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The map label for this gene is dukA

Identifier: 15672477

GI number: 15672477

Start: 493469

End: 494122

Strand: Reverse

Name: dukA

Synonym: L93481

Alternate gene names: NA

Gene position: 494122-493469 (Counterclockwise)

Preceding gene: 15672479

Following gene: 15672476

Centisome position: 20.89

GC content: 31.5

Gene sequence:

>654_bases
ATGACAGTGCTAGTATTAGCTGGAACAATCGGAGCAGGAAAAAGCTCTTTAACTGAGATGTTGGCGGAGGAATTGAAAAC
ACAAGCTTTTTATGAGAGTGTTGACGATAATAAAGTTTTGCCATTATTCTATGAGAACCCTCAAAAATATGCCTTCTTAT
TACAAATATACTTTTTAAATAAGCGATTTGATTCAATCAAAAGAGCCTTGTCTGATAATAATAATGTATTAGACCGCTCG
ATTTATGAAGATAGTCTGCTTTTTCATTTGAACGCCGATTTAGGACGAGCAGATGAAACGGAAGTCGAGGTTTATGATGA
CTTACTTAACAATATGTTGGAAGAAATTGATAGTTTATCTTTCAAAAAAAGGCCTGATTTACTCATTCATGTCAAAGTTT
CTTTTGATAAAATGCTAGAAAGAATCAAAAAAAGAGGACGTCAATTTGAACAATTGGAATACGATCCAAGTTTATATGAC
TACTATAAAGAATTAAATAGCAGATATGATACTTGGTTTGAAGACTTTGATATTTGTCCCAAAATCCAAATTGGTGGCGA
TAAATATGATTTTGTGGAGGACGAACAATCAAAAATTCATGTTTTGCAACAAATCAAAGAAAAATTAAAAGAAATTGAAG
GAGAAAATAATTAA

Upstream 100 bases:

>100_bases
GAGAACATTTTTTTGCACTATAATGAGCAAGCCTTGTTTATTTATTACTAATTTTTAATTAAACAATCACTAAAACTAAA
AATAGAATGGTAAAGGTGTA

Downstream 100 bases:

>100_bases
TGAATGTCACCGTCTTTCTTTCTTCAAGAGATGGAAAAAATCCAATCTATAAAGATACAAGCGAAAAATTAGGAATATTA
CTTGCTAAATAAGGCCATAC

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTVLVLAGTIGAGKSSLTEMLAEELKTQAFYESVDDNKVLPLFYENPQKYAFLLQIYFLNKRFDSIKRALSDNNNVLDRS
IYEDSLLFHLNADLGRADETEVEVYDDLLNNMLEEIDSLSFKKRPDLLIHVKVSFDKMLERIKKRGRQFEQLEYDPSLYD
YYKELNSRYDTWFEDFDICPKIQIGGDKYDFVEDEQSKIHVLQQIKEKLKEIEGENN

Sequences:

>Translated_217_residues
MTVLVLAGTIGAGKSSLTEMLAEELKTQAFYESVDDNKVLPLFYENPQKYAFLLQIYFLNKRFDSIKRALSDNNNVLDRS
IYEDSLLFHLNADLGRADETEVEVYDDLLNNMLEEIDSLSFKKRPDLLIHVKVSFDKMLERIKKRGRQFEQLEYDPSLYD
YYKELNSRYDTWFEDFDICPKIQIGGDKYDFVEDEQSKIHVLQQIKEKLKEIEGENN
>Mature_216_residues
TVLVLAGTIGAGKSSLTEMLAEELKTQAFYESVDDNKVLPLFYENPQKYAFLLQIYFLNKRFDSIKRALSDNNNVLDRSI
YEDSLLFHLNADLGRADETEVEVYDDLLNNMLEEIDSLSFKKRPDLLIHVKVSFDKMLERIKKRGRQFEQLEYDPSLYDY
YKELNSRYDTWFEDFDICPKIQIGGDKYDFVEDEQSKIHVLQQIKEKLKEIEGENN

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25568; Mature: 25437

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVLAGTIGAGKSSLTEMLAEELKTQAFYESVDDNKVLPLFYENPQKYAFLLQIYFLN
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
KRFDSIKRALSDNNNVLDRSIYEDSLLFHLNADLGRADETEVEVYDDLLNNMLEEIDSLS
HHHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
FKKRPDLLIHVKVSFDKMLERIKKRGRQFEQLEYDPSLYDYYKELNSRYDTWFEDFDICP
CCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
KIQIGGDKYDFVEDEQSKIHVLQQIKEKLKEIEGENN
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVLVLAGTIGAGKSSLTEMLAEELKTQAFYESVDDNKVLPLFYENPQKYAFLLQIYFLN
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHH
KRFDSIKRALSDNNNVLDRSIYEDSLLFHLNADLGRADETEVEVYDDLLNNMLEEIDSLS
HHHHHHHHHHCCCCCCHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
FKKRPDLLIHVKVSFDKMLERIKKRGRQFEQLEYDPSLYDYYKELNSRYDTWFEDFDICP
CCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
KIQIGGDKYDFVEDEQSKIHVLQQIKEKLKEIEGENN
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]