Click here to switch to the map view.

The map label for this gene is dexB

Identifier: 15673475

GI number: 15673475

Start: 1524880

End: 1526427

Strand: Reverse

Name: dexB

Synonym: L124628

Alternate gene names: 15673475

Gene position: 1526427-1524880 (Counterclockwise)

Preceding gene: 15673476

Following gene: 15673474

Centisome position: 64.53

GC content: 35.27

Gene sequence:

>1548_bases
ATGAATAATTGGTGGAAAAAAGCAGTCATTTATCAAATTTATCCCCGGTCATTTAAGGATTCAAATGATGACGGAATTGG
TGACATCAATGGAATAATAGAGAAATTAACTTATCTTGAAAAACTAGGAGTGGATGGTATTTGGCTATCTCCGATTTATC
AATCCCCGATGGTTGATAATGGTTATGACATTAGTGATTACTATAAAATTGACCCACTTTTTGGAACAATGGCTGATTTT
GAAGCGCTCATAGAAAAAGCAAAGCAACTTAATATTCGTGTCATTATGGACTTGGTTGTCAATCATACTTCTGACCAACA
TTTGTGGTTTAAAGAATCCAAAAAATCTAAAAATAATCCGAGAAGAGATTTTTATATTTGGCGGGATCAACCGATTGGAG
AATTTAAAAATTGGACTTATGACTCAAGCACTCAACAATATTATTTTCATCTTTTTAGTCCACAGCAGCCTGACTTGAAT
TGGGAAAATGAAGAAGTGCGTAAGGAAATTCATAAGATGATGAATTTTTGGTTGGCTAAGGGAATTTCTGGTTTTAGATT
AGATGTCATTGATTTGATTGGAAAAAAACCAGAACAAGAAATCACGGTTAATGGTCCAAAACTGCATGATTACCTAAAAG
AGATGAATTTAGCAACTTTTGGTAAAAAGGACTATCTCACTGTTGGTGAAGCTTGGTCAAGTTCACCAGAATTAGCAAAG
TTATATAGTGGCCCCAATCGTCATGAACTTTCAATGGTTTTTGGCTTCTGGCATCTATTGACATCAGCAGGAAACGGGGA
CAAATGGAAAAAACTCCCCTTAAATGTTCCAAAGCTAAAAGAAGCAATGACCGCTTGGCAGAAATTGACGCCAAATGAAG
CATGGAATTCTCTTTTTCTAGGCAATCATGATTTGCCACGCATTGTCTCTTTTTGGGGAGATGAGGGAACATACAGAGAA
AAATCAGCCAAAGCTTTTGCAATTCTCTTTCATTTGATGCGTGGCACTTCTTTTATTTATCAAGGCGAAGAATTAGGAAT
GACCAATTTTCCTTTTGAAAATCTGTCAGCAATAAATGACGTAGAATCACATGAATATTTTACTGACAGAAAAAAAGAAG
GACAGTCAGAAGAAGAAATTATCAAAGTTTTGCGAGAAATGAGTCGTGATAATGCTAGGACGCCAATGCAATGGACCAGT
GATGAGAAAGCTGGTTTTACAAAAGGGAAAGCTTGGCTTTCTATCAATCCTAATACTAAGATAATAAATGCTGACCAAGC
TGTCAGTGATTCTAACTCTGTATTTTATACTTATCAAAAGTTAATCAAACTTCGTCACCAAGAAAATTGGCTGATAGAAG
GAGATTTTGAATTACTTGAAAGTGCTGACGAAATCTTCGCATACTTGAGAAAAACGACAACAAGAACTTTTCTGGTGGTC
GCCAACTTATCAAATTCAAGTCAACGTTTTGAAAGTTCTTTTGTCAAAAAAAATGAAATCATCAGTAATGACAGCTTTCC
AGATTTACTGACAGACATAGAAATTTAA

Upstream 100 bases:

>100_bases
TCGATTTGGGCTGACAATGCTGCAGCTAAGTCTGTCAGTGAAATTTTAGACGATCTTAGCAAGGTACTTCCGGTATTTAT
GAAAATTTATGGAGGAAATG

Downstream 100 bases:

>100_bases
CCTTGGCAAGCTTTTGCTTTAGAAATAAAAAATCTTGATTAATAAATTTTATTGGAGGATTTTATGAAAAAATCGAAAAA
ATTTTTTATTAGAATATGCC

Product: alpha 1-6-glucosidase

Products: NA

Alternate protein names: Dextran glucosidase; Exo-1,6-alpha-glucosidase; Glucodextranase [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MNNWWKKAVIYQIYPRSFKDSNDDGIGDINGIIEKLTYLEKLGVDGIWLSPIYQSPMVDNGYDISDYYKIDPLFGTMADF
EALIEKAKQLNIRVIMDLVVNHTSDQHLWFKESKKSKNNPRRDFYIWRDQPIGEFKNWTYDSSTQQYYFHLFSPQQPDLN
WENEEVRKEIHKMMNFWLAKGISGFRLDVIDLIGKKPEQEITVNGPKLHDYLKEMNLATFGKKDYLTVGEAWSSSPELAK
LYSGPNRHELSMVFGFWHLLTSAGNGDKWKKLPLNVPKLKEAMTAWQKLTPNEAWNSLFLGNHDLPRIVSFWGDEGTYRE
KSAKAFAILFHLMRGTSFIYQGEELGMTNFPFENLSAINDVESHEYFTDRKKEGQSEEEIIKVLREMSRDNARTPMQWTS
DEKAGFTKGKAWLSINPNTKIINADQAVSDSNSVFYTYQKLIKLRHQENWLIEGDFELLESADEIFAYLRKTTTRTFLVV
ANLSNSSQRFESSFVKKNEIISNDSFPDLLTDIEI

Sequences:

>Translated_515_residues
MNNWWKKAVIYQIYPRSFKDSNDDGIGDINGIIEKLTYLEKLGVDGIWLSPIYQSPMVDNGYDISDYYKIDPLFGTMADF
EALIEKAKQLNIRVIMDLVVNHTSDQHLWFKESKKSKNNPRRDFYIWRDQPIGEFKNWTYDSSTQQYYFHLFSPQQPDLN
WENEEVRKEIHKMMNFWLAKGISGFRLDVIDLIGKKPEQEITVNGPKLHDYLKEMNLATFGKKDYLTVGEAWSSSPELAK
LYSGPNRHELSMVFGFWHLLTSAGNGDKWKKLPLNVPKLKEAMTAWQKLTPNEAWNSLFLGNHDLPRIVSFWGDEGTYRE
KSAKAFAILFHLMRGTSFIYQGEELGMTNFPFENLSAINDVESHEYFTDRKKEGQSEEEIIKVLREMSRDNARTPMQWTS
DEKAGFTKGKAWLSINPNTKIINADQAVSDSNSVFYTYQKLIKLRHQENWLIEGDFELLESADEIFAYLRKTTTRTFLVV
ANLSNSSQRFESSFVKKNEIISNDSFPDLLTDIEI
>Mature_515_residues
MNNWWKKAVIYQIYPRSFKDSNDDGIGDINGIIEKLTYLEKLGVDGIWLSPIYQSPMVDNGYDISDYYKIDPLFGTMADF
EALIEKAKQLNIRVIMDLVVNHTSDQHLWFKESKKSKNNPRRDFYIWRDQPIGEFKNWTYDSSTQQYYFHLFSPQQPDLN
WENEEVRKEIHKMMNFWLAKGISGFRLDVIDLIGKKPEQEITVNGPKLHDYLKEMNLATFGKKDYLTVGEAWSSSPELAK
LYSGPNRHELSMVFGFWHLLTSAGNGDKWKKLPLNVPKLKEAMTAWQKLTPNEAWNSLFLGNHDLPRIVSFWGDEGTYRE
KSAKAFAILFHLMRGTSFIYQGEELGMTNFPFENLSAINDVESHEYFTDRKKEGQSEEEIIKVLREMSRDNARTPMQWTS
DEKAGFTKGKAWLSINPNTKIINADQAVSDSNSVFYTYQKLIKLRHQENWLIEGDFELLESADEIFAYLRKTTTRTFLVV
ANLSNSSQRFESSFVKKNEIISNDSFPDLLTDIEI

Specific function: The physiological substrates may be short isomaltosaccharides [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=531, Percent_Identity=29.7551789077213, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI61744475, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI65506891, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI61744479, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI61744477, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI61744483, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI61744481, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1790687, Length=518, Percent_Identity=44.5945945945946, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1786604, Length=182, Percent_Identity=31.8681318681319, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565753, Length=537, Percent_Identity=23.8361266294227, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25147709, Length=510, Percent_Identity=22.7450980392157, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321726, Length=538, Percent_Identity=37.1747211895911, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6322245, Length=536, Percent_Identity=36.9402985074627, Blast_Score=339, Evalue=8e-94,
Organism=Saccharomyces cerevisiae, GI6324416, Length=539, Percent_Identity=37.1057513914657, Blast_Score=336, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6322241, Length=539, Percent_Identity=37.1057513914657, Blast_Score=332, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6322021, Length=539, Percent_Identity=37.1057513914657, Blast_Score=332, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6321731, Length=537, Percent_Identity=35.3817504655494, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6319776, Length=537, Percent_Identity=35.3817504655494, Blast_Score=310, Evalue=3e-85,
Organism=Drosophila melanogaster, GI221330053, Length=534, Percent_Identity=32.5842696629214, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI45549022, Length=536, Percent_Identity=33.3955223880597, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24583745, Length=523, Percent_Identity=35.1816443594646, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24586593, Length=561, Percent_Identity=31.9073083778966, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24583749, Length=535, Percent_Identity=33.2710280373832, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24583747, Length=535, Percent_Identity=33.4579439252336, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24586599, Length=547, Percent_Identity=31.0786106032907, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24586589, Length=554, Percent_Identity=30.8664259927798, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24586597, Length=532, Percent_Identity=30.6390977443609, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24586591, Length=514, Percent_Identity=32.4902723735409, Blast_Score=242, Evalue=5e-64,
Organism=Drosophila melanogaster, GI24586587, Length=558, Percent_Identity=29.3906810035842, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI281360393, Length=508, Percent_Identity=28.3464566929134, Blast_Score=183, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.70 [H]

Molecular weight: Translated: 59974; Mature: 59974

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNWWKKAVIYQIYPRSFKDSNDDGIGDINGIIEKLTYLEKLGVDGIWLSPIYQSPMVDN
CCCHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHCCCCCCC
GYDISDYYKIDPLFGTMADFEALIEKAKQLNIRVIMDLVVNHTSDQHLWFKESKKSKNNP
CCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHEEHHHHCCCCCCCEEEEHHHCCCCCC
RRDFYIWRDQPIGEFKNWTYDSSTQQYYFHLFSPQQPDLNWENEEVRKEIHKMMNFWLAK
CCCEEEECCCCCCHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHC
GISGFRLDVIDLIGKKPEQEITVNGPKLHDYLKEMNLATFGKKDYLTVGEAWSSSPELAK
CCCCCEEHHHHHHCCCCCCCEEECCHHHHHHHHHCCHHHCCCCCCEEECCCCCCCCCHHH
LYSGPNRHELSMVFGFWHLLTSAGNGDKWKKLPLNVPKLKEAMTAWQKLTPNEAWNSLFL
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCEEEC
GNHDLPRIVSFWGDEGTYREKSAKAFAILFHLMRGTSFIYQGEELGMTNFPFENLSAIND
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHH
VESHEYFTDRKKEGQSEEEIIKVLREMSRDNARTPMQWTSDEKAGFTKGKAWLSINPNTK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCE
IINADQAVSDSNSVFYTYQKLIKLRHQENWLIEGDFELLESADEIFAYLRKTTTRTFLVV
EEECCCCCCCCCCEEHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEEE
ANLSNSSQRFESSFVKKNEIISNDSFPDLLTDIEI
EECCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure
MNNWWKKAVIYQIYPRSFKDSNDDGIGDINGIIEKLTYLEKLGVDGIWLSPIYQSPMVDN
CCCHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHCCCCCCC
GYDISDYYKIDPLFGTMADFEALIEKAKQLNIRVIMDLVVNHTSDQHLWFKESKKSKNNP
CCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHEEHHHHCCCCCCCEEEEHHHCCCCCC
RRDFYIWRDQPIGEFKNWTYDSSTQQYYFHLFSPQQPDLNWENEEVRKEIHKMMNFWLAK
CCCEEEECCCCCCHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHC
GISGFRLDVIDLIGKKPEQEITVNGPKLHDYLKEMNLATFGKKDYLTVGEAWSSSPELAK
CCCCCEEHHHHHHCCCCCCCEEECCHHHHHHHHHCCHHHCCCCCCEEECCCCCCCCCHHH
LYSGPNRHELSMVFGFWHLLTSAGNGDKWKKLPLNVPKLKEAMTAWQKLTPNEAWNSLFL
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCEEEC
GNHDLPRIVSFWGDEGTYREKSAKAFAILFHLMRGTSFIYQGEELGMTNFPFENLSAIND
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHH
VESHEYFTDRKKEGQSEEEIIKVLREMSRDNARTPMQWTSDEKAGFTKGKAWLSINPNTK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCE
IINADQAVSDSNSVFYTYQKLIKLRHQENWLIEGDFELLESADEIFAYLRKTTTRTFLVV
EEECCCCCCCCCCEEHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEEE
ANLSNSSQRFESSFVKKNEIISNDSFPDLLTDIEI
EECCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916; 8566758; 8021229; 9466257; 9383201 [H]