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The map label for this gene is ps201

Identifier: 15672485

GI number: 15672485

Start: 502723

End: 503871

Strand: Reverse

Name: ps201

Synonym: L102735

Alternate gene names: 15672485

Gene position: 503871-502723 (Counterclockwise)

Preceding gene: 15672486

Following gene: 15672479

Centisome position: 21.3

GC content: 32.29

Gene sequence:

>1149_bases
ATGTGGATAGAAAATTTACCAAATGGAAAATACAAATATTTTGAAAGATACCGTGATCCACTAACAGAGAAACTAAAAAA
AGTATCTGTTACACTTGATAAAAAAACACCCAGAGCACAGAAAGTTGCACAGGCTGAACTCCTTGAAAAAATAGAATCTA
AAATTAATAACAGTTCTACTTCCAATGCTAAATTTACAGATATAGCTGAAGAATGGTGGAGCTTTTATAAAAAATCCATA
AAACAATCCTCCATTAGTGCTCTTCAAAGTTCTTTTAATTTTATAATTGATTATTTTGACAAGGAAATTAAAATATCAAA
TGTTACATCTAAAGTTATACAAAAATTTATAAATGATGCAGACTGTCCTCGTAGCAAGTTAGAACGCTCAAAATCAACCC
TAAATCTTATATTTGATTATGCTGTTGATTTAGAATACATTGAATATAATCCAGCACGAAAAGCTAAACTTCCCAAAAAG
ATTCAGACGGTAAAGGATTTAGAGAAAATACAAAATAAATACCTTGAACAAAACGAATTAAAAGCCCTACTTTCAGAACT
GTACAGCAGGCCAAACACTCGTAGATTGGCTTTACTTGCTGAGTTCATGTCATTGAATGGATGTCGAATGGGAGAGGCGA
TAGCTTTAAAAAAAGAAAATTATAAAAGAAGTGAACGAAAAATAGACATTCACGGTACTTTAGATAAAACGGTTGGTTAT
TCAAAAGGAGTCAAAACAACTCCTAAAACCGCATCTAGTTTTAGAACAGTAGATTTGAGTGACCGAGAAATAGAGATATT
AGACGAAATAATTGAACAAAATAATTTGTCCAAATCTGTAATAAACGATTATAACGAAATGGGCTATATTTTCGTTTCTA
AGCGTGGTATTCCGTTGCAGACAAACTCCTTTAACCTTGCAATTAAAAGAGCAAATTCTCGCCTTAAATCGCCAATAAAC
AAGAATCTATCAAGCCATATCTTCCGTCATACATTAATAAGCTATCTGGCAGAAAACAATGTTCCCCTCAAAGCAATTGT
CGATAGAGTAGGGCATAAGGATGGCGGTAAAACAACAACTGCTATATACACTCACGTTACCGAAAATATGAAGTCTTCGA
TAATAGATATACTAAATAAAAAGAACTGA

Upstream 100 bases:

>100_bases
TGGCGACGAGGGGCGGCTTAAATCTCAAACATAGTAGAAAAGCTTTTTAAAAAGCCCTTTTACTGTACTCAATTTTAGCA
AGAAAGTGAGTAAAAATCAA

Downstream 100 bases:

>100_bases
GCCTTTGCCAGTTTTTTTATTTTGTGCCCCTTTTGTGCCCCTTTTTCATTTTATAAAAAAACAAAAAGTACCACGAACTA
GCGTGATACTTGATGTTTTA

Product: integrase

Products: NA

Alternate protein names: Int-TnX

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MWIENLPNGKYKYFERYRDPLTEKLKKVSVTLDKKTPRAQKVAQAELLEKIESKINNSSTSNAKFTDIAEEWWSFYKKSI
KQSSISALQSSFNFIIDYFDKEIKISNVTSKVIQKFINDADCPRSKLERSKSTLNLIFDYAVDLEYIEYNPARKAKLPKK
IQTVKDLEKIQNKYLEQNELKALLSELYSRPNTRRLALLAEFMSLNGCRMGEAIALKKENYKRSERKIDIHGTLDKTVGY
SKGVKTTPKTASSFRTVDLSDREIEILDEIIEQNNLSKSVINDYNEMGYIFVSKRGIPLQTNSFNLAIKRANSRLKSPIN
KNLSSHIFRHTLISYLAENNVPLKAIVDRVGHKDGGKTTTAIYTHVTENMKSSIIDILNKKN

Sequences:

>Translated_382_residues
MWIENLPNGKYKYFERYRDPLTEKLKKVSVTLDKKTPRAQKVAQAELLEKIESKINNSSTSNAKFTDIAEEWWSFYKKSI
KQSSISALQSSFNFIIDYFDKEIKISNVTSKVIQKFINDADCPRSKLERSKSTLNLIFDYAVDLEYIEYNPARKAKLPKK
IQTVKDLEKIQNKYLEQNELKALLSELYSRPNTRRLALLAEFMSLNGCRMGEAIALKKENYKRSERKIDIHGTLDKTVGY
SKGVKTTPKTASSFRTVDLSDREIEILDEIIEQNNLSKSVINDYNEMGYIFVSKRGIPLQTNSFNLAIKRANSRLKSPIN
KNLSSHIFRHTLISYLAENNVPLKAIVDRVGHKDGGKTTTAIYTHVTENMKSSIIDILNKKN
>Mature_382_residues
MWIENLPNGKYKYFERYRDPLTEKLKKVSVTLDKKTPRAQKVAQAELLEKIESKINNSSTSNAKFTDIAEEWWSFYKKSI
KQSSISALQSSFNFIIDYFDKEIKISNVTSKVIQKFINDADCPRSKLERSKSTLNLIFDYAVDLEYIEYNPARKAKLPKK
IQTVKDLEKIQNKYLEQNELKALLSELYSRPNTRRLALLAEFMSLNGCRMGEAIALKKENYKRSERKIDIHGTLDKTVGY
SKGVKTTPKTASSFRTVDLSDREIEILDEIIEQNNLSKSVINDYNEMGYIFVSKRGIPLQTNSFNLAIKRANSRLKSPIN
KNLSSHIFRHTLISYLAENNVPLKAIVDRVGHKDGGKTTTAIYTHVTENMKSSIIDILNKKN

Specific function: Site-Specific Tyrosine Recombinase, Which Acts By Catalyzing The Cutting And Rejoining Of The Recombining DNA Molecules. Binds Cooperatively To Specific DNA Consensus Sequences That Are Separated From Xerc Binding Sites By A Short Central Region, Forming

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): P2IN_LACLA (Q9CI63)

Other databases:

- EMBL:   AF320916
- EMBL:   AE005176
- PIR:   G86687
- RefSeq:   NP_266659.1
- ProteinModelPortal:   Q9CI63
- GeneID:   1114122
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L102735
- NMPDR:   fig|272623.1.peg.518
- HOGENOM:   HBG693086
- OMA:   DINGTIH
- ProtClustDB:   CLSK697262
- BioCyc:   LLAC272623:L102735-MONOMER
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 43959; Mature: 43959

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: ACT_SITE 363-363

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWIENLPNGKYKYFERYRDPLTEKLKKVSVTLDKKTPRAQKVAQAELLEKIESKINNSST
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
SNAKFTDIAEEWWSFYKKSIKQSSISALQSSFNFIIDYFDKEIKISNVTSKVIQKFINDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCC
DCPRSKLERSKSTLNLIFDYAVDLEYIEYNPARKAKLPKKIQTVKDLEKIQNKYLEQNEL
CCCHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHH
KALLSELYSRPNTRRLALLAEFMSLNGCRMGEAIALKKENYKRSERKIDIHGTLDKTVGY
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHEECHHHHHHHHCEEEEECCHHHHCCC
SKGVKTTPKTASSFRTVDLSDREIEILDEIIEQNNLSKSVINDYNEMGYIFVSKRGIPLQ
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCEE
TNSFNLAIKRANSRLKSPINKNLSSHIFRHTLISYLAENNVPLKAIVDRVGHKDGGKTTT
CCCCEEEEEHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHH
AIYTHVTENMKSSIIDILNKKN
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWIENLPNGKYKYFERYRDPLTEKLKKVSVTLDKKTPRAQKVAQAELLEKIESKINNSST
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
SNAKFTDIAEEWWSFYKKSIKQSSISALQSSFNFIIDYFDKEIKISNVTSKVIQKFINDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCC
DCPRSKLERSKSTLNLIFDYAVDLEYIEYNPARKAKLPKKIQTVKDLEKIQNKYLEQNEL
CCCHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHH
KALLSELYSRPNTRRLALLAEFMSLNGCRMGEAIALKKENYKRSERKIDIHGTLDKTVGY
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHEECHHHHHHHHCEEEEECCHHHHCCC
SKGVKTTPKTASSFRTVDLSDREIEILDEIIEQNNLSKSVINDYNEMGYIFVSKRGIPLQ
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCEE
TNSFNLAIKRANSRLKSPINKNLSSHIFRHTLISYLAENNVPLKAIVDRVGHKDGGKTTT
CCCCEEEEEHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHH
AIYTHVTENMKSSIIDILNKKN
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10532372; 11337471