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The map label for this gene is coaE

Identifier: 15672647

GI number: 15672647

Start: 659913

End: 660572

Strand: Direct

Name: coaE

Synonym: L59930

Alternate gene names: 15672647

Gene position: 659913-660572 (Clockwise)

Preceding gene: 15672646

Following gene: 15672648

Centisome position: 27.9

GC content: 33.18

Gene sequence:

>660_bases
ATGAAAATGGTAATTGGATTGACAGGCGGAATTGCGAGTGGGAAATCAACGGTGGTTGATTTTTTGATTTCTGAGGGTTA
TCAAGTGATTGATGCTGACAAAGTTGTCCGTCAATTACAAGAACCTGGCGGAAAACTTTACAAGGCAATAGTAGAAACTT
ACGGTTTAGATTTTATTGCTGACAATGGACAGTTAAATCGTGAAAAATTAGGAGCTTTAGTTTTTTCTGATTCAAAAGAG
CGCGAGAAATTATCAAACTTACAAGATGAAATTATTCGTACAGAATTATATGATAGACGTGATGACTTATTAAAAAAAAT
GACTGACAAGTCTGTCAGTAAAAATTTTGATTCAAAGAGTCAAGGAAAAAATCTGTCAGTAAATAAGCCAATATTTATGG
ATATTCCGTTATTAATTGAATACAATTATACCGGATTTGATGAAATATGGTTGGTCAGCTTACCTGAAAAAATACAATTA
GAAAGACTGATGGCAAGAAATAAGTTTACGGAAGAAGAAGCTAAAAAACGAATTTCTTCACAAATGCCATTGTCAGAAAA
ACAAAAAGTCGCTGATGTCATTCTGGATAATTTTGGAACGATTGAAGCACTAAAAAAACAAATCCAGCGAGAACTAGCTA
GGATAGAAGAACAGAAATAG

Upstream 100 bases:

>100_bases
AGTTTTACTGACAGACTTTTTTTACGAAAAAATTAATCATAATAGTTAAAAACTATTGTTTTTAGTTTAAGAAAGTTAAA
TTTTATGCTAAAATAGATGA

Downstream 100 bases:

>100_bases
AGGTGAATCGCACGAAAACAGTTAATTGGAAAAGGAATTTATTTATAACATGGATTGGCTGCTTTTTTGTAGGTTCATCA
TTTTCACTCGTCATGCCCTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKMVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIADNGQLNREKLGALVFSDSKE
REKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKSQGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQL
ERLMARNKFTEEEAKKRISSQMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK

Sequences:

>Translated_219_residues
MKMVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIADNGQLNREKLGALVFSDSKE
REKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKSQGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQL
ERLMARNKFTEEEAKKRISSQMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK
>Mature_219_residues
MKMVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIADNGQLNREKLGALVFSDSKE
REKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKSQGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQL
ERLMARNKFTEEEAKKRISSQMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=208, Percent_Identity=33.1730769230769, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI191252795, Length=208, Percent_Identity=33.1730769230769, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI110227607, Length=216, Percent_Identity=27.7777777777778, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI110227605, Length=216, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110227603, Length=216, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110227601, Length=216, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI205277394, Length=216, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1786292, Length=211, Percent_Identity=27.9620853080569, Blast_Score=96, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554944, Length=222, Percent_Identity=31.0810810810811, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25143409, Length=211, Percent_Identity=31.2796208530806, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320402, Length=224, Percent_Identity=34.375, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24658602, Length=211, Percent_Identity=34.5971563981043, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644728, Length=205, Percent_Identity=32.6829268292683, Blast_Score=114, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 25025; Mature: 25025

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIA
CEEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
DNGQLNREKLGALVFSDSKEREKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKS
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQLERLMARNKFTEEEAKKRISS
CCCCCCCCCCEEEECCEEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHH
QMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIA
CEEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
DNGQLNREKLGALVFSDSKEREKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKS
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQLERLMARNKFTEEEAKKRISS
CCCCCCCCCCEEEECCEEEEECCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHH
QMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]