GGAATACATCAAATCAGTATTGAATGACTATCTTGTTTAA

Upstream 100 bases:

>100_bases
TCCTAATCACTATTATTATGACATATATTACAAGAAATGTATAGTAGTAATTACGAGTTTGAAAATAATATTAATATCAT
AAAGAGGAGGAGCTATAAAA

Downstream 100 bases:

>100_bases
AATTTAGAACTTAAAAGAGGGCGAGGAATTCCTCGCCCTCTTTTATTACGAGGAATAATAATGACTTACGTGTTAGGAAT
TGACTTAGGAACATCAAGTC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAYFNDIAPIKYEGTKTKNMFAFRHYNPEEVVAGKTMEEQLHFALAFWHTITMDGSDPFGGATMERPWDLEGGSELDRAH
RRVDAFFEIAEKLGVKYYCFHDIDIAPTGNSLKEFYANLDEITDHLLEKQKATGIKLLWNTANMFSNPRYMNGVSTSNRA
EVFAYGAAQVKKGLELSKKLGGENYVFWGGREGYESLLNTDRGLEMDHMAKFFHLAIDYAKSINHLPIFLIEPKPKEPMT
HQYDFDAATALAFLQKYDLDKYFKLNLETNHAWLVGHTFEHELNTARTFNALGSIDANQGNYLLGWDTDEFPTLVIDITL
AMHQILLNGGLGKGGINFDAKVRRTSFKAEDLILAHIAGMDTYARALKGAAAIIEDKFLSDIVDERYTSYKNTEVGQSIE
NGTATFESLAAFALEHGDDIELDSNHLEYIKSVLNDYLV

Sequences:

>Translated_439_residues
MAYFNDIAPIKYEGTKTKNMFAFRHYNPEEVVAGKTMEEQLHFALAFWHTITMDGSDPFGGATMERPWDLEGGSELDRAH
RRVDAFFEIAEKLGVKYYCFHDIDIAPTGNSLKEFYANLDEITDHLLEKQKATGIKLLWNTANMFSNPRYMNGVSTSNRA
EVFAYGAAQVKKGLELSKKLGGENYVFWGGREGYESLLNTDRGLEMDHMAKFFHLAIDYAKSINHLPIFLIEPKPKEPMT
HQYDFDAATALAFLQKYDLDKYFKLNLETNHAWLVGHTFEHELNTARTFNALGSIDANQGNYLLGWDTDEFPTLVIDITL
AMHQILLNGGLGKGGINFDAKVRRTSFKAEDLILAHIAGMDTYARALKGAAAIIEDKFLSDIVDERYTSYKNTEVGQSIE
NGTATFESLAAFALEHGDDIELDSNHLEYIKSVLNDYLV
>Mature_438_residues
AYFNDIAPIKYEGTKTKNMFAFRHYNPEEVVAGKTMEEQLHFALAFWHTITMDGSDPFGGATMERPWDLEGGSELDRAHR
RVDAFFEIAEKLGVKYYCFHDIDIAPTGNSLKEFYANLDEITDHLLEKQKATGIKLLWNTANMFSNPRYMNGVSTSNRAE
VFAYGAAQVKKGLELSKKLGGENYVFWGGREGYESLLNTDRGLEMDHMAKFFHLAIDYAKSINHLPIFLIEPKPKEPMTH
QYDFDAATALAFLQKYDLDKYFKLNLETNHAWLVGHTFEHELNTARTFNALGSIDANQGNYLLGWDTDEFPTLVIDITLA
MHQILLNGGLGKGGINFDAKVRRTSFKAEDLILAHIAGMDTYARALKGAAAIIEDKFLSDIVDERYTSYKNTEVGQSIEN
GTATFESLAAFALEHGDDIELDSNHLEYIKSVLNDYLV

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=437, Percent_Identity=48.0549199084668, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_LACLA (Q9CFG7)

Other databases:

- EMBL:   AF092040
- EMBL:   AF092041
- EMBL:   AF092042
- EMBL:   AJ344090
- EMBL:   AE005176
- PIR:   E86813
- RefSeq:   NP_267665.1
- ProteinModelPortal:   Q9CFG7
- SMR:   Q9CFG7
- GeneID:   1115166
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0230
- NMPDR:   fig|272623.1.peg.1550
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- BioCyc:   LLAC272623:L0230-MONOMER
- BRENDA:   5.3.1.5
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49618; Mature: 49487

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 101-101 ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYFNDIAPIKYEGTKTKNMFAFRHYNPEEVVAGKTMEEQLHFALAFWHTITMDGSDPFG
CCCCCCCCCEEECCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHEEEEEEEECCCCCCC
GATMERPWDLEGGSELDRAHRRVDAFFEIAEKLGVKYYCFHDIDIAPTGNSLKEFYANLD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCHHHHHHHHHHH
EITDHLLEKQKATGIKLLWNTANMFSNPRYMNGVSTSNRAEVFAYGAAQVKKGLELSKKL
HHHHHHHHHHHCCCEEEEEECHHHCCCCCEECCCCCCCCCEEEEECHHHHHHHHHHHHHC
GGENYVFWGGREGYESLLNTDRGLEMDHMAKFFHLAIDYAKSINHLPIFLIEPKPKEPMT
CCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
HQYDFDAATALAFLQKYDLDKYFKLNLETNHAWLVGHTFEHELNTARTFNALGSIDANQG
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHHHHHCCCCCCCC
NYLLGWDTDEFPTLVIDITLAMHQILLNGGLGKGGINFDAKVRRTSFKAEDLILAHIAGM
CEEEECCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEHHCCCCHHHHHHHHHHCC
DTYARALKGAAAIIEDKFLSDIVDERYTSYKNTEVGQSIENGTATFESLAAFALEHGDDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHCCHHHHHHHHHHHHCCCCCC
ELDSNHLEYIKSVLNDYLV
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYFNDIAPIKYEGTKTKNMFAFRHYNPEEVVAGKTMEEQLHFALAFWHTITMDGSDPFG
CCCCCCCCEEECCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHEEEEEEEECCCCCCC
GATMERPWDLEGGSELDRAHRRVDAFFEIAEKLGVKYYCFHDIDIAPTGNSLKEFYANLD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCHHHHHHHHHHH
EITDHLLEKQKATGIKLLWNTANMFSNPRYMNGVSTSNRAEVFAYGAAQVKKGLELSKKL
HHHHHHHHHHHCCCEEEEEECHHHCCCCCEECCCCCCCCCEEEEECHHHHHHHHHHHHHC
GGENYVFWGGREGYESLLNTDRGLEMDHMAKFFHLAIDYAKSINHLPIFLIEPKPKEPMT
CCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
HQYDFDAATALAFLQKYDLDKYFKLNLETNHAWLVGHTFEHELNTARTFNALGSIDANQG
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECHHHHHHHHHHHHHHCCCCCCCC
NYLLGWDTDEFPTLVIDITLAMHQILLNGGLGKGGINFDAKVRRTSFKAEDLILAHIAGM
CEEEECCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCEEHHCCCCHHHHHHHHHHCC
DTYARALKGAAAIIEDKFLSDIVDERYTSYKNTEVGQSIENGTATFESLAAFALEHGDDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHCCHHHHHHHHHHHHCCCCCC
ELDSNHLEYIKSVLNDYLV
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471