Click here to switch to the map view.

The map label for this gene is yebA

Identifier: 15672388

GI number: 15672388

Start: 410036

End: 411025

Strand: Direct

Name: yebA

Synonym: L10014

Alternate gene names: NA

Gene position: 410036-411025 (Clockwise)

Preceding gene: 15672387

Following gene: 15672389

Centisome position: 17.33

GC content: 33.43

Gene sequence:

>990_bases
ATGAATATCTCTGAGAAAAAAATGTCAATCAAAGTGCCAGGAAAACTTTTTTTTGCGGGAGAATATTCGGTCACAAAAGA
AGGAAACCTCGCCCTTATCACAACAATTGAAACAAATTTTGAAGTAAGAATTTCAGCTACTACAGGGAAATCAATTTTCA
AAACAAATGTTGGACTATCTGATTTTGAATTTTCTTTGTCTAAAATTGAATTTACTAAAGAAAATCCGTGGAATTTTGCA
CTGACAGCTTTAAAAAATACTTTGTCAGCTGCTGACAGCTTTGAAAAAAAATCTGTCAGTAAAATTTTATCATCATCTCC
AGAAATTTCTCTTGAGATTGTCAGTGATTTAGGCTTTGGTGAAAATAAAAAAGGCTACGGCTCAAGTGCTTCAGTCGTTT
GTGGTCTAGTTAATGCAGTCAATCAGTTTTTTGATTTCCAGTTGTCACTTGAAAAACGTTTTGAAATTGCCGCAAAAACA
CATTTTGAAGTTCAAGGCTCAGGTTCAATGGGCGATATTGCTGCTATTATGTATGGTGGTTCTGTTTTTTATCAAAATCA
TAAGCGAGTCATACCTCTCGAAATTCCTTGGGCAACTTATGTGGTTCAAACAGGAAAAGCGGCAAAAACGAGTGAAAAAA
TAAAAATAAAGCTTTCTGATGAATTTTATCAAGCTTCAAATGAGCTGGTCATTGAATTGGCAACGGCGATTGACATTCAA
GATTTTGCTTTATTCAAAGAAAAGTTATCAGAAAATCAACTTTTGCTTTTGGAGAATATTCCAGAAGGTTATATGACTAA
AGAATTAGCTATTGCTTTAAACTTACTCAATAGCTATCCTGAATTTGCTGCTAAAATCTCTGGGGCCGGTTTTGGGGAGA
ATATTATTTTATTTGCTCAAAATACCCAAGCTATTGCTGAAGTCCAAAATAAATTATCGGAATATGGAATCAATCTTGAA
AAATTTAAGGTTGCTCAAAAAAATAACTGA

Upstream 100 bases:

>100_bases
AAAATTATTACTGACCACGCGACTGAAAAAGTTCTCTTAGCTAAATTACAAGCGGAATTTCCAGAATTAACATTTGATAT
CGCACGTGCTGGGGGCGCTT

Downstream 100 bases:

>100_bases
GATAAGTCTGCTAAAAAGCAGAGTTAGATTTTAATGAATTGAGAAATAACTGATGAAAACTGAAAAAGAAATCCATCAAC
ATCGCAAAGATGAACACTTA

Product: mevalonate kinase

Products: ADP; (R)-5-diphosphomevalonate

Alternate protein names: Mevalonate Kinase

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNISEKKMSIKVPGKLFFAGEYSVTKEGNLALITTIETNFEVRISATTGKSIFKTNVGLSDFEFSLSKIEFTKENPWNFA
LTALKNTLSAADSFEKKSVSKILSSSPEISLEIVSDLGFGENKKGYGSSASVVCGLVNAVNQFFDFQLSLEKRFEIAAKT
HFEVQGSGSMGDIAAIMYGGSVFYQNHKRVIPLEIPWATYVVQTGKAAKTSEKIKIKLSDEFYQASNELVIELATAIDIQ
DFALFKEKLSENQLLLLENIPEGYMTKELAIALNLLNSYPEFAAKISGAGFGENIILFAQNTQAIAEVQNKLSEYGINLE
KFKVAQKNN

Sequences:

>Translated_329_residues
MNISEKKMSIKVPGKLFFAGEYSVTKEGNLALITTIETNFEVRISATTGKSIFKTNVGLSDFEFSLSKIEFTKENPWNFA
LTALKNTLSAADSFEKKSVSKILSSSPEISLEIVSDLGFGENKKGYGSSASVVCGLVNAVNQFFDFQLSLEKRFEIAAKT
HFEVQGSGSMGDIAAIMYGGSVFYQNHKRVIPLEIPWATYVVQTGKAAKTSEKIKIKLSDEFYQASNELVIELATAIDIQ
DFALFKEKLSENQLLLLENIPEGYMTKELAIALNLLNSYPEFAAKISGAGFGENIILFAQNTQAIAEVQNKLSEYGINLE
KFKVAQKNN
>Mature_329_residues
MNISEKKMSIKVPGKLFFAGEYSVTKEGNLALITTIETNFEVRISATTGKSIFKTNVGLSDFEFSLSKIEFTKENPWNFA
LTALKNTLSAADSFEKKSVSKILSSSPEISLEIVSDLGFGENKKGYGSSASVVCGLVNAVNQFFDFQLSLEKRFEIAAKT
HFEVQGSGSMGDIAAIMYGGSVFYQNHKRVIPLEIPWATYVVQTGKAAKTSEKIKIKLSDEFYQASNELVIELATAIDIQ
DFALFKEKLSENQLLLLENIPEGYMTKELAIALNLLNSYPEFAAKISGAGFGENIILFAQNTQAIAEVQNKLSEYGINLE
KFKVAQKNN

Specific function: Unknown

COG id: COG1577

COG function: function code I; Mevalonate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.4.2

Molecular weight: Translated: 36267; Mature: 36267

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISEKKMSIKVPGKLFFAGEYSVTKEGNLALITTIETNFEVRISATTGKSIFKTNVGLS
CCCCCCEEEEECCCEEEEECCEEEECCCCEEEEEEEECCEEEEEEECCCCEEEEECCCCC
DFEFSLSKIEFTKENPWNFALTALKNTLSAADSFEKKSVSKILSSSPEISLEIVSDLGFG
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
ENKKGYGSSASVVCGLVNAVNQFFDFQLSLEKRFEIAAKTHFEVQGSGSMGDIAAIMYGG
CCCCCCCCCHHHHHHHHHHHHHHHEEEEEHHHHEEEEEEEEEEEECCCCCCCEEEEEECC
SVFYQNHKRVIPLEIPWATYVVQTGKAAKTSEKIKIKLSDEFYQASNELVIELATAIDIQ
EEEEECCCEEEEEECCCEEEEEECCCCCCCCCEEEEEECCHHHHCCCCEEEEEEHHCCHH
DFALFKEKLSENQLLLLENIPEGYMTKELAIALNLLNSYPEFAAKISGAGFGENIILFAQ
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEEEC
NTQAIAEVQNKLSEYGINLEKFKVAQKNN
CCHHHHHHHHHHHHHCCCHHHEEEECCCC
>Mature Secondary Structure
MNISEKKMSIKVPGKLFFAGEYSVTKEGNLALITTIETNFEVRISATTGKSIFKTNVGLS
CCCCCCEEEEECCCEEEEECCEEEECCCCEEEEEEEECCEEEEEEECCCCEEEEECCCCC
DFEFSLSKIEFTKENPWNFALTALKNTLSAADSFEKKSVSKILSSSPEISLEIVSDLGFG
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
ENKKGYGSSASVVCGLVNAVNQFFDFQLSLEKRFEIAAKTHFEVQGSGSMGDIAAIMYGG
CCCCCCCCCHHHHHHHHHHHHHHHEEEEEHHHHEEEEEEEEEEEECCCCCCCEEEEEECC
SVFYQNHKRVIPLEIPWATYVVQTGKAAKTSEKIKIKLSDEFYQASNELVIELATAIDIQ
EEEEECCCEEEEEECCCEEEEEECCCCCCCCCEEEEEECCHHHHCCCCEEEEEEHHCCHH
DFALFKEKLSENQLLLLENIPEGYMTKELAIALNLLNSYPEFAAKISGAGFGENIILFAQ
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEEEC
NTQAIAEVQNKLSEYGINLEKFKVAQKNN
CCHHHHHHHHHHHHHCCCHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; (R)-5-phosphomevalonate

Specific reaction: ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA