Click here to switch to the map view.

The map label for this gene is hly

Identifier: 15672479

GI number: 15672479

Start: 497815

End: 498468

Strand: Reverse

Name: hly

Synonym: L97827

Alternate gene names: 15672479

Gene position: 498468-497815 (Counterclockwise)

Preceding gene: 15672485

Following gene: 15672477

Centisome position: 21.07

GC content: 37.92

Gene sequence:

>654_bases
ATGGAAGAAACACAAGGTTCAAAAACCTATCAGATTCTCAATGAGATTTTCAATGCAGTTACTCATGGAGCAGGAACTGG
TCTAGCAATTGCAGCATTAGTTCTCCTTGTCATTAAAGGTGCCGCATCTGGTTCTGCACTTGAAGTGGTTGCTTTTACAA
TCTATGGAGCTTCGTTAGTCATTCTTTTTCTATGTTCAACTTTAGCGCACGGTTTACATTTTACTAAAGCAGTCAAAGTC
TTTCGAGTTTTTGACCACAACGGAATTTTCTTTTTGATTGCTGGAACTTATACCCCTTACTGTTTAGTTGCTTTAAACAA
TTGGCTAGGTTGGATTGTCCTAGCAGTTATTTGGATATGTTCTATTTTAGGGATTGTTTTAACATCAATATACTTACCAA
AATGGGGTAAAACACCAAAATTATCAACCGTTTTATACGTCGTTCTTGGTTGGATGATTTTAATTGTCATTTATCCTTTA
TGGAATGCCCTGGATCCCGTAGGTTTCTGGCTTTTAGTCGCTGGTGGCGTTGTTTATTCTGTTGGAGCACTCATCTATCA
CTTTAAATTTCCTTTTGCCCATGTGGTATGGCACCTCTTTGTTTTACTGGCTGCAATGCTCATGTTCTTCTCTGTTTACC
TTTATGTGGGATAA

Upstream 100 bases:

>100_bases
TGGAAAGAGCAAAAAAGGTTGATAATATTATTTTTTTGATTCCAAAAACAAATTAAAAATTGCTCAAAAGCTGAATAAAT
CAATAAATTGGAGAGACCAA

Downstream 100 bases:

>100_bases
GATAAAAAACCGTTCGGATGAACGGGTTTTTTATTTATAAATACCAGCTATAACATACCCTTCTAGCCTTTTTTGTAAAA
TCTCCGATTCTTCCACATAA

Product: hemolysin like protein

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MEETQGSKTYQILNEIFNAVTHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLVILFLCSTLAHGLHFTKAVKV
FRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWICSILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPL
WNALDPVGFWLLVAGGVVYSVGALIYHFKFPFAHVVWHLFVLLAAMLMFFSVYLYVG

Sequences:

>Translated_217_residues
MEETQGSKTYQILNEIFNAVTHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLVILFLCSTLAHGLHFTKAVKV
FRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWICSILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPL
WNALDPVGFWLLVAGGVVYSVGALIYHFKFPFAHVVWHLFVLLAAMLMFFSVYLYVG
>Mature_217_residues
MEETQGSKTYQILNEIFNAVTHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLVILFLCSTLAHGLHFTKAVKV
FRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWICSILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPL
WNALDPVGFWLLVAGGVVYSVGALIYHFKFPFAHVVWHLFVLLAAMLMFFSVYLYVG

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=186, Percent_Identity=31.1827956989247, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI154759277, Length=206, Percent_Identity=28.6407766990291, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789266, Length=213, Percent_Identity=38.9671361502347, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71996356, Length=219, Percent_Identity=31.5068493150685, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23865; Mature: 23865

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEETQGSKTYQILNEIFNAVTHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLV
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILFLCSTLAHGLHFTKAVKVFRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWIC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPLWNALDPVGFWLLVAGGVVYS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGALIYHFKFPFAHVVWHLFVLLAAMLMFFSVYLYVG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEETQGSKTYQILNEIFNAVTHGAGTGLAIAALVLLVIKGAASGSALEVVAFTIYGASLV
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILFLCSTLAHGLHFTKAVKVFRVFDHNGIFFLIAGTYTPYCLVALNNWLGWIVLAVIWIC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SILGIVLTSIYLPKWGKTPKLSTVLYVVLGWMILIVIYPLWNALDPVGFWLLVAGGVVYS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGALIYHFKFPFAHVVWHLFVLLAAMLMFFSVYLYVG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]