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The map label for this gene is pepN

Identifier: 15672287

GI number: 15672287

Start: 302381

End: 304921

Strand: Direct

Name: pepN

Synonym: L102360

Alternate gene names: 15672287

Gene position: 302381-304921 (Clockwise)

Preceding gene: 15672286

Following gene: 15672291

Centisome position: 12.78

GC content: 37.7

Gene sequence:

>2541_bases
ATGGCTGTAAAACGTTTAATTGAAACTTTTGTTCCGGAAAATTATAAGATTTTCCTCGATATTGACCGTAAAACCAAGAA
AATAAAAGGTCAAGTGGCAATTACTGGGGAAGCAAAAGATAGTGTTATTGCCTTTCATGCCAAAGGTTTACACTTTAGTA
AAGTTCGTGCTTTTAGTGTCGACACAAACTTCATTGAAAATGAAGAAGATGAAGAAATCGTTGTTAAAATTGGTGAAACA
GGGCGCGTGACTGTTTCATTTGAATATGAAGCTGAATTGACTGACAACATGATGGGAATTTACCCTTCATACTATGAAGT
CAATGGCGAAAAGAAAATGCTCATTGGTACACAATTTGAAAGCCATTTTGCTCGTCAAGCCTTTCCTTCTATTGATGAAC
CAGAAGCAAAAGCAACCTTCGATTTGTCAGTAAAATTTGATGAAGAAGAAGGCGACATCATTGTTTCAAACATGCCAGAA
CTCTTGAATATTAACGGAATTCACGTTTTTGAACGTACTGTCAAAATGAGTTCTTACCTTTTGGCTTTTGTATTCGGTGA
ACTTCAATTTAAAAAAGGAAAAACAAAATCTGGTGTTGAAGTAGGTGCTTTTGCAACTAAAGATCATAGTGAAGCTGCGC
TTGATTTCCCGCTTGATATTGCTATTCGTTCAATTGAATTTTATGAAGATTACTATAAAACGCCATATCCACTCCCACAC
AGTTGGCACATTGCCTTACCTGACTTTTCGGCAGGAGCAATGGAAAACTGGGGATGTATCACTTATCGTGAAGTCTGCAT
GCTTGTTGACCCTGAAAATGCAACCATTCAAAGCAAACAATATGTAGCAACTGTTATTGCACACGAATTGGCACACCAAT
GGTTCGGTGACCTTGTAACAATGCAATGGTGGGATGATTTGTGGCTCAATGAATCATTTGCCAACAACATGGAATATGTT
TGTATGGATGCTTTGGAACCAAGTTGGAACGTTTGGGAATCATTCTCAATCTCAGAAGCCAATATGGCACTGAATCGTGA
TGCAACTGATGGAGTTCAATCTGTCCACGTTGAAGTGACTCATCCAGATGAAATTGGAACGCTCTTTGACCCAGCAATCG
TCTATGCCAAAGGTTCACGTTTGATGGTTATGCTTCGTAAATGGCTTGGAGATGAAGATTTTGCTGCTGGTTTAGCTCTT
TACTTCAAACGCCACCAATATGGAAATACAGTCGGAGATAATCTTTGGGATGCCTTGGCTGAAGTCTCTGGAAAAGATGT
GGCAGCTTTCATGCATTCATGGGTTAACCAACCAGGTTACCCTGTCGTTACTGCCGAAGTCATTGATGATACTTTAGTTT
TGAGTCAAAAACAATTCTTCGTTGGTGAGGGTGCTGATAAAGGACGTTTGTGGAATGTTCCTTTGAATACAAATTGGTCA
GGATTGCCAGACTTACTTTCTTCTGAAAAAGTTGAAATTCCTGGTTTTGCTGCTTTGAAAGCAAAAAATGATGGTAAGGC
CCTCTTTTTGAATGATGCAAATATGGCTCATTACATTATTGATTACAAAGGACAATTGTTGACAGACCTCCTCTCAGAAG
TTGAGACTTTGGAGAATGTCACTAAATTCCAAATCTTGCAAGATCGTAAATTATTGGCTAAAGCAGGTGTAATTTCTTAT
GCTGATGTCGTAAATATCTTGCCAGCATTTACCAACGAAGAATCTTACCTTGTCAATACTGGTTTGAGTCAACTCATTAG
CGAATTGGAACTTTTTGTTGATGAAGATTCAGAAACTGAAAAAGCTTTCCAAAGCTTGGTAGGAAAACTTTTCGCTAAAA
ACTATGCTCGCTTAGGTTGGGATAAAGTTGCTGGCGAATCTGCTGGTGATGAGAGCCTTCGTGGAATTGTTTTGAGTAAG
ACTTTGTATGCTGAGAATGCAGATGCCAAAGCAAAAGCCAGTCAAATCTTTGCAGCACATAAAGAAAATCTAGCAGGAAT
TCCGGCTGATATTCGTCCAATTGTTTTAAATAATGAAATTAAGACGACAAATTCTGCTGAATTGGTTAAAACTTATCGTG
AAACTTATGTTAAAACTAGCTTGCAAGAATTTAAACGTGAGCTTGAAGGGGCTGTCGCATTAATCAAGGATGAAAAAGTC
ATTGCTGAATTGCTTGAAAGCTTCAAAAATGCTGATATTGTTAAGCCACAAGATATTGCTTTCTCTTGGTTCTACCTTTT
GCGCAATGATTTCTCACAAGATGCTGCTTGGGCTTGGGAAAAAGCAAATTGGGCATTCCTTGAAGAAAAATTGGGTGGAG
ATATGAGTTATGATAAATTTGTTATCTATCCAGGAAATACTTTTAAAACTGCTGATAAATTAGCAGAATATAAAGCTTTC
TTTGAGCCAAAATTAGAAAATCAAGGTTTGAAACGTTCAATCGAAATGGCAATCAAGCAAATCACAGCACGTGTTGCTTT
GATTGATAGCCAAAAGGCTGACGTTGATAAATCAATCAAAGAAATTTCTGAAAAATTATAA

Upstream 100 bases:

>100_bases
TTTTTAGTAGTAAAAAGAATAGATGTAATTTTTCTTTGTACTCGAAATTTTCTATTCAATTTGATATAATTAGATTAATA
CTGAATATTTAGGAGAAAAC

Downstream 100 bases:

>100_bases
TAAATAAAAAATCACCTTTTTGAGGTGATTTTTTTTATTCATTCTTGGTCTGACTTTGTTTTTGATAGCACAAGTAGAGC
GATAATTAGAAAGATAAATC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alanine aminopeptidase; Lysyl aminopeptidase; Lys-AP

Number of amino acids: Translated: 846; Mature: 845

Protein sequence:

>846_residues
MAVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDSVIAFHAKGLHFSKVRAFSVDTNFIENEEDEEIVVKIGET
GRVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFESHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPE
LLNINGIHVFERTVKMSSYLLAFVFGELQFKKGKTKSGVEVGAFATKDHSEAALDFPLDIAIRSIEFYEDYYKTPYPLPH
SWHIALPDFSAGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVTMQWWDDLWLNESFANNMEYV
CMDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVTHPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLAL
YFKRHQYGNTVGDNLWDALAEVSGKDVAAFMHSWVNQPGYPVVTAEVIDDTLVLSQKQFFVGEGADKGRLWNVPLNTNWS
GLPDLLSSEKVEIPGFAALKAKNDGKALFLNDANMAHYIIDYKGQLLTDLLSEVETLENVTKFQILQDRKLLAKAGVISY
ADVVNILPAFTNEESYLVNTGLSQLISELELFVDEDSETEKAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSK
TLYAENADAKAKASQIFAAHKENLAGIPADIRPIVLNNEIKTTNSAELVKTYRETYVKTSLQEFKRELEGAVALIKDEKV
IAELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWAFLEEKLGGDMSYDKFVIYPGNTFKTADKLAEYKAF
FEPKLENQGLKRSIEMAIKQITARVALIDSQKADVDKSIKEISEKL

Sequences:

>Translated_846_residues
MAVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDSVIAFHAKGLHFSKVRAFSVDTNFIENEEDEEIVVKIGET
GRVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFESHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPE
LLNINGIHVFERTVKMSSYLLAFVFGELQFKKGKTKSGVEVGAFATKDHSEAALDFPLDIAIRSIEFYEDYYKTPYPLPH
SWHIALPDFSAGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVTMQWWDDLWLNESFANNMEYV
CMDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVTHPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLAL
YFKRHQYGNTVGDNLWDALAEVSGKDVAAFMHSWVNQPGYPVVTAEVIDDTLVLSQKQFFVGEGADKGRLWNVPLNTNWS
GLPDLLSSEKVEIPGFAALKAKNDGKALFLNDANMAHYIIDYKGQLLTDLLSEVETLENVTKFQILQDRKLLAKAGVISY
ADVVNILPAFTNEESYLVNTGLSQLISELELFVDEDSETEKAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSK
TLYAENADAKAKASQIFAAHKENLAGIPADIRPIVLNNEIKTTNSAELVKTYRETYVKTSLQEFKRELEGAVALIKDEKV
IAELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWAFLEEKLGGDMSYDKFVIYPGNTFKTADKLAEYKAF
FEPKLENQGLKRSIEMAIKQITARVALIDSQKADVDKSIKEISEKL
>Mature_845_residues
AVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDSVIAFHAKGLHFSKVRAFSVDTNFIENEEDEEIVVKIGETG
RVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFESHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPEL
LNINGIHVFERTVKMSSYLLAFVFGELQFKKGKTKSGVEVGAFATKDHSEAALDFPLDIAIRSIEFYEDYYKTPYPLPHS
WHIALPDFSAGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVTMQWWDDLWLNESFANNMEYVC
MDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVTHPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLALY
FKRHQYGNTVGDNLWDALAEVSGKDVAAFMHSWVNQPGYPVVTAEVIDDTLVLSQKQFFVGEGADKGRLWNVPLNTNWSG
LPDLLSSEKVEIPGFAALKAKNDGKALFLNDANMAHYIIDYKGQLLTDLLSEVETLENVTKFQILQDRKLLAKAGVISYA
DVVNILPAFTNEESYLVNTGLSQLISELELFVDEDSETEKAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSKT
LYAENADAKAKASQIFAAHKENLAGIPADIRPIVLNNEIKTTNSAELVKTYRETYVKTSLQEFKRELEGAVALIKDEKVI
AELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWAFLEEKLGGDMSYDKFVIYPGNTFKTADKLAEYKAFF
EPKLENQGLKRSIEMAIKQITARVALIDSQKADVDKSIKEISEKL

Specific function: Aminopeptidase with broad substrate specificity to several peptides. It has more affinity for oligopeptides than for dipeptides. It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm. Note=It may be secreted through an unknown mechanism (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family

Homologues:

Organism=Homo sapiens, GI158937236, Length=794, Percent_Identity=34.1309823677582, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI94818901, Length=892, Percent_Identity=30.6053811659193, Blast_Score=344, Evalue=2e-94,
Organism=Homo sapiens, GI94818891, Length=893, Percent_Identity=30.6830907054871, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI132814467, Length=745, Percent_Identity=28.8590604026846, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI194306629, Length=810, Percent_Identity=30, Blast_Score=304, Evalue=3e-82,
Organism=Homo sapiens, GI11641261, Length=810, Percent_Identity=30, Blast_Score=304, Evalue=3e-82,
Organism=Homo sapiens, GI157266300, Length=901, Percent_Identity=27.6359600443951, Blast_Score=290, Evalue=3e-78,
Organism=Homo sapiens, GI61742777, Length=871, Percent_Identity=27.2101033295063, Blast_Score=289, Evalue=8e-78,
Organism=Homo sapiens, GI61742775, Length=871, Percent_Identity=27.2101033295063, Blast_Score=288, Evalue=1e-77,
Organism=Homo sapiens, GI310123622, Length=365, Percent_Identity=41.3698630136986, Blast_Score=286, Evalue=7e-77,
Organism=Homo sapiens, GI310133497, Length=365, Percent_Identity=41.0958904109589, Blast_Score=278, Evalue=2e-74,
Organism=Homo sapiens, GI7019561, Length=850, Percent_Identity=28.5882352941176, Blast_Score=276, Evalue=7e-74,
Organism=Homo sapiens, GI194239713, Length=716, Percent_Identity=27.7932960893855, Blast_Score=217, Evalue=4e-56,
Organism=Homo sapiens, GI40316915, Length=364, Percent_Identity=24.4505494505494, Blast_Score=76, Evalue=2e-13,
Organism=Escherichia coli, GI1787163, Length=390, Percent_Identity=26.9230769230769, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71989076, Length=875, Percent_Identity=30.8571428571429, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71989071, Length=869, Percent_Identity=30.8400460299194, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI115533278, Length=909, Percent_Identity=29.1529152915292, Blast_Score=296, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI115533276, Length=909, Percent_Identity=29.1529152915292, Blast_Score=296, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI133903840, Length=783, Percent_Identity=27.4584929757344, Blast_Score=273, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17569221, Length=517, Percent_Identity=29.4003868471954, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17565628, Length=619, Percent_Identity=25.686591276252, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71990873, Length=361, Percent_Identity=31.8559556786704, Blast_Score=169, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17569225, Length=418, Percent_Identity=28.7081339712919, Blast_Score=166, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI193206928, Length=366, Percent_Identity=31.1475409836066, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193206926, Length=366, Percent_Identity=31.1475409836066, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71981298, Length=708, Percent_Identity=22.316384180791, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71993840, Length=348, Percent_Identity=24.7126436781609, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17544504, Length=324, Percent_Identity=26.5432098765432, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI9755335, Length=859, Percent_Identity=29.802095459837, Blast_Score=356, Evalue=9e-99,
Organism=Saccharomyces cerevisiae, GI6321837, Length=871, Percent_Identity=28.2433983926521, Blast_Score=318, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6322054, Length=748, Percent_Identity=25.5347593582888, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24655274, Length=866, Percent_Identity=30.8314087759815, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24655260, Length=866, Percent_Identity=30.8314087759815, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24655265, Length=866, Percent_Identity=30.8314087759815, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24655268, Length=866, Percent_Identity=30.8314087759815, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24655257, Length=866, Percent_Identity=30.8314087759815, Blast_Score=404, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24655252, Length=866, Percent_Identity=30.8314087759815, Blast_Score=404, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24646512, Length=874, Percent_Identity=27.5743707093822, Blast_Score=302, Evalue=6e-82,
Organism=Drosophila melanogaster, GI24646510, Length=874, Percent_Identity=27.5743707093822, Blast_Score=302, Evalue=6e-82,
Organism=Drosophila melanogaster, GI24646518, Length=883, Percent_Identity=27.519818799547, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24646516, Length=883, Percent_Identity=27.519818799547, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24646514, Length=879, Percent_Identity=27.7588168373151, Blast_Score=299, Evalue=5e-81,
Organism=Drosophila melanogaster, GI221379089, Length=851, Percent_Identity=28.7896592244418, Blast_Score=295, Evalue=8e-80,
Organism=Drosophila melanogaster, GI45550850, Length=775, Percent_Identity=28.1290322580645, Blast_Score=275, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24650973, Length=762, Percent_Identity=28.3464566929134, Blast_Score=275, Evalue=9e-74,
Organism=Drosophila melanogaster, GI24648790, Length=786, Percent_Identity=27.8625954198473, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI28571792, Length=716, Percent_Identity=27.9329608938547, Blast_Score=255, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24651025, Length=700, Percent_Identity=28, Blast_Score=252, Evalue=7e-67,
Organism=Drosophila melanogaster, GI24651023, Length=700, Percent_Identity=28, Blast_Score=252, Evalue=7e-67,
Organism=Drosophila melanogaster, GI24651021, Length=700, Percent_Identity=28, Blast_Score=252, Evalue=7e-67,
Organism=Drosophila melanogaster, GI21358341, Length=411, Percent_Identity=34.3065693430657, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI161078673, Length=796, Percent_Identity=26.8844221105528, Blast_Score=235, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28571901, Length=796, Percent_Identity=26.8844221105528, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24648786, Length=623, Percent_Identity=28.7319422150883, Blast_Score=233, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24651016, Length=327, Percent_Identity=35.1681957186544, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI221330574, Length=750, Percent_Identity=26.5333333333333, Blast_Score=207, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24641062, Length=640, Percent_Identity=25.625, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI221458256, Length=623, Percent_Identity=25.2006420545746, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281362224, Length=623, Percent_Identity=25.3611556982343, Blast_Score=163, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24648784, Length=419, Percent_Identity=29.1169451073986, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281362221, Length=325, Percent_Identity=30.7692307692308, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24641060, Length=712, Percent_Identity=23.0337078651685, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24584504, Length=488, Percent_Identity=25.2049180327869, Blast_Score=131, Evalue=3e-30,
Organism=Drosophila melanogaster, GI116008418, Length=262, Percent_Identity=24.8091603053435, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116008078, Length=262, Percent_Identity=24.8091603053435, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116007874, Length=694, Percent_Identity=19.4524495677233, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AMPN1_LACLA (Q9CIQ1)

Other databases:

- EMBL:   AE005176
- PIR:   A86663
- RefSeq:   NP_266461.1
- ProteinModelPortal:   Q9CIQ1
- GeneID:   1113915
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L102360
- NMPDR:   fig|272623.1.peg.313
- HOGENOM:   HBG515894
- OMA:   LIGTQFE
- ProtClustDB:   CLSK876725
- BioCyc:   LLAC272623:L102360-MONOMER
- BRENDA:   3.4.11.2
- GO:   GO:0005737
- GO:   GO:0006508
- InterPro:   IPR001930
- InterPro:   IPR014782
- PANTHER:   PTHR11533
- PRINTS:   PR00756

Pfam domain/function: PF01433 Peptidase_M1

EC number: =3.4.11.2

Molecular weight: Translated: 95337; Mature: 95206

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 289-289 ACT_SITE 375-375

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDSVIAFHAKGLHFSKVRAFSV
CCHHHHHHHHCCCCEEEEEEECCCCCEECCEEEEECCCCCCEEEEEECCCEEHHEEEEEE
DTNFIENEEDEEIVVKIGETGRVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFE
CCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCHHCCCCCEEEECCCEEEEEECCHH
SHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPELLNINGIHVFERTVKMSSYL
HHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHH
LAFVFGELQFKKGKTKSGVEVGAFATKDHSEAALDFPLDIAIRSIEFYEDYYKTPYPLPH
HHHHHHHHEECCCCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCC
SWHIALPDFSAGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVT
CEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
MQWWDDLWLNESFANNMEYVCMDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVT
HHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEEE
HPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLALYFKRHQYGNTVGDNLWDALA
CCHHCCCHHCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EVSGKDVAAFMHSWVNQPGYPVVTAEVIDDTLVLSQKQFFVGEGADKGRLWNVPLNTNWS
HCCCCHHHHHHHHHHCCCCCCEEEHHHHCCHHHCCCCCEEEECCCCCCEEEECCCCCCCC
GLPDLLSSEKVEIPGFAALKAKNDGKALFLNDANMAHYIIDYKGQLLTDLLSEVETLENV
CCHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHH
TKFQILQDRKLLAKAGVISYADVVNILPAFTNEESYLVNTGLSQLISELELFVDEDSETE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHH
KAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSKTLYAENADAKAKASQIFAAH
HHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHCEEEEEHEEECCCCCCHHHHHHHHHHH
KENLAGIPADIRPIVLNNEIKTTNSAELVKTYRETYVKTSLQEFKRELEGAVALIKDEKV
HCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHH
IAELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWAFLEEKLGGDMSYDKF
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCCCEE
VIYPGNTFKTADKLAEYKAFFEPKLENQGLKRSIEMAIKQITARVALIDSQKADVDKSIK
EEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
EISEKL
HHHHCC
>Mature Secondary Structure 
AVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDSVIAFHAKGLHFSKVRAFSV
CHHHHHHHHCCCCEEEEEEECCCCCEECCEEEEECCCCCCEEEEEECCCEEHHEEEEEE
DTNFIENEEDEEIVVKIGETGRVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFE
CCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCHHCCCCCEEEECCCEEEEEECCHH
SHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPELLNINGIHVFERTVKMSSYL
HHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHH
LAFVFGELQFKKGKTKSGVEVGAFATKDHSEAALDFPLDIAIRSIEFYEDYYKTPYPLPH
HHHHHHHHEECCCCCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCC
SWHIALPDFSAGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVT
CEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEE
MQWWDDLWLNESFANNMEYVCMDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVT
HHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEEE
HPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLALYFKRHQYGNTVGDNLWDALA
CCHHCCCHHCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EVSGKDVAAFMHSWVNQPGYPVVTAEVIDDTLVLSQKQFFVGEGADKGRLWNVPLNTNWS
HCCCCHHHHHHHHHHCCCCCCEEEHHHHCCHHHCCCCCEEEECCCCCCEEEECCCCCCCC
GLPDLLSSEKVEIPGFAALKAKNDGKALFLNDANMAHYIIDYKGQLLTDLLSEVETLENV
CCHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHH
TKFQILQDRKLLAKAGVISYADVVNILPAFTNEESYLVNTGLSQLISELELFVDEDSETE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHH
KAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSKTLYAENADAKAKASQIFAAH
HHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHCEEEEEHEEECCCCCCHHHHHHHHHHH
KENLAGIPADIRPIVLNNEIKTTNSAELVKTYRETYVKTSLQEFKRELEGAVALIKDEKV
HCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHH
IAELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWAFLEEKLGGDMSYDKF
HHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCCCEE
VIYPGNTFKTADKLAEYKAFFEPKLENQGLKRSIEMAIKQITARVALIDSQKADVDKSIK
EEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
EISEKL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471