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The map label for this gene is xylB

Identifier: 15673490

GI number: 15673490

Start: 1547487

End: 1548992

Strand: Reverse

Name: xylB

Synonym: L0231

Alternate gene names: 15673490

Gene position: 1548992-1547487 (Counterclockwise)

Preceding gene: 15673491

Following gene: 15673489

Centisome position: 65.48

GC content: 36.85

Gene sequence:

>1506_bases
ATGACTTACGTGTTAGGAATTGACTTAGGAACATCAAGTCTTAAAGGAATTTTGATGGATGAAGTTGGTAATTTAATTAC
AACAAAATCTGCTGAATACCAAATTGATACGCCCAAACAAGGCTATTCTGAACAACGTCCAGAATATTGGATTGTGGCAC
TTGAATCAGTACTGACCGGTTTGTCAGTAGAAATTTCAGATTTTGGTCAGCAACTTGCAGGCATTAGTTTTTCGGGGCAA
ATGCATTCATTAGTCGTTTTAGATGACAATAATAAACCAGTTTATCCAGCAATTCTTTGGAATGATGTGAGAACAAGCAA
ACAATGTCAAGAAATTACTGACAGACTTGGTCAGCGACTTTTAGAGATTACAAAAAATATTGCTCTTGAAGGATTTACCT
TACCAAAAATTCTTTGGCTCCAAGAAAATGAACCAGAGGTTTGGTCAAGAGTTAAAAAAATAATGTTGCCAAAAGATTAC
TTGAGCCTTTGGCTGACAGGAAATATTTATACCGAATTTTCTGACGCAGCAGGAACTTTACTTTTAGATATTGAGAAAAA
ACAATGGTCAGAGGAAATTACTGACGCATTCAATATTGATAGGAGAATTCTACCTGAATTGATTGAATCCACTGACCGAA
CAGGATTTGTCAAAGCAGAAATAGCTGAACGCTATAAACTGACAAATGAAGTAAAAGTATTTGCTGGTGGAGCCGATAAT
GCTGCCGCCGCTCTGGGTGTTGGTTTAATCAATGAAGAAGTGGGCTTGATTTCAATGGGAACCTCCGGAGTCGTTTCCGC
TTATGAACCTAAAATTGCAGATTATAAAGGAAAACTTCATTTCTTTAATCACACGGTTCCGGGTGCTTGTTACTCAATGG
GAGTAACCTTGGCTGCCGGAAATTCTTTAAACTGGTATAAGGAAACTTTTGGAAAAGGCTTGAGTTTCAATGAACTTTTG
TCAGAAGTTTACACAGTTTCTCCTGGTTCAGAAGGATTGCTCTTTACGCCATATATTGTAGGTGAAAGAACACCACATTT
TGATTCAAAAATTCGCGGAAGTTTTATAGGAATTTCTGCTCATCATGAACAAAAACATTTTTCAAGAGCAGTGCTTGAAG
GAATTACCTTTTCATTGCGTGATTCTAAAGATATCATGGAAAAAACGAAAAACAAGAAGTTTAAACGTTTGATTTCCGTA
GGTGGGGGTGCGCAAAATCCCGACATTATGCAAATGCAAGCAGATATTTTTAATTCTGAAATGATTCGCTTAACGGTTGA
GCAGGGACCGGGACTTGGTGCTTGTATGATTGCTGCTTTTGGTTGCGGACTTTTTGATAGCTTAGAAGCGGTCACTAAAG
CTTTTGTTCATTACAAGGAAGCCAGTTTCATACCAAATCCAAAAAATGTAGCACGTTATGAGCAAATTTATCAAATTTGG
AAACAAGTTTATAAAAATACCTCTGAAATTTCTCATCAATTAGTAGAATTCAATGACGAAGGTTAA

Upstream 100 bases:

>100_bases
GGAATACATCAAATCAGTATTGAATGACTATCTTGTTTAAAATTTAGAACTTAAAAGAGGGCGAGGAATTCCTCGCCCTC
TTTTATTACGAGGAATAATA

Downstream 100 bases:

>100_bases
TTATGACATTTACCATTTCCAAAGAATCTTTGCCTTTTAGAGCTGACAAATCAATTAGTCAGATTACATTATCAAATGAA
CGACTCACCATCGTTGTCCA

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTYVLGIDLGTSSLKGILMDEVGNLITTKSAEYQIDTPKQGYSEQRPEYWIVALESVLTGLSVEISDFGQQLAGISFSGQ
MHSLVVLDDNNKPVYPAILWNDVRTSKQCQEITDRLGQRLLEITKNIALEGFTLPKILWLQENEPEVWSRVKKIMLPKDY
LSLWLTGNIYTEFSDAAGTLLLDIEKKQWSEEITDAFNIDRRILPELIESTDRTGFVKAEIAERYKLTNEVKVFAGGADN
AAAALGVGLINEEVGLISMGTSGVVSAYEPKIADYKGKLHFFNHTVPGACYSMGVTLAAGNSLNWYKETFGKGLSFNELL
SEVYTVSPGSEGLLFTPYIVGERTPHFDSKIRGSFIGISAHHEQKHFSRAVLEGITFSLRDSKDIMEKTKNKKFKRLISV
GGGAQNPDIMQMQADIFNSEMIRLTVEQGPGLGACMIAAFGCGLFDSLEAVTKAFVHYKEASFIPNPKNVARYEQIYQIW
KQVYKNTSEISHQLVEFNDEG

Sequences:

>Translated_501_residues
MTYVLGIDLGTSSLKGILMDEVGNLITTKSAEYQIDTPKQGYSEQRPEYWIVALESVLTGLSVEISDFGQQLAGISFSGQ
MHSLVVLDDNNKPVYPAILWNDVRTSKQCQEITDRLGQRLLEITKNIALEGFTLPKILWLQENEPEVWSRVKKIMLPKDY
LSLWLTGNIYTEFSDAAGTLLLDIEKKQWSEEITDAFNIDRRILPELIESTDRTGFVKAEIAERYKLTNEVKVFAGGADN
AAAALGVGLINEEVGLISMGTSGVVSAYEPKIADYKGKLHFFNHTVPGACYSMGVTLAAGNSLNWYKETFGKGLSFNELL
SEVYTVSPGSEGLLFTPYIVGERTPHFDSKIRGSFIGISAHHEQKHFSRAVLEGITFSLRDSKDIMEKTKNKKFKRLISV
GGGAQNPDIMQMQADIFNSEMIRLTVEQGPGLGACMIAAFGCGLFDSLEAVTKAFVHYKEASFIPNPKNVARYEQIYQIW
KQVYKNTSEISHQLVEFNDEG
>Mature_500_residues
TYVLGIDLGTSSLKGILMDEVGNLITTKSAEYQIDTPKQGYSEQRPEYWIVALESVLTGLSVEISDFGQQLAGISFSGQM
HSLVVLDDNNKPVYPAILWNDVRTSKQCQEITDRLGQRLLEITKNIALEGFTLPKILWLQENEPEVWSRVKKIMLPKDYL
SLWLTGNIYTEFSDAAGTLLLDIEKKQWSEEITDAFNIDRRILPELIESTDRTGFVKAEIAERYKLTNEVKVFAGGADNA
AAALGVGLINEEVGLISMGTSGVVSAYEPKIADYKGKLHFFNHTVPGACYSMGVTLAAGNSLNWYKETFGKGLSFNELLS
EVYTVSPGSEGLLFTPYIVGERTPHFDSKIRGSFIGISAHHEQKHFSRAVLEGITFSLRDSKDIMEKTKNKKFKRLISVG
GGAQNPDIMQMQADIFNSEMIRLTVEQGPGLGACMIAAFGCGLFDSLEAVTKAFVHYKEASFIPNPKNVARYEQIYQIWK
QVYKNTSEISHQLVEFNDEG

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Homo sapiens, GI42794763, Length=455, Percent_Identity=23.2967032967033, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI189409120, Length=455, Percent_Identity=23.956043956044, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4504007, Length=457, Percent_Identity=24.0700218818381, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI41393575, Length=450, Percent_Identity=23.1111111111111, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI18860918, Length=522, Percent_Identity=25.095785440613, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=34.0909090909091, Blast_Score=274, Evalue=9e-75,
Organism=Escherichia coli, GI1790005, Length=488, Percent_Identity=25.6147540983607, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1790361, Length=503, Percent_Identity=24.6520874751491, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1789168, Length=475, Percent_Identity=24.2105263157895, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787789, Length=517, Percent_Identity=22.4371373307544, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1789138, Length=503, Percent_Identity=22.8628230616302, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17554530, Length=545, Percent_Identity=22.5688073394495, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17535599, Length=443, Percent_Identity=24.8306997742664, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321633, Length=537, Percent_Identity=24.9534450651769, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17864214, Length=464, Percent_Identity=24.5689655172414, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655555, Length=486, Percent_Identity=23.4567901234568, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24655560, Length=486, Percent_Identity=23.4567901234568, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24655570, Length=486, Percent_Identity=23.4567901234568, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24655574, Length=486, Percent_Identity=23.4567901234568, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24655565, Length=486, Percent_Identity=23.4567901234568, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24654573, Length=393, Percent_Identity=24.9363867684478, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21356607, Length=565, Percent_Identity=24.2477876106195, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI19920476, Length=497, Percent_Identity=24.3460764587525, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656367, Length=508, Percent_Identity=21.8503937007874, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLB_LACLA (Q9CFG8)

Other databases:

- EMBL:   AE005176
- PIR:   D86813
- RefSeq:   NP_267664.1
- ProteinModelPortal:   Q9CFG8
- SMR:   Q9CFG8
- GeneID:   1115165
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0231
- NMPDR:   fig|272623.1.peg.1549
- HOGENOM:   HBG511469
- OMA:   HATERAH
- ProtClustDB:   CLSK2300427
- BioCyc:   LLAC272623:L0231-MONOMER
- BRENDA:   2.7.1.17
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000
- PANTHER:   PTHR10196
- TIGRFAMs:   TIGR01312

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.17

Molecular weight: Translated: 55814; Mature: 55683

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYVLGIDLGTSSLKGILMDEVGNLITTKSAEYQIDTPKQGYSEQRPEYWIVALESVLTG
CEEEEEEECCCHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCCCCEEEEEHHHHHCC
LSVEISDFGQQLAGISFSGQMHSLVVLDDNNKPVYPAILWNDVRTSKQCQEITDRLGQRL
CCEEHHHHHHHHCCCEECCCEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
LEITKNIALEGFTLPKILWLQENEPEVWSRVKKIMLPKDYLSLWLTGNIYTEFSDAAGTL
HHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHEEEEEECCEEEEECCCCCEE
LLDIEKKQWSEEITDAFNIDRRILPELIESTDRTGFVKAEIAERYKLTNEVKVFAGGADN
EEEECHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEEEECCCCC
AAAALGVGLINEEVGLISMGTSGVVSAYEPKIADYKGKLHFFNHTVPGACYSMGVTLAAG
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCEEEEEC
NSLNWYKETFGKGLSFNELLSEVYTVSPGSEGLLFTPYIVGERTPHFDSKIRGSFIGISA
CCCCHHHHHHCCCCCHHHHHHHHEECCCCCCCEEECCEEECCCCCCCCHHHCCCEEEEEC
HHEQKHFSRAVLEGITFSLRDSKDIMEKTKNKKFKRLISVGGGAQNPDIMQMQADIFNSE
CHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCE
MIRLTVEQGPGLGACMIAAFGCGLFDSLEAVTKAFVHYKEASFIPNPKNVARYEQIYQIW
EEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KQVYKNTSEISHQLVEFNDEG
HHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TYVLGIDLGTSSLKGILMDEVGNLITTKSAEYQIDTPKQGYSEQRPEYWIVALESVLTG
EEEEEEECCCHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCCCCEEEEEHHHHHCC
LSVEISDFGQQLAGISFSGQMHSLVVLDDNNKPVYPAILWNDVRTSKQCQEITDRLGQRL
CCEEHHHHHHHHCCCEECCCEEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
LEITKNIALEGFTLPKILWLQENEPEVWSRVKKIMLPKDYLSLWLTGNIYTEFSDAAGTL
HHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHEEEEEECCEEEEECCCCCEE
LLDIEKKQWSEEITDAFNIDRRILPELIESTDRTGFVKAEIAERYKLTNEVKVFAGGADN
EEEECHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEEEECCCCC
AAAALGVGLINEEVGLISMGTSGVVSAYEPKIADYKGKLHFFNHTVPGACYSMGVTLAAG
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCEEEEEC
NSLNWYKETFGKGLSFNELLSEVYTVSPGSEGLLFTPYIVGERTPHFDSKIRGSFIGISA
CCCCHHHHHHCCCCCHHHHHHHHEECCCCCCCEEECCEEECCCCCCCCHHHCCCEEEEEC
HHEQKHFSRAVLEGITFSLRDSKDIMEKTKNKKFKRLISVGGGAQNPDIMQMQADIFNSE
CHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCE
MIRLTVEQGPGLGACMIAAFGCGLFDSLEAVTKAFVHYKEASFIPNPKNVARYEQIYQIW
EEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KQVYKNTSEISHQLVEFNDEG
HHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471